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L-缬氨醇

L-缬氨醇

CAS号：2026-48-4

英文名：(S)-(+)-2-Amino-3-methyl-1-butanol

分子式

C5H13NO

熔点

30-34°C

密度

0.926g/mLat 25°C(lit.)

分子量

103.163

沸点

81°C8mm Hg(lit.)

溶解度

信号词

危险品标志

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化合物简介

Valinol is an organic compound named after, and commonly produced from, the amino acid valine. The compound is chiral and is produced almost exclusively as the S‑isomer (also designated as the L‑isomer), due to the abundant supply of S-valine. It is part of a broader class of amino alcohols

基本信息

中文名称

L-缬氨醇

英文名称

(S)-(+)-2-Amino-3-methyl-1-butanol

中文别名

L-(+)-缬氨霉素、(S)-2-氨基-3-甲基-1-丁醇、L-(+)-缬氨醇、(S)-(+)-2-氨基-3-甲基-1-丁醇

英文别名

L-Val-ol、H-L-VAL-OL、Valinol、H-VALINOL、L-Valino、L-Valanol、H-VAL-OL、S-VALINOL、(S)-2-Amino-3-Methyl-1-Butanol、L-VALINAL、L-(+)-Valinol

CAS号

2026-48-4

分子式

C5H13NO

分子量

103.163

精确质量

103.1

PSA

46.25

LOGP

0.6623

编号系统

MDL号

MFCD00064296

BRN号

1719137

PubChem号

24890042

EINECS号

217-975-5

物化性质

外观与性状

白色至淡黄色晶体粉末

密度

0.926g/mLat 25°C(lit.)

沸点

81°C8mm Hg(lit.)

熔点

30-34°C

闪点

196°F

折射率

n20/D 1.4548(lit.)

稳定性

Stable under normal temperatures and pressures. Absorbs carbon dioxide from the air.

储存条件

2-8ºC

蒸汽压

0.182mmHg at 25°C

安全信息

安全说明

S26-S24/25

WGK Germany

3

危险类别码

R36

海关编码

29221980

危险品标志

Xi

生产方法及用途

用途

用作医药中间体，也可用于其他有机合成。用于有机合成，应用实例如下图所示：

合成路线

共找到76条合成路线 >

L-缬氨酸

L-缬氨醇

海关数据

共找到8个国家海关数据 >

国家/地区名称	海关编码	更新时间	操作
中国	2922199090	2019-03	查看
美国	2922199590	2019-03	查看
印度	29221990	2019-03	查看
欧盟	29221985	2019-03	查看
英国	2922198590	2019-03	查看
日本	292219019	2019-03	查看
韩国	2922199000	2019-03	查看
加拿大	2922190059	2019-03	查看

上游原料

共找到31个上游原料 >

5-(methylethyl)-3R-phenyl-3,6-dihydro-[1,4]oxazin-2-one

5-(methylethyl)-3R-phenyl-3,6-dihydro-[1,4]oxazin-2-one

L-缬氨酸盐酸盐

L-缬氨酸盐酸盐

2-bromo-3-methylbutan-1-ol

2-bromo-3-methylbutan-1-ol

(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

N-Benzoyl-Gly-Val-OEt

N-Benzoyl-Gly-Val-OEt

1-溴-3-甲基-2-丁酮

1-溴-3-甲基-2-丁酮

下游产品

共找到49个下游商品 >

(4S)-(-)-4-异丙基-1,3-恶唑烷-2-硫酮

(4S)-(-)-4-异丙基-1,3-恶唑烷-2-硫酮

(4S)-2-phenyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

(4S)-2-phenyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

(S)-N-(1-hydroxy-3-methylbutan-2-yl)-4-methylbenzenesulfonamide

(S)-N-(1-hydroxy-3-methylbutan-2-yl)-4-methylbenzenesulfonamide

(E)-(S)-(-)-N-(2-hydroxy-1-isopropylethyl)p-methoxyphenylmethylideneamine

(E)-(S)-(-)-N-(2-hydroxy-1-isopropylethyl)p-methoxyphenylmethylideneamine

(4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

(4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

Fmoc-L-beta-高缬氨酸

Fmoc-L-beta-高缬氨酸

上游原料

5-(methylethyl)-3R-phenyl-3,6-dihydro-[1,4]oxazin-2-one L-缬氨酸盐酸盐 2-bromo-3-methylbutan-1-ol (-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester N-Benzoyl-Gly-Val-OEt 1-溴-3-甲基-2-丁酮 (2S)-2-(benzylamino)-3-methylbutan-1-ol (S)-2-ethoxy-4,5-dihydro-4-(1-methylethyl)oxazole L-缬氨酸乙酯盐酸盐 (1S,1'R)-N-(2'-methoxy-1'-phenylethyl)-1-acetoxymethyl-2-methylpropylamine L-缬氨酸 (S)-2-((R)-1-(3,4-dimethoxybenzyl)-3,4-dihydroisoquinolin-2(1H)-yl)-4-isopropyl-4,5-dihydrooxazole (S)-2-((R)-1-butyl-3,4-dihydroisoquinolin-2(1H)-yl)-4-isopropyl-4,5-dihydrooxazole (S)-4-isopropyl-2-((R)-1-(2-methoxybenzyl)-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dihydrooxazole (1S,1'S)-(+)-N-(2'-hydroxy-1'-isopropylethyl)-1,2-diphenylethylamine L-Prolyl-leucyl-α-aminoisobutyryl-α-aminoisobutyryl-α-glutamyl-valinol (S)-2-(3,4-dihydroisoquinolin-2(1H)-yl)-4-isopropyl-4,5-dihydrooxazole L-缬氨酸甲酯盐酸盐 L-Pro-L-Leu-Aib-D-Iva-L-Glu-L-Vol 乙基缬氨酸酯 (S)-4-isopropyl-2-((R)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dihydrooxazole Cbz-L-缬氨醇 2-溴代异戊酸乙酯 2-溴-3-甲基丁酸乙醚 L-缬氨酸甲酯 (S)-4-isopropyl-2-((R)-1-propyl-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dihydrooxazole (4S,Z)-2-ethylidene-4-(1-methylethyl)-3-(2-propenyl)oxazolidine (S)-4-异丙基-2-恶唑烷酮 (S)-2-((R)-1-benzyl-3,4-dihydroisoquinolin-2(1H)-yl)-4-isopropyl-4,5-dihydrooxazole (5S)-5-isopropyl-3-phenyl-5,6-dihydro-2H-1,4-oxazine-2-one

下游产品

(4S)-(-)-4-异丙基-1,3-恶唑烷-2-硫酮 (4S)-2-phenyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole (S)-N-(1-hydroxy-3-methylbutan-2-yl)-4-methylbenzenesulfonamide (E)-(S)-(-)-N-(2-hydroxy-1-isopropylethyl)p-methoxyphenylmethylideneamine (4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole Fmoc-L-beta-高缬氨酸 (S)-4-(1-异丙基)-3-(1-氧代丁基)-2-恶唑烷酮 (S)-(-)-2-[2-(二苯基膦)苯基]-4-异丙基-2-唑啉 (S)-4-异丙基噻唑烷-2-硫 (S)-2-(2-溴苯基)-4-异丙基-4,5-二氢噁唑 (3R-顺)-(-)-3-异丙基-7α-甲基四氢吡咯并-[2,1-b]噁唑-5(6H)-酮 4-正丁基苯胺 L-缬氨醇盐酸盐 S-4,5-二氢-2-(2-((S)-4,5-二氢-4-异丙基噁唑-2-基)丙-2-基)-4-异丙基噁唑 (R)-1-(4-异丙基-2-硫氧代噻唑啉-3-基)乙酮 N-[(2S)-3-甲基-1-氧代-1-[2-[[(3S)-1,1,1-三氟-4-甲基-2-氧代戊烷-3-基]氨基甲酰]吡咯烷-1-基]丁烷-2-基]氨基甲酸苯甲酯 (S)-(+)-4-异丙基-3-丙酰-2-恶唑烷酮双[(S)-4-异丙基-4,5-二氢噁唑-2-基]甲烷 CBZ-L-缬氨酸 N-Boc-L-缬氨醇 (4S)-3-benzyl-4-propan-2-yl-1,3-thiazolidine-2-thione (S,S)-2,6-双(4-异丙基-2-恶唑啉-2-基)吡啶 1-(4-甲氧苯基)丙烷-1-OL 5-isopropyl-2-(4-methoxyphenyl)-3-methyl-1H-pyrrole 3-甲基-1-丁烯 (S)-2-异丙氨基-3-甲基-1-丁醇 N-苄氧羰基-D-缬氨酸叔丁氧羰基-β-亮氨酸 5-propan-2-ylmorpholin-3-one N,N-二苄基-L-缬氨醇 (2S)-2-异丙基-1-(甲基磺酰基)氮丙啶 (S)-3-异丙基吗啉 1-[(2S)-1-methoxy-3-methylbutan-2-yl]-1H-imidazole (S)-3-Methyl-2-(2-methyl-imidazol-1-yl)-butan-1-ol (4S,4′S)-(-)-2,2′-(3-戊烯基)双(4-异丙基噁唑啉) Fmoc-缬氨醇 (3S)-3-ISOPROPYL BICYCLIC LACTAM (S)-4-异丙基-2-恶唑烷酮 2-phenyl-5-propan-2-yl-1H-pyrrole 2-甲基咪唑