化合物简介
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine Methyl Ester is an intermediate in the synthesis of MDV 3100, is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.
基本信息
中文名称
N-[3-氟-4-[(甲基氨基)羰基]苯基]-2-甲基-丙氨酸甲酯
英文名称
methyl 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methyl-propanoat e
中文别名
英文别名
1,1-Dimethyl-4-(2-carbomethoxyphenyl)-3-thiosemicarbazide、methyl 2(3\'-dimethylaminothioureido)benzoate、Semicarbazide,1,1-dimethyl-4-(o-(methoxycarbonyl)phenyl)-3-thio、1,1-Dimethyl-4-(o-(methoxycarbonyl)phenyl)-3-thiosemicarbazide、methyl 2-(3-fluoro-4-(methylcarbamoyl)phenylamino)-2-methylpropanoate
CAS号
1332524-01-2
分子式
C13H17FN2O3
分子量
268.284
精确质量
268.122
PSA
70.92
LOGP
2.1966
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