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20R-喜树碱

20R-喜树碱

CAS号:110351-92-3
英文名:(R)-(-)-Camptothecin
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化合物简介
Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent.
基本信息
物化性质
上游原料
4-iodo-2-methoxy-6-trimethylsilanyl-3-pyridinecarboxaldehyde 2-(methoxycarbonyl)-2-(methoxymethoxy)butanoic acid 4-ethyl-1,12-dihydro-14H-pyrano[3',4':6,7indolizino[1,2-b]]quinolin-14-one 3-Methoxymethyl-quinoline-2-carboxylic acid methyl ester 乙基丙二酸二甲酯 (S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone 4'-ethyl-1',4',7',8'-tetrahydro-4'-hydroxy-3'H,10'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione (S)-4-ethyl-4-hydroxy-6-iodo-8-methoxy-1,4-dihydro-pyrano[3,4-c]pyridin-3-one 2-甲氧基-6-(三甲基硅烷基)吡啶 4-ethyl-8-methoxy-6-(trimethylsilyl)-1H-pyrano[3,4-c]pyridine methyl 4-ethyl-8-methoxy-1H-pyrano[3,4-c]pyridine-6-carboxylate (S)-(+)-4-ethyl-4-hydroxy-8-methoxy-6-(trimethylsilyl)-1,4-dihydro-3H-pyrano[3,4-c]pyridin-3-one methyl 4-ethyl-8-oxo-7,8-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylate 4-ethyl-6-chloro-8-methoxy-1H-pyrano[3,4-c]pyridine 2-methoxy-6-(trimethylsilyl)nicotinaldehyde 2-氯-3-甲基喹啉 dimethyl 2-ethyl-2-hydroxymalonate methyl 3-methylquinoline-2-carboxylate (S)-4-Ethyl-4-hydroxy-6-iodo-3-oxo-7-propargyl-1H-pyrano[3,4-c]-8-pyridone dimethyl [2-[3-(methoxymethyl)quinolin-2-yl]-2-oxoethyl]phosphonate phenyl isocyanate 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine 4-ethyl-8-oxo-N-phenyl-7-(prop-2-ynyl)-7,8-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxamide methyl 4-ethyl-8-oxo-7-(prop-2-ynyl)-7,8-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylate (R)-N,N-diethyl-2-formyl-2-(methoxymethoxy)butanamide 4-ethyl-8-oxo-7-(prop-2-ynyl)-7,8-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid 2-Carbomethoxy-3-brommethylchinolin 2-氨基苯甲醛 methyl 2-(diethylcarbamoyl)-2-(methoxymethoxy)butanoate 2-(diethylcarbamoyl)-2-(methoxymethoxy)butanoic acid