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2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

CAS号：202719-43-5

英文名：2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

分子式

C38H48N7O17P

熔点

密度

分子量

905.798

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

英文名称

2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

中文别名

英文别名

CAS号

202719-43-5

分子式

C38H48N7O17P

分子量

905.798

精确质量

905.284

PSA

334.23

LOGP

0.14448

合成路线

202719-22-0

1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

202719-43-5

2-Cyanoethyl {5'-[3-((3'R)-3'-deoxythymidin-3'-yl)-2-oxopropyl]-5'-deoxythymidin-3'-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

上游原料

共找到18个上游原料 >

202719-38-8

(E)-3'-O-Acetyl-5'-{3-[(3'R)-3-benzyloxymethyl-5'-O-(tert-butyldimethylsilyl)-3'-deoxythymidin-3'-yl]-2-oxopropylidene}-5'-deoxythymidine

202719-28-6

1-{(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-[2-oxo-3-(triphenyl-λ5-phosphanylidene)-propyl]-tetrahydro-furan-2-yl}-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

155193-99-0

5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-deoxythymidine

104495-24-1

2-Cyanoethyl (3'-O-acetylthymidin-5'-O-yl)[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-O-yl]phosphinate

202719-22-0

1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione

202719-42-4

2-Cyanoethyl {5'-[(E)-3-((3'R)-3-benzyloxymethyl-5'-O-tert-butyldimethylsilyl-3'-deoxythymidin-3'-yl)-2-oxopropylidene]-5'-deoxythymidin-3'-O-yl}(3'-acetylthymidin-5'-O-yl)phosphinate

上游原料

(E)-3'-O-Acetyl-5'-{3-[(3'R)-3-benzyloxymethyl-5'-O-(tert-butyldimethylsilyl)-3'-deoxythymidin-3'-yl]-2-oxopropylidene}-5'-deoxythymidine 1-{(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-[2-oxo-3-(triphenyl-λ5-phosphanylidene)-propyl]-tetrahydro-furan-2-yl}-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-deoxythymidine 2-Cyanoethyl (3'-O-acetylthymidin-5'-O-yl)[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-O-yl]phosphinate 1-[(2R,4S,5S)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 2-Cyanoethyl {5'-[(E)-3-((3'R)-3-benzyloxymethyl-5'-O-tert-butyldimethylsilyl-3'-deoxythymidin-3'-yl)-2-oxopropylidene]-5'-deoxythymidin-3'-O-yl}(3'-acetylthymidin-5'-O-yl)phosphinate Acetic acid (2R,3S,5R)-2-{(2-cyano-ethoxy)-[(2S,3S,5R)-2-formyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-phosphoryloxymethyl}-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester P-(2-cyano-ethyl)-thymidylyl-(3'->5')-O3'-acetyl-thymidine (2R,3S,5R)-2-(4-((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-3-oxobutyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl acetate {(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetaldehyde (3'-O-Acetylthymidin-5'-O-yl)(2-cyanoethoxy)[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-O-yl]phosphane (E)-3'-O-Acetyl-5'-(3-{(3'R)-5'-O-(tert-butyldimethylsilyl)-3-[(2-trimethylsilylethoxy)methyl]-3'-deoxythymidin-3'-yl}-2-oxopropylidene)-5'-deoxythymidine 1-[(2R,4R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-imidazol-1-yl-2-oxo-ethyl)-tetrahydro-furan-2-yl]-5-methyl-3-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 5'-{3-[(3'R)-5'-(4,4'-Dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine 3'-O-Acetyl-5'-{3-[(3'R)-5'-(4,4'-dimethoxytrityl)-3'-deoxythymidin-3'-yl]-2-oxopropyl}-5'-deoxythymidine {(2S,3R,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-[5-methyl-2,4-dioxo-3-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl}-acetic acid