百科

乙莫克舍

CAS号：124083-20-1

英文名：R-(+)-Etomoxir

分子式

C17H23ClO4

熔点

密度

1.163g/cm3

分子量

326.815

沸点

405ºC at 760mmHg

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

An inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oexidation of long-chain acyl CoA esters. A strong inhibitor of mitochondrial CPT1 and is a candidate as an anti-diabetic drug.

基本信息

中文名称

乙莫克舍

英文名称

R-(+)-Etomoxir

中文别名

英文别名

R-(+)-ETOMOXIR

CAS号

124083-20-1

分子式

C17H23ClO4

分子量

326.815

精确质量

326.128

PSA

48.06

LOGP

4.0014

编号系统

UNII

MSB3DD2XP6

物化性质

密度

1.163g/cm3

沸点

405ºC at 760mmHg

闪点

142.6ºC

折射率

1.52

蒸汽压

0mmHg at 25°C

合成路线

106-48-9

对氯苯酚

191412-56-3

ethyl (2R)-2-(6-hydroxyhexyl)oxirane-2-carboxylate

上游原料

2-(6-benzyloxy)hexyl-2-en-propionic acid

37136-99-5

1-(6-bromohexoxy)-4-chlorobenzene

54247-27-7

苄基6-溴己醚

191412-56-3

ethyl (2R)-2-(6-hydroxyhexyl)oxirane-2-carboxylate

191412-51-8

(8-(benzyloxy)-2-methyleneoctanoyl)-L-proline

191412-48-3

ethyl 8-(benzyloxy)-2-methyleneoctanoate

上游原料

2-(6-benzyloxy)hexyl-2-en-propionic acid 1-(6-bromohexoxy)-4-chlorobenzene 苄基6-溴己醚 ethyl (2R)-2-(6-hydroxyhexyl)oxirane-2-carboxylate (8-(benzyloxy)-2-methyleneoctanoyl)-L-proline ethyl 8-(benzyloxy)-2-methyleneoctanoate (3S,8aS)-3-(6-Benzyloxy-hexyl)-3-bromomethyl-tetrahydro-pyrrolo[2,1-c][1,4]oxazine-1,4-dione 乙基8-(4-氯苯氧基)-2-亚甲基-辛酸酯 6-溴正己醇 ethyl (8-(benzyloxy)-2-methyleneoctanoyl)-L-prolinate (S)-2-Bromomethyl-2,8-dihydroxy-octanoic acid 8-(4-Chloro-phenoxy)-2-methylene-octanoyl chloride ethyl 2,3-dihydroxy-2-[6-(p-chlorophenoxy)hexyl]propanoate 8-(4-氯苯氧基)-1-辛烯-2-醇 (R)-8-(4-Chloro-phenoxy)-2-hydroxy-2-methanesulfonyloxymethyl-octanoic acid ethyl ester (S)-(2-(6-(4-chlorophenoxy)hexyl)oxiran-2-yl)methanol 8-(4-氯苯氧基)-2-亚甲基辛酸 ethyl (R)-2,3-dihydroxy-2-[6-(p-chlorophenoxy)hexyl]propanoate 硫酸二乙酯对氯苯酚