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文多灵

文多灵

CAS号：2182-14-1

英文名：Vindoline

分子式

C25H32N2O6

熔点

163-165ºC

密度

1.33 g/cm3

分子量

456.531

沸点

569.8ºC at 760 mmHg

溶解度

信号词

Warning

危险品标志

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化合物简介

Vindoline is a chemical precursor to vinblastine.

基本信息

中文名称

文多灵

英文名称

Vindoline

中文别名

文朵灵

英文别名

4-acetoxy-3-hydroxy-16-methoxy-1-methyl-6,7-didehydro-aspidospermidine-3-carboxylic acid methyl ester、vindolin

CAS号

2182-14-1

分子式

C25H32N2O6

分子量

456.531

精确质量

456.226

PSA

88.54

LOGP

1.6442

编号系统

EINECS号

218-558-0

物化性质

外观与性状

白色或灰白色固体

密度

1.33 g/cm3

沸点

569.8ºC at 760 mmHg

熔点

163-165ºC

闪点

298.4ºC

折射率

1.626

储存条件

-20ºC Freezer

蒸汽压

0mmHg at 25°C

安全信息

危险性防范说明

P281

危险性描述

H341

信号词

Warning

危险标志

GHS08

合成路线

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methyl (2S,3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-2,5-dihydroxy-8-methoxy-6-methyl-2,3,3a,3a1,4,5,5a,6,11,12-decahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate

methyl (2S,3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-2,5-dihydroxy-8-methoxy-6-methyl-2,3,3a,3a1,4,5,5a,6,11,12-decahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate

文多灵

上游原料

共找到41个上游原料 >

6-甲氧基-1-甲基-1H-吲哚-3-甲醛

6-甲氧基-1-甲基-1H-吲哚-3-甲醛

methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-3a-ethyl-4-hydroxy-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-3a-ethyl-4-hydroxy-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-thioxo-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-thioxo-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-acetoxy-3a-ethyl-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-acetoxy-3a-ethyl-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

5-{{4-[1-Benzyloxy-meth-(E)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester

5-{{4-[1-Benzyloxy-meth-(E)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester

methyl (3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-oxo-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

methyl (3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-oxo-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate

下游产品

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脱乙酰基文多灵

脱乙酰基文多灵

tert-butyl (2S)-2-[(1R,2S)-1-methoxy-2-methylbut-3-enyl]pyrrolidine-1-carboxylate

tert-butyl (2S)-2-[(1R,2S)-1-methoxy-2-methylbut-3-enyl]pyrrolidine-1-carboxylate

长春素

脱水长春碱

脱水长春碱

上游原料

6-甲氧基-1-甲基-1H-吲哚-3-甲醛 methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-3a-ethyl-4-hydroxy-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-thioxo-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-acetoxy-3a-ethyl-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate 5-{{4-[1-Benzyloxy-meth-(E)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester methyl (3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-oxo-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate methyl (2S,3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-6-methyl-2-((triisopropylsilyl)oxy)-2,3,3a,3a1,4,5,5a,6,11,12-decahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate methyl (2S,3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-2,5-dihydroxy-8-methoxy-6-methyl-2,3,3a,3a1,4,5,5a,6,11,12-decahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate methyl (2S,3aS,3a1R,4R,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-oxo-2-((triisopropylsilyl)oxy)-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate methyl (3aS,3a1R,4S,5S,5aR,10bS)-4-(benzyloxy)-3a-ethyl-8-methoxy-6-methyl-1-oxo-2,3,3a,4,5a,6,11,12-octahydro-3a1,5-epoxyindolizino[8,1-cd]carbazole-5(1H)-carboxylate 11-羟基他波宁 N1-methyl-6-methoxytryptamine 4-iodo-3-nitrophenyl methanesulfonate tert-butyl 3-(2-acetoxyethyl)-2-iodo-6-((methylsulfonyl)oxy)-1H-indole-1-carboxylate methyl 2-(3-(2-((N-(((2S)-4-ethyl-5-hydroxytetrahydrofuran-2-yl)methyl)-2,4-dinitrophenyl)sulfonamido)ethyl)-6-((methylsulfonyl)oxy)-1H-indol-2-yl)acrylate 对硝基苯基甲烷磺酸酯 (E)-3-nitro-4-(3-oxoprop-1-en-1-yl)phenyl methanesulfonate 脱乙酰基文多灵 4'-甲基磺酰乙酰苯胺 (E)-3-(4-((methylsulfonyl)oxy)-2-nitrophenyl)allyl acetate (6E)-8-hydroxy-3,7-dimethylocta-2,6-dienal-1-t (E)-3-(2-formamido-4-((methylsulfonyl)oxy)phenyl)allyl acetate 4-acetamido-3-nitrophenyl methanesulfonate 乙酸酐 4-氨基苯酚甲磺酸酯 (E)-3-(2-isocyano-4-((methylsulfonyl)oxy)phenyl)allyl acetate N-(2-(6-methoxy-1-methyl-1H-indol-3-yl)ethyl)hydrazinecarboxamide 5-[2-(6-Methoxy-1-methyl-1H-indol-3-yl)-ethylamino]-[1,3,4]oxadiazole-2-carboxylic acid methyl ester Methanesulfonic acid 4-amino-3-nitro-phenyl ester (-)-17β-Hydroxy-11-methoxytabersonine methyl 2-(2-((2-(6-methoxy-1-methyl-1H-indol-3-yl)ethyl)carbamoyl)hydrazineyl)-2-oxoacetate N-(2-(6-methoxy-1-methyl-1H-indol-3-yl)ethyl)-1H-imidazole-1-carboxamide methyl (Z)-5-(4-((benzyloxy)methylene)-N-(2-(6-methoxy-1-methyl-1H-indol-3-yl)ethyl)hexanamido)-1,3,4-oxadiazole-2-carboxylate (5R,7S,12R,19S)-2,3-didehydro-7-hydroxy-16-[(methanesulfonyl)oxy]aspidospermidine-3-carboxylic acid methyl ester (3aR,5S,5aR,10bR,12bR)-3a-Ethyl-5-hydroxy-8-methoxy-6-methyl-4-oxo-3a,4,5,5a,6,11,12,12b-octahydro-1H-6,12a-diaza-indeno[7,1-cd]fluorene-5-carboxylic acid methyl ester (-)-11-Mesyloxytabersonine 6-methoxy-1-methylindole 3-(2-hydroxyethyl)-6-methanesulfonyloxy-2-(1-methoxycarbonylvinyl)indole-1-carboxylic acid tert-butyl ester 1-[tert-butoxycarbonyl]-3-[2-[[(2,4-dinitrophenyl)sulfonyl][[(2S)-4-ethyl-2,3-dihydro-2-furanyl]methyl]amino]ethyl]-α-methylene-6-[(methanesulfonyl)oxy]-1H-indole-2-acetic acid methyl ester methyl 2-(3-(2-((((2S)-4-ethyl-5-hydroxytetrahydrofuran-2-yl)methyl)amino)ethyl)-6-((methylsulfonyl)oxy)-1H-indol-2-yl)acrylate

下游产品

脱乙酰基文多灵 tert-butyl (2S)-2-[(1R,2S)-1-methoxy-2-methylbut-3-enyl]pyrrolidine-1-carboxylate 长春素脱水长春碱