百科

(R)-N-[3-(3-氟-(4-吗啉基)苯基)-2-氧代-5-噁唑烷基]甲醇甲磺酸酯

CAS号：174649-09-3

英文名：(R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

分子式

C15H19FN2O6S

熔点

183-185ºC

密度

1.418

分子量

374.385

沸点

溶解度

信号词

危险品标志

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化合物简介

(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone is an intermediate in the synthesis of Linezolid Dimer, an impurity of the antibacterial agent Linezolid.

基本信息

中文名称

(R)-N-[3-(3-氟-(4-吗啉基)苯基)-2-氧代-5-噁唑烷基]甲醇甲磺酸酯

英文名称

(R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

中文别名

(R)-[3-(3-氟-4-吗啉苯基)-2-氧-5-噁唑烷基]甲醇甲磺酸酯

英文别名

[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl methanesulfonate

CAS号

174649-09-3

分子式

C15H19FN2O6S

分子量

374.385

精确质量

374.095

PSA

93.76

LOGP

2.1745

编号系统

MDL号

MFCD18070719

物化性质

密度

1.418

熔点

183-185ºC

安全信息

海关编码

2934999090

合成路线

(5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮

174649-09-3

(R)-N-[3-(3-氟-(4-吗啉基)苯基)-2-氧代-5-噁唑烷基]甲醇甲磺酸酯

上游原料

benzyl (S)-(2,3-dihydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamate

93246-53-8

3-氟-4-(4-吗啉基)苯胺

239438-43-8

(5R,5'R)-5,5'-((1S,2S)-1,2-dihydroxyethane-1,2-diyl)bis(3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one)

868405-66-7

N-[3-chloro-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholin-4-yl)aniline

下游产品

共找到4个下游商品 >

168828-89-5

(S)-[N-3-(3'-氟-4'-吗啉基)苯基-2-氧代-5-噁唑烷

上游原料

3,4-二氟硝基苯 4-(2-氟-4-硝基苯基)吗啉 benzyl (S)-(2,3-dihydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamate 3-氟-4-(4-吗啉基)苯胺 (5R,5'R)-5,5'-((1S,2S)-1,2-dihydroxyethane-1,2-diyl)bis(3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one) N-[3-chloro-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholin-4-yl)aniline (5R,5'R)-5,5'-((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one) (3-Fluoro-4-morpholin-4-yl-phenyl)-(3-oxo-propyl)-carbamic acid benzyl ester 甲烷磺酰氯 benzyl (3-fluoro-4-morpholinophenyl)(3-hydroxypropyl)carbamate (R)-2-(3-Fluoro-4-morpholin-4-yl-phenylamino)-1-{(4R,5R)-5-[(R)-2-(3-fluoro-4-morpholin-4-yl-phenylamino)-1-hydroxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-ethanol (3-氟-4-吗啉-4-基苯基)氨基甲酸苄酯 3-氟-4-吗啉苯基氨基甲酸乙酯 (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮

下游产品

(S)-[N-3-(3'-氟-4'-吗啉基)苯基-2-氧代-5-噁唑烷吗啉恶酮相关物质A 利奈唑胺利奈唑胺碱