化合物简介
Lumiracoxib (rINN) is a carboxylic acid COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige (sometimes misquoted as \"Prestige\" by the media).
基本信息
中文名称
罗美昔布
英文名称
lumiracoxib
中文别名
2-[(2-氯-6-氟苯基)氨基」-5-甲基苯乙酸、鲁米昔布
英文别名
[14C]-Lumiracoxib、2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid、Prexige、Joicela、Prexige (Novartis)、5-methyl-2-(2\'-chloro-6\'-fluoroanilino)phenylacetic acid、Lumiracoxib、2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid、(2-((2-chloro-6-fluorophenyl)-amino)-5-methylphenyl)-acetic acid、2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid、Lumiracoxib [USAN:INN]、COX189
CAS号
220991-20-8
分子式
C15H13ClFNO2
分子量
293.721
精确质量
293.062
PSA
49.33
LOGP
4.2312
编号系统
UNII
V91T9204HU
物化性质
外观与性状
淡黄色固体
密度
1.363 g/cm3
沸点
395.7ºC at 760 mmHg
熔点
139-141ºC
闪点
193.1ºC
折射率
1.628
蒸汽压
5.68E-07mmHg at 25°C
