4-氨基安替比林

4-氨基安替比林

CAS号：83-07-8

英文名：4-aminoantipyrine

分子式

C11H13N3O

熔点

105-110°C(lit.)

密度

0.8

分子量

203.24

沸点

340ºC

溶解度

ca. 500 g/L (20 ºC)

信号词

Warning

危险品标志

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化合物简介

Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. Due to the risk of agranulocytosis its use as a drug is discouraged. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates liver microsomes and is also used to measure extracellular water.

基本信息

中文名称

4-氨基安替比林

英文名称

4-aminoantipyrine

中文别名

4-氨基非那宗、4-氨基-2,3-二甲基-1-苯基-5-吡唑啉酮、1,5-二甲基-2-苯基-4-氨基-3-吡唑啉酮、4-氨基安替吡啉

英文别名

4-amino-1,5-dimethyl-2-phenylpyrazol-3-one、4-Aminoantipyrine、3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-

CAS号

83-07-8

分子式

C11H13N3O

分子量

203.24

精确质量

203.106

PSA

52.95

LOGP

1.6478

编号系统

EINECS号

201-452-3

MDL号

MFCD00003145

物化性质

外观与性状

黄色结晶粉末

密度

0.8

沸点

340ºC

熔点

105-110°C(lit.)

折射率

1.606

水溶解性

ca. 500 g/L (20 ºC)

稳定性

Stable. May be light sensitive.

储存条件

Store at RT.

安全信息

RTECS号

CD2480000

安全说明

S26-S36-S36/37/39

危险类别码

R22; R36/37/38

WGK Germany

3

海关编码

29331190

危险品标志

Xn

危险性防范说明

P301 + P312 + P330

危险标志

GHS07

信号词

Warning

危险性描述

H302

合成路线

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氨基比林

4-氨基安替比林

4-氨基安替比林

4-(甲氨基)安替比林

4-(甲氨基)安替比林

4-(N,N-dimethyl)-4'-hydroxyaminoantipyrine

4-(N,N-dimethyl)-4'-hydroxyaminoantipyrine

4-(N,N-dimethyl)-3'-hydroxyaminoantipyrine

4-(N,N-dimethyl)-3'-hydroxyaminoantipyrine

4-(N,N-dimethyl)-2'-hydroxyaminoantipyrine

4-(N,N-dimethyl)-2'-hydroxyaminoantipyrine

上游原料

共找到17个上游原料 >

安替比林

安乃近

(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-sulfamic acid

(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-sulfamic acid

下游产品

共找到55个下游商品 >

N-[1-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-1-oxobutan-2-yl]benzamide

N-[1-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-1-oxobutan-2-yl]benzamide

N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)thiophene-2-carboxamide

N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)thiophene-2-carboxamide

4-异硫氰酸-1,5-二甲基-2-苯基-1,2-二氢吡唑-3-酮

4-异硫氰酸-1,5-二甲基-2-苯基-1,2-二氢吡唑-3-酮

异丙氨基比林

异丙氨基比林

1,5-dimethyl-4-[[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-phenylpyrazol-3-one

1,5-dimethyl-4-[[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-phenylpyrazol-3-one

5-methyl-2-phenylpyrazole-3,4-dione

5-methyl-2-phenylpyrazole-3,4-dione

上游原料

乙醇硫酸安替比林安乃近 (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-sulfamic acid 水 1,5,5'-trimethyl-2,2'-diphenyl-1,2,2',4'-tetrahydro-4,4'-azanylylidene-bis-pyrazol-3-one 4-N-(3,4-methylenedioxybenzalidine)-aminoantipyrine 盐酸 5-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)-barbituric acid 4-[(2,2,2-Trichlor-1,1-dimethylethoxycarbonyl)amino]antipyrin N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)benzamide [(1,5-二甲基-3-氧代-2-苯基吡唑-4-基)氨基]甲烷磺酸钠氨基比林 2,3-二甲基-4-亚硝基-1-苯基-3-吡唑啉-5-酮 1,5-dimethyl-4-nitro-2-phenyl-1,2-dihydro-pyrazol-3-one 醋酸

下游产品

N-[1-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-1-oxobutan-2-yl]benzamide N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)thiophene-2-carboxamide 4-异硫氰酸-1,5-二甲基-2-苯基-1,2-二氢吡唑-3-酮异丙氨基比林 1,5-dimethyl-4-[[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-phenylpyrazol-3-one 5-methyl-2-phenylpyrazole-3,4-dione 1-(1,5-二甲基-3-氧代-2-苯基吡唑-4-基)-3-吡啶-2-基硫脲 5-hydroxy-1,5-dimethyl-3-phenyl-imidazolidine-2,4-dione Methyltartronic acid anilide methylamide N-methyl-N'-phenylacetohydrazide 2-氰基-N-(1,5-二甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-基)-乙酰胺安乃近一水合物 4-甲酰氨基安替吡啉 4,5-二氢-4-甲基-6-氧代-5-苯基-6H-吡唑并[4,5-c]异硒唑 4-乙酰氨基安替比林 2-甲基氨基-2-(苯基氨基甲酰)丙酸 N-安替比林基-1,3-二氧代-alpha-乙基-2-异吲哚啉乙酰胺水杨酰胺基非那宗 2-苯基-2-丙醇 N-(1-(安替比林基氨基甲酰)戊基)-苯甲酰胺乙醛酸 1-(1,5-二甲基-3-氧代-2-苯基吡唑-4-基)-3-(4-乙氧基苯基)硫脲 1,3-bis(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)urea 1-(1,5-二甲基-3-氧代-2-苯基吡唑-4-基)-3-(4-甲氧基苯基)硫脲 4-[(3-methoxyphenyl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one butyltin(3+),2-(5-methoxy-5-oxopentanoyl)oxyethanethiolate N-(1,5-二甲基-3-氧代-2-苯基-吡唑-4-基)-3-碘-4-甲基-苯甲酰胺 1-环己基-3-(1,5-二甲基-3-氧代-2-苯基吡唑-4-基)硫脲尼芬那宗 1,3-双-(1,5-二甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-基)-硫脲 methyl N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-N-methylcarbamate 1-(3-氯苯基)-3-(1,5-二甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-基)脲 4-羟基安替比林 1,5-dimethyl-4-[(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)diazenyl]-2-phenylpyrazol-3-one N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)benzamide 2-氯-n-(1,5-二甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-基)乙酰胺 [(1,5-二甲基-3-氧代-2-苯基吡唑-4-基)氨基]甲烷磺酸钠 2-氯-N-(1,5-二甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-基)丙酰胺 4-amino-2,4-dihydro-5-methyl-2-phenyl-3H-Pyrazol-3-one 4-[(4-methoxyphenyl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one 4-(甲氨基)安替比林 ethyl N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)carbamate 氨丙吡酮 2-[4-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)carbamoyl]-2-oxo-3,3-diphenylindol-1-yl]acetic acid 2,3-二甲基-5-氧代-1-苯基-3-吡唑啉-4-氨基甲酸甲酯