百科

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

CAS号：124930-59-2

英文名：[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

分子式：C10H13N5O6P+

分子量：330.214

合成路线

3'-azido-3'-deoxythymidin-5'-yl 4-methoxyphenyl α-hydroxy(phenyl)methylphosphonate

3'-azido-3'-deoxythymidin-5'-yl 4-methoxyphenyl α-hydroxy(phenyl)methylphosphonate

4-甲氧基苯酚

4-甲氧基苯酚

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

3'-azido-3'-deoxythymidin-5'-yl 4-chlorophenyl α-hydroxy(phenyl)methylphosphonate

3'-azido-3'-deoxythymidin-5'-yl 4-chlorophenyl α-hydroxy(phenyl)methylphosphonate

对氯苯酚

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

O-benzyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate

O-benzyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl) H-phosphonate diester

5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl) H-phosphonate diester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

1-Hydroxy-1-phenylmethylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

1-Hydroxy-1-phenylmethylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

1-Hydroxy-1-(4-methylphenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

1-Hydroxy-1-(4-methylphenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

1-Hydroxy-1-(4-chlorophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

1-Hydroxy-1-(4-chlorophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

1-Hydroxy-1-(4-methoxyphenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

1-Hydroxy-1-(4-methoxyphenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

1-Hydroxy-1-(4-cyanophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

1-Hydroxy-1-(4-cyanophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl)-O'-(4-cyanobenzyl) phosphotriester

5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl)-O'-(4-cyanobenzyl) phosphotriester

1-Hydroxy-1-(3-nitrophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

1-Hydroxy-1-(3-nitrophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

齐多夫定

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium

5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl)-O'-(3-nitrobenzyl) phosphotriester

5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl)-O'-(3-nitrobenzyl) phosphotriester

上游原料

1-Hydroxy-1-(4-chlorophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester 3'-azido-3'-deoxythymidin-5'-yl 4-methoxyphenyl α-hydroxy(phenyl)methylphosphonate O-benzyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate 3'-azido-3'-deoxythymidin-5'-yl 4-chlorophenyl α-hydroxy(phenyl)methylphosphonate 1-Hydroxy-1-(4-methylphenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester 5',5'-Di-O-(3'-azido-2',3'-dideoxythymidinyl) H-phosphonate diester 1-Hydroxy-1-phenylmethylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester 1-Hydroxy-1-(4-cyanophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester 1-Hydroxy-1-(4-methoxyphenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester 1-Hydroxy-1-(3-nitrophenyl)methylphosphonate 5',5'-di-O-(3'-azido-2',3'-dideoxythymidinyl) ester

下游产品

齐多夫定 3'-叠氮基-3'-脱氧-5'-胸苷酸