化合物简介
Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade. It induces sedation, hypothermia, ptosis, and (in higher doses) catalepsy; it inhibits spontaneous motor activity, conditioned avoidance response, amphetamine toxicity and stereotypy. Nuciferine may also potentiate morphine analgesia. The median lethal dose in mice is 289mg/kg. It is structurally related to apomorphine.
基本信息
中文名称
荷叶提取物
英文名称
NUCIFERINE
中文别名
荷叶碱NUCIFERIN、荷叶碱
英文别名
Sanjoinine E、l-nuciferine、nuciferin、l-5,6-dimethoxyaporphine、Nuciferin、R-(-)-nuciferine
CAS号
475-83-2
分子式
C19H21NO2
分子量
295.376
精确质量
295.157
PSA
21.7
LOGP
3.3938
编号系统
UNII
W26UEB90B7
物化性质
密度
1.15g/cm3
沸点
430.7ºC at 760mmHg
闪点
151.9ºC
折射率
1.596
蒸汽压
1.27E-07mmHg at 25°C