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8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

CAS号：1449278-53-8

英文名：8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

分子式

C15H10FN3O2

熔点

密度

分子量

283.257

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

英文名称

8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

中文别名

英文别名

CAS号

1449278-53-8

分子式

C15H10FN3O2

分子量

283.257

精确质量

283.076

PSA

89.1

LOGP

3.2975

合成路线

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5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one

8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid

上游原料

共找到7个上游原料 >

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one

ethyl 2-(3-fluorophenyl)-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate

ethyl 8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

ethyl 1-oxido-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-1-ium-5-carboxylate

ethyl 1-oxido-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-1-ium-5-carboxylate

下游产品

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8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide trifluoroacetate

8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide trifluoroacetate

8-amino-N-(1-(1,1-dioxidothiomorpholine-4-carbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

8-amino-N-(1-(1,1-dioxidothiomorpholine-4-carbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)cyclopropanecarboxamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)cyclopropanecarboxamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)-N-(cyclopropanecarbonyl)cyclopropanecarboxamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)-N-(cyclopropanecarbonyl)cyclopropanecarboxamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)acetamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)acetamide

N-(1-acetylazetidin-3-yl)-8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

N-(1-acetylazetidin-3-yl)-8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

上游原料

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one ethyl 2-(3-fluorophenyl)-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate ethyl 8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate ethyl 1-oxido-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-1-ium-5-carboxylate ethyl 2-chloro-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

下游产品

8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide trifluoroacetate 8-amino-N-(1-(1,1-dioxidothiomorpholine-4-carbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)cyclopropanecarboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)-N-(cyclopropanecarbonyl)cyclopropanecarboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)acetamide N-(1-acetylazetidin-3-yl)-8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-5-iodo-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-(morpholine-4-carbonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-N-methyl-1,7-naphthyridine-5-carboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)propionamide 2-(3-fluorophenyl)-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-((trifluoromethyl)sulfonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide (R)-8-amino-2-(3-fluorophenyl)-N-(1-(2-hydroxypropanoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide (S)-8-amino-2-(3-fluorophenyl)-N-(1-(2-hydroxypropanoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-N-methyl-1,7-naphthyridin-5-carboxamide 2-(3-fluorophenyl)-5-(1H-1,2,4-triazol-5-yl)-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-(2-morpholinoacetyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-sulfamoylazetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-(2-hydroxypropanoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-(oxetane-3-carbonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-5-(1-(2-morpholinoethyl)-1H-imidazol-4-yl)-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-(2-methoxyacetyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide (8-amino-2-(3-fluorophenyl)-1,7-naphthyridin-5-yl)(3-aminoazetidin-1-yl)methanone