化合物简介
Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT). It was patented as an antiparkinsonian agent but was never marketed.
基本信息
中文名称
硝替卡朋
英文名称
3-[(3,4-dihydroxy-5-nitrophenyl)methylidene]pentane-2,4-dione
中文别名
英文别名
3-(3,4-dihydroxy-5-nitrobenzylidene)-2,4-pentanedione、2,4-Pentanedione,3-((3,4-dihydroxy-5-nitrophenyl)methylene)、Nitecapone、3-(3,4-dihydroxy-5-nitrophenyl)methylene-2,4-pentanedione、Nitecapona [INN-Spanish]、Nitecapone [INN]、OR 462、Nitecaponum [INN-Latin]
CAS号
116313-94-1
分子式
C12H11NO6
分子量
265.219
精确质量
265.059
PSA
120.42
LOGP
2.0906
物化性质
密度
1.451g/cm3
沸点
495.3ºC at 760 mmHg
闪点
211.6ºC
折射率
1.645
蒸汽压
1.95E-10mmHg at 25°C
安全信息
危险性描述
H301
危险标志
GHS06
信号词
Danger
危险性防范说明
P301 + P310
