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埃博霉素C

埃博霉素C

CAS号：186692-73-9

英文名：4,8-dihydroxy-5,5,7,9-tetramethyl-16-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

分子式

C27H41NO5S

熔点

密度

分子量

491.683

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

埃博霉素C

英文名称

4,8-dihydroxy-5,5,7,9-tetramethyl-16-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

中文别名

埃博霉素 C

英文别名

12,13-deoxyepothilone A、desoxyepothilone A、(4R,7S,8R,9S,13E,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione、(4S,7R,8S,9S,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-vinyl]-(13Z)-1-oxacyclohexadec-13-ene-2,6-dione、(4S,78S,9S,13Z,16S)-4,8-DIHYDROXY-5,5,7,9-TETRAMETHYL-16-[(1E)-1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-OXACYCLOHEXADEC-13-ENE-2,6-DIONE、Epothilone C、(4S,7R,8S,9S,16S)-4,8-Dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-ethenyl]-1-oxa-cyclohexadecen-(13Z)-en-2,6-dione、deoxyepothilone A、Z-epothilone C

CAS号

186692-73-9

分子式

C27H41NO5S

分子量

491.683

精确质量

491.271

PSA

124.96

LOGP

5.2663

编号系统

UNII

18T00XLN7E

合成路线

共找到2条合成路线 >

(4S,7R,8S,9S,16S)-4,8-bis-(tert-butyldimethylsilanyloxy)-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-vinyl]-(13Z)-1-oxacyclohexadec-13-ene-2,6-dione

(4S,7R,8S,9S,16S)-4,8-bis-(tert-butyldimethylsilanyloxy)-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-vinyl]-(13Z)-1-oxacyclohexadec-13-ene-2,6-dione

埃博霉素C

上游原料

共找到171个上游原料 >

(Z)-(4S,7R,8S,9S,16S)-4-(tert-Butyl-dimethyl-silanyloxy)-8-hydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclohexadec-13-ene-2,6-dione

(Z)-(4S,7R,8S,9S,16S)-4-(tert-Butyl-dimethyl-silanyloxy)-8-hydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclohexadec-13-ene-2,6-dione

(2E)-2-Methyl-3-(2-methyl-1,3-thiazol-4-yl)acrylaldehyde

(2E)-2-Methyl-3-(2-methyl-1,3-thiazol-4-yl)acrylaldehyde

(2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol

(2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol

(4S,5S)-4-Hydroxy-5-methyl-tetrahydro-pyran-2-one

(4S,5S)-4-Hydroxy-5-methyl-tetrahydro-pyran-2-one

(-)-(3S)-3-(tert-butyldimethylsilyl)oxy-4,4-dimethyl-5-oxoheptanoic acid

(-)-(3S)-3-(tert-butyldimethylsilyl)oxy-4,4-dimethyl-5-oxoheptanoic acid

(4S,7R,8S,9S,16S,Z)-8-((tert-butyldimethylsilyl)oxy)-4-((4-methoxybenzyl)oxy)-5,5,7,9-tetramethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione

(4S,7R,8S,9S,16S,Z)-8-((tert-butyldimethylsilyl)oxy)-4-((4-methoxybenzyl)oxy)-5,5,7,9-tetramethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione

下游产品

共找到2个下游商品 >

西洛他唑

[1R,3S,7S,10R,11S,12S,16S]-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-[2-methylthiazol-4-yl]prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

[1R,3S,7S,10R,11S,12S,16S]-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-[2-methylthiazol-4-yl]prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

上游原料

(Z)-(4S,7R,8S,9S,16S)-4-(tert-Butyl-dimethyl-silanyloxy)-8-hydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclohexadec-13-ene-2,6-dione (2E)-2-Methyl-3-(2-methyl-1,3-thiazol-4-yl)acrylaldehyde (2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol (4S,5S)-4-Hydroxy-5-methyl-tetrahydro-pyran-2-one (-)-(3S)-3-(tert-butyldimethylsilyl)oxy-4,4-dimethyl-5-oxoheptanoic acid (4S,7R,8S,9S,16S,Z)-8-((tert-butyldimethylsilyl)oxy)-4-((4-methoxybenzyl)oxy)-5,5,7,9-tetramethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione 2-[(2R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-1,1,3,5-tetramethyl-2-triphenylsilanyloxy-dec-9-enyl]-[1,3]dithiane (3S,6R,7S,8S,12Z,15S,16E)-3,7-bis(tert-butyldimethylsilyloxy)-15-hydroxy-4,4,6,8,16-pentamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxo-heptadeca-12,16-dienoic acid (S)-2-(methoxymethoxy)-5-(trimethylsilyl)pent-4-ynal (3R,4R,5S)-3-(2-(1,3-dithian-2-yl)propan-2-yl)-5-((S)-1-(benzyloxy)propan-2-yl)-4,7,7,8,8-pentamethyl-1,1,1-triphenyl-2,6-dioxa-1,7-disilanonane (3R,4R,5S,6S)-6-((S)-1-(benzyloxy)propan-2-yl)-3-(iodomethyl)-2-methoxy-3,5-dimethyltetrahydro-2H-pyran-4-ol (2S)-1-((tetrahydro-2H-pyran-2-yl)oxy)-5-(trimethylsilyl)pent-4-yn-2-ol (1S)-1-[(E)-1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-ethenyl]-3-butenyl (3S,6R,7S,8S)-3,7-di-[tert-butyldimethylsilyloxy]-4,4,6,8-tetramethyl-5-oxo-12-tridecenoate (4S,7R,8S,9S,16S)-4,8-bis-(tert-butyldimethylsilanyloxy)-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-vinyl]-(13Z)-1-oxacyclohexadec-13-ene-2,6-dione (1S)-[(1E)-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethynyl]-3-butenyl acetate 2-甲基-1,3-噻唑-4-甲醛 (1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol (4S,5S)-5-methyltetrahydro-2H-pyran-2,4-diol (2R,3S,4S)-3-((4-methoxybenzyl)oxy)-2,4-dimethylhept-6-enal (6S,7S,8R,9R)-7-(tert-Butyl-dimethyl-silanyloxy)-10-[1,3]dithian-2-yl-6,8,10-trimethyl-9-triphenylsilanyloxy-undec-1-en-5-ol (1E,3S)-3-(tert-butyldimethylsilyloxy)-2-methyl-6-trimethylsilyl-1-(2-methyl-1,3-thiazol-4-yl)-1-hexen-5-yne (1E,3Z)-1-甲氧基-2-甲基-3-(三甲基硅氧基)-1,3-戊二烯 (2R,3E)-ethyl 2-hydroxy-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenoate (2R,3E)-2-(tert-butyldimethylsilyloxy)-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenal (4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-ol 2-甲基噻唑-4-甲酸乙酯 (2S,3S,4R,5R)-1-(benzyloxy)-6-(1,3-dithian-2-yl)-2,4,6-trimethyl-5-((triphenylsilyl)oxy)heptan-3-ol (4S,5S)-2-(4-methoxyphenyl)-5-methyl-4-((S)-pent-4-en-2-yl)-1,3-dioxane (S,E)-2-methyl-1-(2-methylthiazol-4-yl)hexa-1,5-dien-3-yl (3R,5R,6R,7S,8S)-7-((tert-butyldimethylsilyl)oxy)-3-hydroxy-4,4,6,8-tetramethyl-5-((triphenylsilyl)oxy)tridec-12-enoate (3S,6R,7S,8S)-(S,E)-2-methyl-1-(2-methylthiazol-4-yl)hexa-1,5-dien-3-yl 3-((tert-butyldimethylsilyl)oxy)-7-hydroxy-4,4,6,8-tetramethyl-5-oxotridec-12-enoate (3S)-2-methyl-1-(2-methyl-1,3-thiazol-4-yl)hexa-1,5-dien-3-ol methyl (S)-2-((1R,2S)-1,3-dihydroxy-2-methylpropyl)pent-4-enoate (3S)-3-(methoxymethoxy)-6-(trimethylsilyl)hex-5-yn-2-ol (3S,6R,7S,8S,12Z,15S,16E)-3,7,15-tris(tert-butyldimethylsilyloxy)-4,4,6,8,16-pentamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxo-heptadeca-12,16-dienoic acid [(S)-4-Methoxymethoxy-5-(tetrahydro-pyran-2-yloxy)-pent-1-ynyl]-trimethyl-silane (2R,3R,4R,5R)-3-((tert-butyldimethylsilyl)oxy)-6-(1,3-dithian-2-yl)-2,4,6-trimethyl-5-((triphenylsilyl)oxy)heptanal (2S,3S,4R)-2-((S)-1-(benzyloxy)propan-2-yl)-3,5-dimethyl-3,4-dihydro-2H-pyran-4-ol (1E,3S,5Z)-2-methyl-6-trimethylsilyl-1-(2-methyl-1,3-thiazol-4-yl)-1,5-hexadien-3-ol (2R,3E)-ethyl 2-(tert-butyldimethylsilyloxy)-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenoate Carbonic acid (E)-(R)-2-(tert-butyl-dimethyl-silanyloxy)-3-methyl-4-(2-methyl-thiazol-4-yl)-1-trimethylsilanylethynyl-but-3-enyl ester methyl ester (2R,3E)-2-hydroxy-3-methyl-4-(2-methyl-1,3-thiazol-4-yl)-3-butenenitrile [(4R,5R,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-yloxy]-triphenyl-silane 西洛他唑 (S)-2-Methoxymethoxy-5-trimethylsilanyl-pent-4-yn-1-ol (1E,3S,5Z)-2-methyl-6-iodo-1-(2-methyl-1,3-thiazol-4-yl)-1,5-hexadien-3-yl acetate

下游产品

西洛他唑 [1R,3S,7S,10R,11S,12S,16S]-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-[2-methylthiazol-4-yl]prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione