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埃博霉素C

埃博霉素C

CAS号:186692-73-9
英文名:4,8-dihydroxy-5,5,7,9-tetramethyl-16-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione
分子式:C27H41NO5S
分子量:491.683
上游原料
(Z)-(4S,7R,8S,9S,16S)-4-(tert-Butyl-dimethyl-silanyloxy)-8-hydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclohexadec-13-ene-2,6-dione (2E)-2-Methyl-3-(2-methyl-1,3-thiazol-4-yl)acrylaldehyde (2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol (4S,5S)-4-Hydroxy-5-methyl-tetrahydro-pyran-2-one (-)-(3S)-3-(tert-butyldimethylsilyl)oxy-4,4-dimethyl-5-oxoheptanoic acid (4S,7R,8S,9S,16S,Z)-8-((tert-butyldimethylsilyl)oxy)-4-((4-methoxybenzyl)oxy)-5,5,7,9-tetramethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione 2-[(2R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-1,1,3,5-tetramethyl-2-triphenylsilanyloxy-dec-9-enyl]-[1,3]dithiane (3S,6R,7S,8S,12Z,15S,16E)-3,7-bis(tert-butyldimethylsilyloxy)-15-hydroxy-4,4,6,8,16-pentamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxo-heptadeca-12,16-dienoic acid (S)-2-(methoxymethoxy)-5-(trimethylsilyl)pent-4-ynal (3R,4R,5S)-3-(2-(1,3-dithian-2-yl)propan-2-yl)-5-((S)-1-(benzyloxy)propan-2-yl)-4,7,7,8,8-pentamethyl-1,1,1-triphenyl-2,6-dioxa-1,7-disilanonane (3R,4R,5S,6S)-6-((S)-1-(benzyloxy)propan-2-yl)-3-(iodomethyl)-2-methoxy-3,5-dimethyltetrahydro-2H-pyran-4-ol (2S)-1-((tetrahydro-2H-pyran-2-yl)oxy)-5-(trimethylsilyl)pent-4-yn-2-ol (1S)-1-[(E)-1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-ethenyl]-3-butenyl (3S,6R,7S,8S)-3,7-di-[tert-butyldimethylsilyloxy]-4,4,6,8-tetramethyl-5-oxo-12-tridecenoate (4S,7R,8S,9S,16S)-4,8-bis-(tert-butyldimethylsilanyloxy)-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-vinyl]-(13Z)-1-oxacyclohexadec-13-ene-2,6-dione (1S)-[(1E)-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethynyl]-3-butenyl acetate 2-甲基-1,3-噻唑-4-甲醛 (1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol (4S,5S)-5-methyltetrahydro-2H-pyran-2,4-diol (2R,3S,4S)-3-((4-methoxybenzyl)oxy)-2,4-dimethylhept-6-enal (6S,7S,8R,9R)-7-(tert-Butyl-dimethyl-silanyloxy)-10-[1,3]dithian-2-yl-6,8,10-trimethyl-9-triphenylsilanyloxy-undec-1-en-5-ol (1E,3S)-3-(tert-butyldimethylsilyloxy)-2-methyl-6-trimethylsilyl-1-(2-methyl-1,3-thiazol-4-yl)-1-hexen-5-yne (1E,3Z)-1-甲氧基-2-甲基-3-(三甲基硅氧基)-1,3-戊二烯 (2R,3E)-ethyl 2-hydroxy-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenoate (2R,3E)-2-(tert-butyldimethylsilyloxy)-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenal (4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-ol 2-甲基噻唑-4-甲酸乙酯 (2S,3S,4R,5R)-1-(benzyloxy)-6-(1,3-dithian-2-yl)-2,4,6-trimethyl-5-((triphenylsilyl)oxy)heptan-3-ol (4S,5S)-2-(4-methoxyphenyl)-5-methyl-4-((S)-pent-4-en-2-yl)-1,3-dioxane (S,E)-2-methyl-1-(2-methylthiazol-4-yl)hexa-1,5-dien-3-yl (3R,5R,6R,7S,8S)-7-((tert-butyldimethylsilyl)oxy)-3-hydroxy-4,4,6,8-tetramethyl-5-((triphenylsilyl)oxy)tridec-12-enoate (3S,6R,7S,8S)-(S,E)-2-methyl-1-(2-methylthiazol-4-yl)hexa-1,5-dien-3-yl 3-((tert-butyldimethylsilyl)oxy)-7-hydroxy-4,4,6,8-tetramethyl-5-oxotridec-12-enoate (3S)-2-methyl-1-(2-methyl-1,3-thiazol-4-yl)hexa-1,5-dien-3-ol methyl (S)-2-((1R,2S)-1,3-dihydroxy-2-methylpropyl)pent-4-enoate (3S)-3-(methoxymethoxy)-6-(trimethylsilyl)hex-5-yn-2-ol (3S,6R,7S,8S,12Z,15S,16E)-3,7,15-tris(tert-butyldimethylsilyloxy)-4,4,6,8,16-pentamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxo-heptadeca-12,16-dienoic acid [(S)-4-Methoxymethoxy-5-(tetrahydro-pyran-2-yloxy)-pent-1-ynyl]-trimethyl-silane (2R,3R,4R,5R)-3-((tert-butyldimethylsilyl)oxy)-6-(1,3-dithian-2-yl)-2,4,6-trimethyl-5-((triphenylsilyl)oxy)heptanal (2S,3S,4R)-2-((S)-1-(benzyloxy)propan-2-yl)-3,5-dimethyl-3,4-dihydro-2H-pyran-4-ol (1E,3S,5Z)-2-methyl-6-trimethylsilyl-1-(2-methyl-1,3-thiazol-4-yl)-1,5-hexadien-3-ol (2R,3E)-ethyl 2-(tert-butyldimethylsilyloxy)-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenoate Carbonic acid (E)-(R)-2-(tert-butyl-dimethyl-silanyloxy)-3-methyl-4-(2-methyl-thiazol-4-yl)-1-trimethylsilanylethynyl-but-3-enyl ester methyl ester (2R,3E)-2-hydroxy-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenenitrile [(4R,5R,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-yloxy]-triphenyl-silane 西洛他唑 (S)-2-Methoxymethoxy-5-trimethylsilanyl-pent-4-yn-1-ol (1E,3S,5Z)-2-methyl-6-iodo-1-(2-methyl-1,3-thiazol-4-yl)-1,5-hexadien-3-yl acetate