1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS号：1445379-88-3

英文名：1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

分子式

C32H44ClFN2O5Si2

熔点

密度

分子量

647.325

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

英文名称

1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

中文别名

英文别名

CAS号

1445379-88-3

分子式

C32H44ClFN2O5Si2

分子量

647.325

精确质量

646.246

PSA

82.55

LOGP

5.3481

合成路线

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2'-氟-2'-脱氧尿苷

2'-氟-2'-脱氧尿苷

1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(chloromethyl)-3-fluorotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

上游原料

共找到1个上游原料 >

2'-氟-2'-脱氧尿苷

2'-氟-2'-脱氧尿苷

下游产品

共找到14个下游商品 >

(2R,3R,4R,5R)-5-(4-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-2-oxopyrimidin-1(2H)-yl)-2-(chloromethyl)-4-fluoro-2-((hexanoyloxy)methyl)tetrahydrofuran-3-yl hexanoate

(2R,3R,4R,5R)-5-(4-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-2-oxopyrimidin-1(2H)-yl)-2-(chloromethyl)-4-fluoro-2-((hexanoyloxy)methyl)tetrahydrofuran-3-yl hexanoate

4'-chloromethyl-2'-deoxy-2'-fluoro-3'-O-octanoylcytidine

4'-chloromethyl-2'-deoxy-2'-fluoro-3'-O-octanoylcytidine

4'-chloromethyl-2'-deoxy-3',5'-di-O-propionyl-2'-fluorocytidine

4'-chloromethyl-2'-deoxy-3',5'-di-O-propionyl-2'-fluorocytidine

((2R,3R,4R,5R)-3-(benzoyloxy)-2-(chloromethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R,5R)-3-(benzoyloxy)-2-(chloromethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl benzoate

4'-chloromethyl-2'-deoxy-3',5'-di-O-hexanoyl-2'-fluorocytidine

4'-chloromethyl-2'-deoxy-3',5'-di-O-hexanoyl-2'-fluorocytidine

4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine

4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine

上游原料

2'-氟-2'-脱氧尿苷

下游产品

(2R,3R,4R,5R)-5-(4-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-2-oxopyrimidin-1(2H)-yl)-2-(chloromethyl)-4-fluoro-2-((hexanoyloxy)methyl)tetrahydrofuran-3-yl hexanoate 4'-chloromethyl-2'-deoxy-2'-fluoro-3'-O-octanoylcytidine 4'-chloromethyl-2'-deoxy-3',5'-di-O-propionyl-2'-fluorocytidine ((2R,3R,4R,5R)-3-(benzoyloxy)-2-(chloromethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl benzoate 4'-chloromethyl-2'-deoxy-3',5'-di-O-hexanoyl-2'-fluorocytidine 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine 4'-chloromethyl-2'-deoxy-2'-fluoro-5'-O-octanoylcytidine 4'-chloromethyl-2'-deoxy-3',5'-di-O-octanoyl-2'-fluorocytidine ((2R,3R,4R,5R)-3-acetoxy-2-(chloromethyl)-4-fluoro-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate ((2R,3R,4R,5R)-3-acetoxy-2-(chloromethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl acetate ((2R,3R,4R,5R)-3-acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(chloromethyl)-4-fluorotetrahydrofuran-2-yl)methyl acetate 4-amino-1-((2R,3R,4R,5R)-5-(chloromethyl)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one ((2R,3R,4R,5R)-3-(benzoyloxy)-2-(chloromethyl)-4-fluoro-5-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate 4'-chloromethyl-2'-deoxy-3',5'-di-O-pentanoyl-2'-fluorocytidine