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马沙骨化醇

马沙骨化醇

CAS号：103909-75-7

英文名：Maxacalcitol

分子式

C26H42O4

熔点

密度

1.09 g/cm3

分子量

418.609

沸点

581.4ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

22-Oxacalcitriol is the noncalcemic analogue of vitamine D and was found to suppress parathyroid hormone synthesis and secretion.

基本信息

中文名称

马沙骨化醇

英文名称

Maxacalcitol

中文别名

玛莎骨化醇

英文别名

22-Oxacalcitriol、1R,25-dihydroxy-22-oxavitamin D3、1alpha,25-Dihydroxy-22-oxavitamin D3、MC 1275、22-Oxa-1,25-dihydroxyvitamin D3、1,25-Dihydroxy-22-oxavitamin D3、Prezios、(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

CAS号

103909-75-7

分子式

C26H42O4

分子量

418.609

精确质量

418.308

PSA

69.92

LOGP

4.6935

编号系统

UNII

N2UJM5NBF6

物化性质

密度

1.09 g/cm3

沸点

581.4ºC at 760mmHg

闪点

305.4ºC

折射率

1.549

蒸汽压

6.11E-16mmHg at 25°C

合成路线

(6Z)-(1S,3R,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5(10),6,8-triene-1,3-diol

(6Z)-(1S,3R,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5(10),6,8-triene-1,3-diol

马沙骨化醇

马沙骨化醇

上游原料

共找到20个上游原料 >

(17Z)-(1S,3R)-1,3-bis(tert-butyldimethylsilyloxy)pregna-5, 17-dien

(17Z)-(1S,3R)-1,3-bis(tert-butyldimethylsilyloxy)pregna-5, 17-dien

ethyl 3-((S)-1-((1S,3aS,7aS,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)ethoxy)propanoate

ethyl 3-((S)-1-((1S,3aS,7aS,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)ethoxy)propanoate

(1S,3R,20S)-1,3-bis(tert-butyldimethylsilyloxy)-20-(3-hydroxy-3-methylbuthyloxy)pregn-5-ene

(1S,3R,20S)-1,3-bis(tert-butyldimethylsilyloxy)-20-(3-hydroxy-3-methylbuthyloxy)pregn-5-ene

ethyl 3-((S)-1-((1S,3aR,7aR)-7a-methyl-4-oxooctahydro-1H-inden-1-yl)ethoxy)propanoate

ethyl 3-((S)-1-((1S,3aR,7aR)-7a-methyl-4-oxooctahydro-1H-inden-1-yl)ethoxy)propanoate

(1S,3R,20S)-1,3-bis(tert-butyldimethylsilyloxy)-20-(2,3-epoxy-3-methylbutyloxy)pregn-5-ene

(1S,3R,20S)-1,3-bis(tert-butyldimethylsilyloxy)-20-(2,3-epoxy-3-methylbutyloxy)pregn-5-ene

1-溴-3-甲基-2-丁烯

1-溴-3-甲基-2-丁烯

上游原料

(17Z)-(1S,3R)-1,3-bis(tert-butyldimethylsilyloxy)pregna-5, 17-dien ethyl 3-((S)-1-((1S,3aS,7aS,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)ethoxy)propanoate (1S,3R,20S)-1,3-bis(tert-butyldimethylsilyloxy)-20-(3-hydroxy-3-methylbuthyloxy)pregn-5-ene ethyl 3-((S)-1-((1S,3aR,7aR)-7a-methyl-4-oxooctahydro-1H-inden-1-yl)ethoxy)propanoate (1S,3R,20S)-1,3-bis(tert-butyldimethylsilyloxy)-20-(2,3-epoxy-3-methylbutyloxy)pregn-5-ene 1-溴-3-甲基-2-丁烯 2-甲基-3-丁烯-2-醇 1α,3β-Bis[(tert-butyldimethylsilyl)oxy]androst-5-en-17-one ethyl 3-((S)-1-((1S,3aR,4S,7aS)-4-hydroxy-7a-methyloctahydro-1H-inden-1-yl)ethoxy)propanoate 4-{(S)-1-[(1S,3R,9S,10R,13S,14R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-ethoxy}-2-methyl-butan-2-ol 3-(bromomethyl)-2,2-dimethyloxirane [3S-(1Z,3a,5b)]-[2-[3,5-二[(叔丁基)二甲基硅氧基]-2-亚甲基环己亚基]乙基]二苯基氧化膦 2-Butanone, 4-[[(1α,3β,20S)-1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]pregn-5-en-20-yl]oxy]- 甲基锂 1-羟基去氢表雄酮 1α,3β-bis(tertbutyldimethylsilyloxy)-20α-(3-oxobutyloxy)-5,7-pregnadiene 20-(3-羟基-3-甲基丁氧基)孕甾-5,7-二烯-1,3-二醇 1α,3β-bis(tert-butyldimethylsilyloxy)-20(S)-(2-ethyloxycarbonylethyloxy)pregna-5,7-diene ethyl 3-((S)-1-((1S,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)ethoxy)propanoate (6Z)-(1S,3R,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5(10),6,8-triene-1,3-diol