化合物简介
A novel brain-selective MAO inhibitor, Ladostigil can selectively reverse the behavioral and neurochemical effects induced by prenatal stress without affecting the behavior of controls. Antidepressant .
基本信息
中文名称
乙基甲基-氨基甲酸 (3R)-2,3-二氢-3-(2-丙炔氨基)-1H-茚-5-基酯酒石酸盐
英文名称
(2R,3R)-2,3-dihydroxybutanedioic acid,[(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate
中文别名
英文别名
UNII-2J1346C51H、Ladostigil Tartrate、ethylmethylcarbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutanedioate、R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N\'-propargyl-1-aminoindan tartrate、R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N\'-propargyl-1-aminoindan L-tartrate、(3R)-3-(prop-2-ynylamino)-2,3,-dihydro-1H-indan-5-yl ethyl methyl carbamate tartrate、TV-3219、[(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate、(2R,3R)-2,3-dihydroxybutanedioic acid、ethyl-methyl-carbamic acid (R)-3-prop-2-ynylamino-indan-5-yl ester tartrate、TV-3326
CAS号
209394-46-7
分子式
C36H46N4O10
分子量
694.771
精确质量
694.321
PSA
198.2
LOGP
3.3536
编号系统
UNII
2J1346C51H
物化性质
沸点
412.4ºC at 760 mmHg
闪点
203.2ºC
蒸汽压
5.19E-07mmHg at 25°C
合成路线
