化合物简介
Talnetant (SB-223,412) is a neurokinin 3 receptor antagonist developed by GlaxoSmithKline, which is being researched for several different functions, primarily for irritable bowel syndrome however its use as a potential antipsychotic drug for the treatment of schizophrenia has been discontinued.
基本信息
中文名称
(-)-(S)-N-(alpha-乙基苄基)-3-羟基-2-苯基喹啉-4-羧酰胺
英文名称
3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
中文别名
英文别名
Talnetant、(S)-N-(1-Phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide,SB-223412、UNII-CZ3T9T146K
CAS号
174636-32-9
分子式
C25H22N2O2
分子量
382.454
精确质量
382.168
PSA
65.71
LOGP
6.0633
编号系统
UNII
CZ3T9T146K
物化性质
密度
1.212g/cm3
沸点
580.4ºC at 760mmHg
闪点
304.8ºC
折射率
1.657
蒸汽压
4.51E-14mmHg at 25°C
