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(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

CAS号：202719-31-1

英文名：(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

分子式

C31H46N4O11Si

熔点

密度

分子量

678.803

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

英文名称

(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

中文别名

英文别名

CAS号

202719-31-1

分子式

C31H46N4O11Si

分子量

678.803

精确质量

678.293

PSA

190.15

LOGP

1.3439

合成路线

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1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

(2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate

上游原料

共找到6个上游原料 >

1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

{(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetaldehyde

{(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetaldehyde

(E)-3'-O-Acetyl-5'-(3-{(3'R)-5'-O-(tert-butyldimethylsilyl)-3-[(2-trimethylsilylethoxy)methyl]-3'-deoxythymidin-3'-yl}-2-oxopropylidene)-5'-deoxythymidine

(E)-3'-O-Acetyl-5'-(3-{(3'R)-5'-O-(tert-butyldimethylsilyl)-3-[(2-trimethylsilylethoxy)methyl]-3'-deoxythymidin-3'-yl}-2-oxopropylidene)-5'-deoxythymidine

1-{(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-[2-oxo-3-(triphenyl-λ5-phosphanylidene)-propyl]-tetrahydro-furan-2-yl}-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

1-{(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-[2-oxo-3-(triphenyl-λ5-phosphanylidene)-propyl]-tetrahydro-furan-2-yl}-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

1-[(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-imidazol-1-yl-2-oxo-ethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

1-[(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-imidazol-1-yl-2-oxo-ethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

{(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetic acid

{(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetic acid

下游产品

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Acetic acid (2R,3S,5R)-2-{4-[(2S,3R,5R)-2-formyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-3-oxo-butyl}-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

Acetic acid (2R,3S,5R)-2-{4-[(2S,3R,5R)-2-formyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-3-oxo-butyl}-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-deoxythymidine

5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-deoxythymidine

5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine

5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine

3'-O-Acetyl-5'-{3-[(3'R)-5'-(4,4'-dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine

3'-O-Acetyl-5'-{3-[(3'R)-5'-(4,4'-dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine

2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

上游原料

1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione {(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetaldehyde (E)-3'-O-Acetyl-5'-(3-{(3'R)-5'-O-(tert-butyldimethylsilyl)-3-[(2-trimethylsilylethoxy)methyl]-3'-deoxythymidin-3'-yl}-2-oxopropylidene)-5'-deoxythymidine 1-{(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-[2-oxo-3-(triphenyl-λ5-phosphanylidene)-propyl]-tetrahydro-furan-2-yl}-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 1-[(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-imidazol-1-yl-2-oxo-ethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione {(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetic acid

下游产品

Acetic acid (2R,3S,5R)-2-{4-[(2S,3R,5R)-2-formyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-3-oxo-butyl}-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-deoxythymidine 5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine 3'-O-Acetyl-5'-{3-[(3'R)-5'-(4,4'-dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine 2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate