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(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

CAS号：197233-36-6

英文名：(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

分子式

C53H75NO5SSi2

熔点

密度

分子量

894.402

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

英文名称

(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

中文别名

英文别名

CAS号

197233-36-6

分子式

C53H75NO5SSi2

分子量

894.402

精确质量

893.49

PSA

106.12

LOGP

11.5812

合成路线

共找到3条合成路线 >

(1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol

(1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol

(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

(3R,5R,6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-4,4,6,8,12-pentamethyl-5-triphenylsilanyloxy-tridec-12-enoic acid (S)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-but-3-enyl ester

上游原料

共找到5个上游原料 >

[(4R,5R,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-yloxy]-triphenyl-silane

[(4R,5R,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-yloxy]-triphenyl-silane

(2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol

(2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol

(1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol

(1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol

(6S,7S,8R,9R)-7-(tert-Butyl-dimethyl-silanyloxy)-10-[1,3]dithian-2-yl-2,6,8,10-tetramethyl-9-triphenylsilanyloxy-undec-1-en-5-ol

(6S,7S,8R,9R)-7-(tert-Butyl-dimethyl-silanyloxy)-10-[1,3]dithian-2-yl-2,6,8,10-tetramethyl-9-triphenylsilanyloxy-undec-1-en-5-ol

(4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-ol

(4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-ol

下游产品

共找到3个下游商品 >

埃博霉素B

(1S)-1-[(E)-1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-ethenyl]-3-butenyl (3S,6R,7S,8S)-3,7-di-[tert-butyldimethylsilyloxy]-4,4,6,8,12-pentamethyl-5-oxo-12-tridecenoate

(1S)-1-[(E)-1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-ethenyl]-3-butenyl (3S,6R,7S,8S)-3,7-di-[tert-butyldimethylsilyloxy]-4,4,6,8,12-pentamethyl-5-oxo-12-tridecenoate

Epothilone D

上游原料

[(4R,5R,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-yloxy]-triphenyl-silane (2S,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-6-[1,3]dithian-2-yl-2,4,6-trimethyl-5-triphenylsilanyloxy-heptan-1-ol (1R,3S,4S,5R,6R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-4,6-dimethyl-2-oxa-bicyclo[4.1.0]heptan-5-ol (6S,7S,8R,9R)-7-(tert-Butyl-dimethyl-silanyloxy)-10-[1,3]dithian-2-yl-2,6,8,10-tetramethyl-9-triphenylsilanyloxy-undec-1-en-5-ol (4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methoxy-3,3,5-trimethyl-tetrahydro-pyran-4-ol

下游产品

埃博霉素B (1S)-1-[(E)-1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)-1-ethenyl]-3-butenyl (3S,6R,7S,8S)-3,7-di-[tert-butyldimethylsilyloxy]-4,4,6,8,12-pentamethyl-5-oxo-12-tridecenoate Epothilone D