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5-乙酰氨基-7,8,9-O-三乙酰基-2,6-脱水-4-叠氮-3,4,5-三脱氧-D-甘油-D-半乳-2-壬烯酸甲酯

CAS号：130525-58-5

英文名：Zanamivir Azide Triacetate Methyl Ester

分子式

C18H24N4O10

熔点

密度

分子量

456.404

沸点

溶解度

信号词

危险品标志

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化合物简介

An intermediate used in the preparation of Zanamivir derivatives.

基本信息

中文名称

5-乙酰氨基-7,8,9-O-三乙酰基-2,6-脱水-4-叠氮-3,4,5-三脱氧-D-甘油-D-半乳-2-壬烯酸甲酯

英文名称

Zanamivir Azide Triacetate Methyl Ester

中文别名

(4S,5R,6R)-5-乙酰氨基-4-叠氮基-6-(1S,2R,3-三乙酰氧基丙基)-5,6-二氢-4H-吡喃-2-甲酸

英文别名

D-GLYCERO-D-GALACTO-NON-2-ENONIC ACID

CAS号

130525-58-5

分子式

C18H24N4O10

分子量

456.404

精确质量

456.149

PSA

193.28

LOGP

-0.10414

编号系统

EINECS号

603-423-4

物化性质

外观与性状

灰白色固体

合成路线

共找到5条合成路线 >

78850-37-0

甲基(3aR,4R,7aR)-2-甲基-4-[(1S,2R)-1,2,3-三乙酰氧基丙基]-3a,7a-二氢-4H-吡喃并[3,4-d][1,3]恶唑-6-羧酸酯

130525-58-5

5-乙酰氨基-7,8,9-O-三乙酰基-2,6-脱水-4-叠氮-3,4,5-三脱氧-D-甘油-D-半乳-2-壬烯酸甲酯

上游原料

共找到39个上游原料 >

691356-36-2

(1S,2R)-2-acetamido-1-((4R,4'R,5S)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)pent-4-en-1-yl methanesulfonate

19342-33-7

(2S,4S,5S,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydro xypropyl]tetrahydropyran-2-carboxylic acid

1372800-46-8

(1S,2R)-1-((2R,3R)-3-acetamido-6-(benzoyloxy)-6-(methoxycarbonyl)-3,6-dihydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate

78850-37-0

甲基(3aR,4R,7aR)-2-甲基-4-[(1S,2R)-1,2,3-三乙酰氧基丙基]-3a,7a-二氢-4H-吡喃并[3,4-d][1,3]恶唑-6-羧酸酯

639476-05-4

(4R,5S,6R,7R,8R)-N4-benzyl-N4-acetyl-5-benzyloxy-6,7:8,9-di-O-isopropylidene-1-nonene

163860-78-4

methyl (methyl 5-acetamido-7,8,9-tri-O-acetyl-4-azido-3,4,5-trideoxy-2-thio-D-glycero-α-D-galacto-nonulopyranosid)onate

下游产品

上游原料

(1S,2R)-2-acetamido-1-((4R,4'R,5S)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)pent-4-en-1-yl methanesulfonate (2S,4S,5S,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydro xypropyl]tetrahydropyran-2-carboxylic acid (1S,2R)-1-((2R,3R)-3-acetamido-6-(benzoyloxy)-6-(methoxycarbonyl)-3,6-dihydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate 甲基(3aR,4R,7aR)-2-甲基-4-[(1S,2R)-1,2,3-三乙酰氧基丙基]-3a,7a-二氢-4H-吡喃并[3,4-d][1,3]恶唑-6-羧酸酯 (4R,5S,6R,7R,8R)-N4-benzyl-N4-acetyl-5-benzyloxy-6,7:8,9-di-O-isopropylidene-1-nonene methyl (methyl 5-acetamido-7,8,9-tri-O-acetyl-4-azido-3,4,5-trideoxy-2-thio-D-glycero-α-D-galacto-nonulopyranosid)onate (5R,6R,7R,8R,E)-methyl 5-acetamido-7,8,9-tris(benzyloxy)-2,6-bis((tert-butyldimethylsilyl)oxy)non-2-enoate (4R,5S,6R,7R,8R)-N4-benzyl-5-benzyloxy-6,7:8,9-di-O-isopropylidene-1-nonene N-((4R,5R,6R,7R)-6,7,8-tris(benzyloxy)-5-((tert-butyldimethylsilyl)oxy)oct-1-en-4-yl)acetamide methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-β-D-galacto-non-2-ulopyranosyl chloride N-((3R,4R,5R,6R)-5,6,7-tris(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-1-oxoheptan-3-yl)acetamide N-((4R,5R,6S,7R)-6,7,8-tris(benzyloxy)-5-hydroxyoct-1-en-4-yl)acetamide (1S,2R)-1-((2R,3R,4S,6R)-3-acetamido-6-acetoxy-4-azido-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate (4R,5R)-tert-butyl 4-allyl-2,2-dimethyl-5-((1S,2R)-1,2,3-tris(benzyloxy)propyl)oxazolidine-3-carboxylate methyl (5-acetamido-7,8,9-tri-O-acetyl-4-azido-2-chloro-3,4,5-trideoxy-β-D-glycerol-D-galacto-2-nonulopyranosid)onate (4R,5R)-tert-butyl 4-allyl-5-((2S,3S)-3-(hydroxymethyl)oxiran-2-yl)-2,2-dimethyloxazolidine-3-carboxylate 双丙酮半乳糖 (4R,5R)-tert-butyl 4-allyl-2,2-dimethyl-5-((1R,2R)-1,2,3-trihydroxypropyl)oxazolidine-3-carboxylate methyl (2S,4S,5R,6R)-5-acetamido-4-azido-2-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylate (4R,5S)-tert-butyl 4-allyl-5-((E)-3-((4-methoxybenzyl)oxy)prop-1-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate (1R,2S)-2-azido-1-((4S,4'R,5R)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)pent-4-en-1-amine (4R,5S)-tert-butyl 4-allyl-5-((E)-3-hydroxyprop-1-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate methyl (4S,5R)-5-acetamido-4-azido-2-oxo-5-((4S,4'R,5R)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)pentanoate 1-((2R,3R)-2-allyl-3-((4S,4'R,5R)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)aziridin-1-yl)ethan-1-one methyl (4S,5R)-5-acetamido-4-azido-2-hydroxy-5-((4S,4'R,5R)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)pentanoate methyl 5-acetamido-2,7,8,9-tetra-O-acetyl-3,4,5-trideoxy-D-manno-2-nonulopyranosonate tert-butyl ((4R,5S,E)-5-hydroxy-8-((4-methoxybenzyl)oxy)octa-1,6-dien-4-yl)carbamate N-{(R)-1-[(S)-Hydroxy-((4R,5R,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-methyl]-but-3-enyl}-acetamide N-((1R,2S)-2-azido-4,5-dihydroxy-1-((4S,4'R,5R)-2,2,2',2'-tetramethyl-[4,4'-bi(1,3-dioxolan)]-5-yl)pentyl)acetamide (4S,5R,E)-1-((4-methoxybenzyl)oxy)-5-nitroocta-2,7-dien-4-ol Methyl 5-acetamido-7,8,9-tri-O-acetyl-2,6-anhydro-3,5-dideoxy-D-glycero-D-talo-non-2-enonate N-[(1R,2S)-2-Azido-1-((4S,5R,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-pent-4-enyl]-acetamide (2R,3R,4S)-3-乙酰氨基-4-乙酰氧基-2-((1R,2R)-1,2,3-三乙酰氧基丙基)-3,4-二氢-2H-吡喃-6-羧酸甲酯 methyl (5-acetamido-7,8,9-tri-O-acetyl-2,6-anhydro-2,3,4,5-tetradeoxy-D-glycero-D-galacto-non-2-enpyranosyl)onate Neu5Ac methyl ester

下游产品

N-氰基扎那米韦胺三乙酸酯甲酯扎那米韦中间体2 扎那米韦扎那米韦扎那米韦叠氮化物甲酯