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羟基喜树碱

羟基喜树碱

CAS号：19685-09-7

英文名：10-Hydroxycamptothecin

分子式

C20H16N2O5

熔点

密度

分子量

364.351

沸点

溶解度

信号词

危险品标志

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化合物简介

A Camptothecin derivative; a topoisomerase inhibitor for cancer therapy.

基本信息

中文名称

羟基喜树碱

英文名称

10-Hydroxycamptothecin

中文别名

伊立替康相关物质A、(S)-10-羟基喜树碱、10-羟基喜树碱

英文别名

Hydroxycamptothecine、Irinotecan Related Compound A、Camptothecin,hydroxy、Hydroxycamptothecin、10-Hydroxy camptothecin、10-OH-camptothecin、10-hydroxycamptothecine、HCPT、10-hydroxy-CPT、10-Hydroxycamptochecin

CAS号

19685-09-7

分子式

C20H16N2O5

分子量

364.351

精确质量

364.106

PSA

101.65

LOGP

1.7852

安全信息

海关编码

2934999090

生产方法及用途

用途

抗肿瘤药。

合成路线

共找到15条合成路线 >

托泊替康醋酸盐; 醋酸拓扑替康; 4-乙基-4,9-二羟基-10-[(二甲基氨基)甲基]-1H-吡喃并[3',4':6,7]中氮茚并[1,2-b]喹啉-3,14(4H,12H)-二酮醋酸盐

托泊替康醋酸盐; 醋酸拓扑替康; 4-乙基-4,9-二羟基-10-[(二甲基氨基)甲基]-1H-吡喃并[3',4':6,7]中氮茚并[1,2-b]喹啉-3,14(4H,12H)-二酮醋酸盐

(S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-12-methylene-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

(S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-12-methylene-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

羟基喜树碱

羟基喜树碱

拓普替康

喜树碱

上游原料

共找到35个上游原料 >

4-iodo-2-methoxy-6-trimethylsilanyl-3-pyridinecarboxaldehyde

4-iodo-2-methoxy-6-trimethylsilanyl-3-pyridinecarboxaldehyde

10-氨基喜树碱

10-氨基喜树碱

1-benzyl 3-methyl 2-(2,2-dimethoxyethylidene)malonate

1-benzyl 3-methyl 2-(2,2-dimethoxyethylidene)malonate

(S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone

(S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone

9-硝基喜树碱

9-硝基喜树碱

(S)-4-ethyl-4-hydroxy-6-iodo-8-methoxy-1,4-dihydro-pyrano[3,4-c]pyridin-3-one

(S)-4-ethyl-4-hydroxy-6-iodo-8-methoxy-1,4-dihydro-pyrano[3,4-c]pyridin-3-one

下游产品

共找到7个下游商品 >

拓普替康

7-乙基-10-羟基喜树碱

7-乙基-10-羟基喜树碱

拓扑替康

9-氮-10-羟基喜树碱

9-氮-10-羟基喜树碱

鲁比替康

9-氨基喜树碱

9-氨基喜树碱

上游原料

4-iodo-2-methoxy-6-trimethylsilanyl-3-pyridinecarboxaldehyde 10-氨基喜树碱 1-benzyl 3-methyl 2-(2,2-dimethoxyethylidene)malonate (S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone 9-硝基喜树碱 (S)-4-ethyl-4-hydroxy-6-iodo-8-methoxy-1,4-dihydro-pyrano[3,4-c]pyridin-3-one 喜树碱氮氧化物 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-(3-(hydroxymethyl)-2-methoxypyridin-4-yl)propan-1-ol 2-甲氧基-6-(三甲基硅烷基)吡啶巯基乙酸乙酯 4-ethyl-8-methoxy-6-(trimethylsilyl)-1H-pyrano[3,4-c]pyridine 4-((S)-1-(benzyloxy)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-propyl)-3-((benzyloxy)methyl)-2-methoxypyridine (S)-(+)-4-ethyl-4-hydroxy-8-methoxy-6-(trimethylsilyl)-1,4-dihydro-3H-pyrano[3,4-c]pyridin-3-one 喜树碱 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-ethyl-4-methoxyfuro[3,4-c]pyridin-3(1H)-one 2-methoxy-6-(trimethylsilyl)nicotinaldehyde (S)-4-ethyl-4-hydroxy-8-methoxy-1H-pyrano[3,4-c]pyridin-3(4H)-one 4-hydroxyphenyl isocyanide 2-甲氧基烟酸醋酸 4-ethyl-4-hydroxy-1,5b,6,11,11a,12-hexahydro-4H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione methyl 7-methoxy-1,3-dihydro-2H-pyrrolo[3,4-b]quinoline-2-carboxylate (S)-4-Ethyl-4-hydroxy-6-iodo-3-oxo-7-propargyl-1H-pyrano[3,4-c]-8-pyridone (S)-2-(benzyloxy)-2-(3-((benzyloxy)methyl)-2-methoxypyridin-4-yl)butanoic acid (4R,5bS,11aS)-4-ethyl-4-hydroxy-9-nitro-1,5b,6,11,11a,12-hexahydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione (S)-2-(benzyloxy)-2-(3-((benzyloxy)methyl)-2-methoxypyridin-4-yl)butanal (4S)-4-乙基-4-羟基-1H-吡喃并[3,4-c]吡啶-3,8(4h,7h)-二酮 (+/-)-4-ethyl-4-hydroxy-8-methoxy-6-(trimethylsilyl)-1,4-dihydro-3H-pyrano[3,4-c]pyridin-3-one 托泊替康醋酸盐; 醋酸拓扑替康; 4-乙基-4,9-二羟基-10-[(二甲基氨基)甲基]-1H-吡喃并[3',4':6,7]中氮茚并[1,2-b]喹啉-3,14(4H,12H)-二酮醋酸盐 1,2,6,7-tetrahydro-(20S)-camphthotecine methyl 7-((2R,4S)-2-(tert-butyl)-4-ethyl-5-oxo-1,3-dioxolan-4-yl)-2-methoxy-9-oxo-9,11-dihydroindolizino[1,2-b]quinoline-8-carboxylate 9-甲氧基喜树碱甲醇 (2R,3S)-3-(benzyloxy)-3-(3-((benzyloxy)methyl)-2-methoxypyridin-4-yl)pentane-1,2-diol 10-[4-(β-D-glucuronyloxy)-3-nitrobenzyloxy]camptothecin

下游产品

拓普替康 7-乙基-10-羟基喜树碱拓扑替康 9-氮-10-羟基喜树碱鲁比替康 9-氨基喜树碱 9-甲氧基喜树碱