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柔红霉素盐酸盐

柔红霉素盐酸盐

CAS号：23541-50-6

英文名：Daunorubicin hydrochloride(BICINS)

分子式

C27H30ClNO10

熔点

188 - 190ºC

密度

分子量

563.981

沸点

770ºC at 760 mmHg

溶解度

信号词

Danger

危险品标志

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化合物简介

Anthracycline antibiotic related to the rhodomycins. Antineoplastic.

基本信息

中文名称

柔红霉素盐酸盐

英文名称

Daunorubicin hydrochloride(BICINS)

中文别名

盐酸柔红霉素、柔红霉素盐酸盐、道诺霉素盐酸盐、盐酸佐柔比星、红比霉素盐酸盐

英文别名

DAUNOBLASTINE、DAUNORUBICIN HCL、Daunorubicin HCl、Hydroxydaunorubicin Hydrochloride、DAUNOMYCINE HCL、ndc0082-4155、Dau hydrochloride、Daunorubicin (Hydrochloride)、Daunorubicinol hydrochloride、ondena、DAUNOMYCIN HCL、Daunomycin hydrochloride、daunoblastin、daunoblastina、Daunorubicin Hydrochloride、WP900 HYDROCHLORIDE、Cerubidine

CAS号

23541-50-6

分子式

C27H30ClNO10

分子量

563.981

精确质量

563.156

PSA

185.84

LOGP

2.5312

编号系统

MDL号

MFCD00076118

EINECS号

245-723-4

PubChem号

24894229

BRN号

4229221

RTECS号

HB7878000

物化性质

外观与性状

橙色-红色粉末

沸点

770ºC at 760 mmHg

熔点

188 - 190ºC

闪点

419.5ºC

稳定性

Stability

储存条件

-20ºC

蒸汽压

6.99E-26mmHg at 25°C

安全信息

安全说明

S22-S36/37-S45

危险类别码

R22; R40; R42/43

海关编码

2932999099

危险品运输编码

UN 2811

危险类别

6.1(b)

包装等级

III

危险品标志

Xn

危险标志

GHS06, GHS08

危险性描述

H301; H334; H351

危险性防范说明

P261; P281; P301 + P310; P342 + P311

信号词

Danger

合成路线

共找到19条合成路线 >

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)isonicotinohydrazide hydrochloride

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)isonicotinohydrazide hydrochloride

异烟肼

柔红霉素盐酸盐

柔红霉素盐酸盐

上游原料

共找到8个上游原料 >

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)nicotinohydrazide hydrochloride

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)nicotinohydrazide hydrochloride

4-amino-N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)benzohydrazide hydrochloride

4-amino-N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)benzohydrazide hydrochloride

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)isonicotinohydrazide hydrochloride

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)isonicotinohydrazide hydrochloride

ethyl 4-(2-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)hydrazine-1-carbonyl)benzoate hydrochloride

ethyl 4-(2-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)hydrazine-1-carbonyl)benzoate hydrochloride

ethyl 3-(2-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)hydrazine-1-carbonyl)benzoate hydrochloride

ethyl 3-(2-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)hydrazine-1-carbonyl)benzoate hydrochloride

daunoform

下游产品

共找到19个下游商品 >

柔红酮

5,12-Naphthacenedione, 8-acetyl-10-[[3-[(2-amino-4-methyl-1-oxopentyl)amino]-2,3,6-trideoxy-.α.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, [8S-[8.α.,10.α.(R*)]]-

5,12-Naphthacenedione, 8-acetyl-10-[[3-[(2-amino-4-methyl-1-oxopentyl)amino]-2,3,6-trideoxy-.α.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, [8S-[8.α.,10.α.(R*)]]-

9-乙酰基-6,9,11-三羟基-10-[5-羟基-4-(4-甲氧基哌啶-1-基)-6-甲基四氢吡喃-2-基]氧基-1-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮

9-乙酰基-6,9,11-三羟基-10-[5-羟基-4-(4-甲氧基哌啶-1-基)-6-甲基四氢吡喃-2-基]氧基-1-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮

盐酸依达比星

盐酸依达比星

(8S,10S)-6,8,11-trihydroxy-10-(((2R,4S,5S,6S)-5-hydroxy-4-(4-methoxypiperidin-1-yl)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(1-hydroxyethyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

(8S,10S)-6,8,11-trihydroxy-10-(((2R,4S,5S,6S)-5-hydroxy-4-(4-methoxypiperidin-1-yl)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(1-hydroxyethyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

[2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] acetate,hydrochloride

[2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] acetate,hydrochloride

上游原料

N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)nicotinohydrazide hydrochloride 4-amino-N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)benzohydrazide hydrochloride N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)isonicotinohydrazide hydrochloride ethyl 4-(2-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)hydrazine-1-carbonyl)benzoate hydrochloride ethyl 3-(2-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)hydrazine-1-carbonyl)benzoate hydrochloride daunoform 盐酸佐柔比星 Benzoic acid, 4-hydroxy-, [1-[4-[(3-amino-2,3,6-trideoxy-.α.-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide, monohydrochloride, (2S-cis)-

下游产品

柔红酮 5,12-Naphthacenedione, 8-acetyl-10-[[3-[(2-amino-4-methyl-1-oxopentyl)amino]-2,3,6-trideoxy-.α.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, [8S-[8.α.,10.α.(R*)]]- 9-乙酰基-6,9,11-三羟基-10-[5-羟基-4-(4-甲氧基哌啶-1-基)-6-甲基四氢吡喃-2-基]氧基-1-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮盐酸依达比星 (8S,10S)-6,8,11-trihydroxy-10-(((2R,4S,5S,6S)-5-hydroxy-4-(4-methoxypiperidin-1-yl)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(1-hydroxyethyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione [2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] acetate,hydrochloride L-Daunosamine hydrochloride (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy)-6a,7,8,9,10,10a-hexahydro-5,8,12-trihydroxy-1-methoxy-6,11-naphthacenedione 盐酸多柔比星 (8R)-8-乙酰基-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌 (8S,10S)-10-[(3-氨基-2,3,6-三脱氧-alpha-L-吡喃来苏己糖基)氧基]-8-(2-溴-1,1-二甲氧基乙基)-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌伊达比星 3-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-(3-氰基-4-吗啉基)-2,3,6-三脱氧吡喃己糖苷溴二去氢多柔比星酮洋红霉素酮 6,9,11-三羟基-9-(1-羟基乙基)-7-[(4S,5S,6S)-5-羟基-6-甲基-4-吗啉-4-基四氢吡喃-2-基]氧基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮道诺霉素 3'-(4-吗啉基)-3'-去氨基柔红霉素