百科

霉酚酸

霉酚酸

CAS号：24280-93-1

英文名：mycophenolic acid

分子式

C17H20O6

熔点

141°C

密度

1.29 g/cm3

分子量

320.337

沸点

611.6ºC at 760 mmHg

溶解度

信号词

Danger

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.

基本信息

中文名称

霉酚酸

英文名称

mycophenolic acid

中文别名

麦考酚酸、E-4-甲基-6-(1,3-二氢-7-甲基-4-羟基-6-甲氧基-3-氧代-5-异苯并呋喃基)-4-己烯酸、(E)-6-(1,3-二氢-4-羟基-6-甲氧基-7-甲基-3-氧代-5-异苯并呋喃基)-4-甲基l-4-己烯酸

英文别名

4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-、Mycophenolinsure、mycophenolate、Mycophenolic acid、melbex、micofenolicoacido、Micophenolic acid、6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid、Mycophenolic

CAS号

24280-93-1

分子式

C17H20O6

分子量

320.337

精确质量

320.126

PSA

93.06

LOGP

2.7332

编号系统

MDL号

MFCD00036814

EINECS号

246-119-3

BRN号

1295848

PubChem号

24896987

物化性质

外观与性状

白色至灰白色粉末

密度

1.29 g/cm3

沸点

611.6ºC at 760 mmHg

熔点

141°C

闪点

225.8ºC

稳定性

Stable at normal temperatures and pressures.

储存条件

2-8ºC

蒸汽压

8.18E-16mmHg at 25°C

安全信息

RTECS号

MP8050000

安全说明

S53-S45

WGK Germany

3

危险类别码

R22

危险品运输编码

2811

海关编码

2932209090

危险类别

6.1(b)

包装等级

III

危险品标志

Xn

危险性防范说明

P201; P273; P281; P308 + P313; P501

危险性描述

H302; H341; H360D; H372; H410

危险标志

GHS07, GHS08, GHS09

信号词

Danger

生产方法及用途

用途

免疫抑制剂中间体。

合成路线

共找到12条合成路线 >

7-hydroxy-6-[(E)-6-hydroxy-3-methylhex-2-enyl]-5-methoxy-4-methyl-3H-2-benzofuran-1-one

7-hydroxy-6-[(E)-6-hydroxy-3-methylhex-2-enyl]-5-methoxy-4-methyl-3H-2-benzofuran-1-one

霉酚酸

海关数据

共找到8个国家海关数据 >

国家/地区名称	海关编码	更新时间	操作
中国	2932209090	2019-03	查看
美国	2932204500	2019-03	查看
印度	29322090	2019-03	查看
欧盟	29322090	2019-03	查看
英国	2932209090	2019-03	查看
日本	293220090	2019-03	查看
韩国	2932299000	2019-03	查看
加拿大	2932200000	2019-03	查看

上游原料

共找到33个上游原料 >

(E)-6-(1,3-二氢-4,6-二甲氧基-7-甲基-3-氧代-5-异苯并呋喃基)-4-甲基-4-己烯酸

(E)-6-(1,3-二氢-4,6-二甲氧基-7-甲基-3-氧代-5-异苯并呋喃基)-4-甲基-4-己烯酸

6-((E)-3,7-Dimethyl-octa-2,6-dienyl)-5,7-dimethoxy-4-methyl-3H-isobenzofuran-1-one

6-((E)-3,7-Dimethyl-octa-2,6-dienyl)-5,7-dimethoxy-4-methyl-3H-isobenzofuran-1-one

[6-methoxy-4-(2-methoxyethoxymethoxy)-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl]-acetaldehyde

[6-methoxy-4-(2-methoxyethoxymethoxy)-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl]-acetaldehyde

(E)-1-acetoxy-6-(tert-butyldimethylsiloxy)-3-methyl-2-hexene

(E)-1-acetoxy-6-(tert-butyldimethylsiloxy)-3-methyl-2-hexene

(E)-2-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-3-methoxy-5-(methoxymethoxymethyl)-4-methylphenol

(E)-2-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-3-methoxy-5-(methoxymethoxymethyl)-4-methylphenol

(E)-3-methyl-6-[(tert-butyldimethylsilyl)oxy]-2-hexen-1-ol

(E)-3-methyl-6-[(tert-butyldimethylsilyl)oxy]-2-hexen-1-ol

下游产品

共找到11个下游商品 >

7-hydroxy-5-methoxy-4-methyl-6-[2-(2-methyl-5-oxooxolan-2-yl)ethyl]-3H-2-benzofuran-1-one

7-hydroxy-5-methoxy-4-methyl-6-[2-(2-methyl-5-oxooxolan-2-yl)ethyl]-3H-2-benzofuran-1-one

6-O-甲基霉酚酸甲酯

6-O-甲基霉酚酸甲酯

O-去甲基霉酚酸

O-去甲基霉酚酸

甲基6’-去甲基-4’-对甲苯磺酰基麦考酚酯

甲基6’-去甲基-4’-对甲苯磺酰基麦考酚酯

霉酚酸甲酯

霉酚酸甲酯

霉酚酸酯

上游原料

(E)-6-(1,3-二氢-4,6-二甲氧基-7-甲基-3-氧代-5-异苯并呋喃基)-4-甲基-4-己烯酸 6-((E)-3,7-Dimethyl-octa-2,6-dienyl)-5,7-dimethoxy-4-methyl-3H-isobenzofuran-1-one [6-methoxy-4-(2-methoxyethoxymethoxy)-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl]-acetaldehyde (E)-1-acetoxy-6-(tert-butyldimethylsiloxy)-3-methyl-2-hexene (E)-2-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-3-methoxy-5-(methoxymethoxymethyl)-4-methylphenol (E)-3-methyl-6-[(tert-butyldimethylsilyl)oxy]-2-hexen-1-ol (E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol (E)-6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enal (E)-6-acetoxy-4-methyl-4-hexenal (E)-8-(tert-butyldimethylsiloxy)-1-methoxy-5-methyl-4-octen-1-yne (E)-3-(6-((tert-butyldimethylsilyl)oxy)-3-methylhex-2-en-1-yl)-2-hydroxy-4-methoxy-6-((methoxymethoxy)methyl)-5-methylbenzoic acid 2,4-dimethoxy-5-methyl-2,3-dihydrobenzo[1,2-b:5,6-c']difuran-8(6H)-one 7-hydroxy-5-methoxy-4-methylphthalide 3-((E)-3,7-Dimethyl-octa-2,6-dienyl)-6-(2,2-dimethyl-propionyloxymethyl)-5-hydroxymethyl-2,4-dimethoxy-benzoic acid methyl ester (4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)acetaldehyde 葡萄糖 2-(4-tert-butyldimethylsilyloxy-1,3-dihydro-6-methoxy-7-methyl-3-oxoisobenzofuran-5-yl)acetaldehyde 6-O-甲基霉酚酸甲酯 1,3-dihydro-4-hydroxy-5-iodo-6-methoxy-7-methyl-3-oxo-5-isobenzofuran methyl (E)-6-(6-methoxy-7-methyl-3-oxo-4-((2-(trimethylsilyl)ethoxy)methoxy)-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate (E)-6-(5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-en-1-yl)-5,7-dimethoxy-4-methylisobenzofuran-1(3H)-one 4-hydroxy-2-methoxy-5-methyl-2,3-dihydrobenzo[1,2-b:5,6-c']difuran-8(6H)-one 6-Iodo-5-methoxy-4-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-3H-isobenzofuran-1-one 6-(2-hydroxy-3-methylbut-3-enyl)-5-methoxy-7-(2-methoxyethoxymethoxy)-4-methyl-3H-isobenzofuran-2-one (E)-methyl 3-(3,7-dimethylocta-2,6-dien-1-yl)-5-formyl-2,4-dimethoxy-6-((pivaloyloxy)methyl)benzoate RS-61443 霉酚酸甲酯 (E)-acetic acid 6-hydroxy-3-methylhex-2-enyl ester 7-hydroxy-6-[(E)-6-hydroxy-3-methylhex-2-enyl]-5-methoxy-4-methyl-3H-2-benzofuran-1-one (+/-)-4-[1,3-Dihydro-4-(tert-butyldimethylsilyloxy)-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-3-hydroxy-2-methylbutene methyl (E)-3-(3,7-dimethylocta-2,6-dien-1-yl)-5-formyl-2,4-dihydroxy-6-((pivaloyloxy)methyl)benzoate methyl (E)-3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4-dimethoxy-5-methyl-6-((pivaloyloxy)methyl)benzoate Ethyl E-6-<1,3-Dihydro-4-(tert-butyldimethylsilyloxy)-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl>-4-methyl-4-hexenoate

下游产品

7-hydroxy-5-methoxy-4-methyl-6-[2-(2-methyl-5-oxooxolan-2-yl)ethyl]-3H-2-benzofuran-1-one 6-O-甲基霉酚酸甲酯 O-去甲基霉酚酸甲基6’-去甲基-4’-对甲苯磺酰基麦考酚酯霉酚酸甲酯霉酚酸酯甲基4’-对甲苯磺酰基麦考酚酯 3-(5-methoxy-2,6-dimethyl-9-oxo-4,7-dihydro-3H-furo[3,4-h]chromen-2-yl)propanoic acid 4,5-二甲基间苯二酚 4’-去甲基-6’-对甲苯磺酰基霉酚酸 1,3-二氢-4-羟基-6-甲氧基-G,7-二甲基-3-氧代-5-异苯并呋喃己酸