百科

(3S,4aS,8aS)-

CAS号：142580-65-2

英文名：tert-butyl N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate

分子式

C29H47N3O4

熔点

密度

1.082g/cm3

分子量

501.701

沸点

680.5ºC at 760mmHg

溶解度

信号词

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化合物简介

Intermediate in the preparation of HIV-1 protease inhibitors.

基本信息

中文名称

(3S,4aS,8aS)-

英文名称

tert-butyl N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate

中文别名

英文别名

CAS号

142580-65-2

分子式

C29H47N3O4

分子量

501.701

精确质量

501.357

PSA

97.88

LOGP

5.2613

物化性质

密度

1.082g/cm3

沸点

680.5ºC at 760mmHg

闪点

365.4ºC

折射率

1.528

蒸汽压

1.88E-19mmHg at 25°C

合成路线

共找到3条合成路线 >

98760-08-8

(1S)-1-(2R)-环氧乙基-2-苯乙基氨基甲酸叔丁酯

128019-40-9

[3S-(3α,4αβ,8αβ)]-N-(tert-butyl)decahydro-3-isoquinolinecarboxamide

上游原料

(2S,3S)-1-bromo-3-((tert-butoxycarbonyl)amino)-4-phenyl-2-butanol

152683-74-4

3(S)-(tert-Butoxyformamido)-2(S)-hydroxy-4-phenyl-1-butanal

13734-34-4

BOC-L-苯丙氨酸

128019-40-9

[3S-(3α,4αβ,8αβ)]-N-(tert-butyl)decahydro-3-isoquinolinecarboxamide

24424-99-5

二碳酸二叔丁酯

136630-89-2

(4S,5S)-4-benzyl-5-(bromomethyl)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine

下游产品

共找到3个下游商品 >

136522-17-3

(3S,4a,8aS)-2-[(2R,3S)-3-氨基-2-羟基-4-苯基丁基]-N-叔丁基十氢异喹啉-3-甲酰胺

136522-18-4

benzyl N-[(2S)-1-[[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]amino]-4-amino-1,4-dioxobutan-2-yl]carbamate

127779-20-8

沙喹那韦

上游原料

(2S,3S)-1-bromo-3-((tert-butoxycarbonyl)amino)-4-phenyl-2-butanol 3(S)-(tert-Butoxyformamido)-2(S)-hydroxy-4-phenyl-1-butanal BOC-L-苯丙氨酸 [3S-(3α,4αβ,8αβ)]-N-(tert-butyl)decahydro-3-isoquinolinecarboxamide 二碳酸二叔丁酯 (4S,5S)-4-benzyl-5-(bromomethyl)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine (4S,5S)-4-benzyl-5-benzyloxymethyl-1,3-oxazolidin-2-one (3S,4aS,8aS)-2-(叔丁氧羰基)十氢异喹啉-3-羧酸 (1S,2S)-2-((tert-butoxycarbonyl)amino)-3-phenyl-1-(thiazol-2-yl)propyl acetate tert-butyl (3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinoline-2(1H)-carboxylate (S,S)-2-(2-(N-(tert-Butoxycarbonyl)amino)-1-hydroxy-3-phenylpropyl)-1,3-thiazole 4(S)-Benzyl-3-(tert-butoxycarbonyl)-2,2-dimethyl-5(R)-oxazolidineacetic acid Ethyl 4(S)-benzyl-3-(tert-butoxycarbonyl)-2,2-dimethyl-5(R)-oxazolidineacetate (2S,3S)-3-amino-1-(benzyloxy)-4-phenylbutan-2-ol tert-butyl ((2S,3S)-4-(benzyloxy)-3-hydroxy-1-phenylbutan-2-yl)carbamate N-(tert-butoxycarbonyl)-4(S)-amino-3(R)-hydroxy-5-phenylpentanoic acid ethyl ester 2-甲基-2-丙基(3,4-二羟基-1-苯基-2-丁烷基)氨基甲酸酯 4(S)-Benzyl-3-(tert-butoxycarbonyl)-2,2-dimethyl-5(R)-oxazolidineacetic acid chloride (1S)-1-(2R)-环氧乙基-2-苯乙基氨基甲酸叔丁酯 N-Boc-L-苯丙氨醛 N-Boc-β-keto-γ-phenylalanine 2-(2(S)-(tert-Butoxyformamido)-1-hydroxy-3-phenylpropyl)thiazole

下游产品

(3S,4a,8aS)-2-[(2R,3S)-3-氨基-2-羟基-4-苯基丁基]-N-叔丁基十氢异喹啉-3-甲酰胺 benzyl N-[(2S)-1-[[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]amino]-4-amino-1,4-dioxobutan-2-yl]carbamate 沙喹那韦