Omecamtiv mecarbil_CAS号:873697-71-3_分子式、生产方法、用途、产品-灵元素

化合物简介

CK 1827452 is a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction.

基本信息

中文名称

Omecamtiv mecarbil

英文名称

methyl 4-[[2-fluoro-3-[(6-methylpyridin-3-yl)carbamoylamino]phenyl]methyl]piperazine-1-carboxylate

中文别名

英文别名

methyl 4-(2-fluoro-5-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate、methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate、methyl 4-[(2-fluoro-3-{[(6-methyl(3-pyridyl))amino]carbonylamino}phenyl)methyl]piperazinecarboxylate、Omecamtiv mecarbil (USAN/INN)、Omecamtiv mecarbil

CAS号

873697-71-3

分子式

C20H24FN5O3

分子量

401.435

精确质量

401.186

PSA

90.29

LOGP

3.0195