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p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

CAS号：105420-68-6

英文名：p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

分子式

C27H26N4O10S

熔点

密度

分子量

598.581

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

英文名称

p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

中文别名

英文别名

p-nitrobenzyl (5R,6S)-6-((1R)-hydroxyethyl)-2-((2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl)-2-penem-3-carboxylate、(5R,6S)-6-((R)-1-Hydroxy-ethyl)-3-[(S)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

CAS号

105420-68-6

分子式

C27H26N4O10S

分子量

598.581

精确质量

598.137

PSA

213.32

LOGP

4.3933

合成路线

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

p-nitrobenzyl (5R,6S)-6-<(1R)-hydroxyethyl>-2-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>-2-penem-3-carboxylate

上游原料

共找到6个上游原料 >

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthioazetidin-2-one

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthioazetidin-2-one

(R)-Pyrrolidine-1,2-dicarboxylic acid 1-(4-nitro-benzyl) ester

(R)-Pyrrolidine-1,2-dicarboxylic acid 1-(4-nitro-benzyl) ester

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthio>-2-oxoazetidin-1-yl>-2-triphenylphosphoranylideneacetate

p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthio>-2-oxoazetidin-1-yl>-2-triphenylphosphoranylideneacetate

(S)-2-{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1-[chloro-(4-nitro-benzyloxycarbonyl)-methyl]-4-oxo-azetidin-2-ylsulfanylcarbonyl}-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

(S)-2-{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1-[chloro-(4-nitro-benzyloxycarbonyl)-methyl]-4-oxo-azetidin-2-ylsulfanylcarbonyl}-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthio>-2-oxoazetidin-1-yl>-2-hydroxyacetate

p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthio>-2-oxoazetidin-1-yl>-2-hydroxyacetate

上游原料

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthioazetidin-2-one (R)-Pyrrolidine-1,2-dicarboxylic acid 1-(4-nitro-benzyl) ester (2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthio>-2-oxoazetidin-1-yl>-2-triphenylphosphoranylideneacetate (S)-2-{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1-[chloro-(4-nitro-benzyloxycarbonyl)-methyl]-4-oxo-azetidin-2-ylsulfanylcarbonyl}-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<<(2S)-N-p-nitrobenzyloxycarbonylpyrrolidin-2-yl>carbonylthio>-2-oxoazetidin-1-yl>-2-hydroxyacetate