基本信息
中文名称
PSI 7976
英文名称
sofosbuvir
中文别名
英文别名
(S)-2-{(R)-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylamino}propionic acid isopropyl ester、PSI-7976、(S)((((2R,3R,4R,5R)-5-(2,4-dicarbonyl-3,4-dihydropyrimidine-1(2Η)-yl)-4-fluoro-3-hydroxy-4-tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanine isopropyl ester、(2S)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4- methyltetrahydrofuran-2-yl)methoxy)phenoxyphosphoryl)amino)propanoate、Sofosbuvir (R)-Phosphate、(2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate、(S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propionoate、(S)-2-{(R)-[(1R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(R)-fluoro-3-hydroxy-4-methyI-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino}propionic acid (S)-isopropyl ester
CAS号
1190308-01-0
分子式
C22H29FN3O9P
分子量
529.453
精确质量
529.163
PSA
167.99
LOGP
2.0474
合成路线
