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3’-脱氧-3-氟胸苷

3’-脱氧-3-氟胸苷

CAS号：25526-93-6

英文名：3,-Deoxy-3,-fluoro Thymidine

分子式

C10H13FN2O4

熔点

176-178ºC(lit.)

密度

1.44 g/cm3

分子量

244.22

沸点

溶解度

信号词

危险品标志

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化合物简介

An antiviral agent.

基本信息

中文名称

3’-脱氧-3-氟胸苷

英文名称

3,-Deoxy-3,-fluoro Thymidine

中文别名

阿洛夫定、3\'-脱氧-3\'-氟胸苷、3’-deoxy-3’-fluorothymidine、3\'-脱氧-3\'-氟化胸腺嘧啶脱氧核苷

英文别名

3\'-Deoxy-3\'-fluorothymidine

CAS号

25526-93-6

分子式

C10H13FN2O4

分子量

244.22

精确质量

244.086

PSA

84.32

LOGP

-0.5371

编号系统

PubChem号

24862180

MDL号

MFCD00056058

物化性质

外观与性状

无色固体

密度

1.44 g/cm3

熔点

176-178ºC(lit.)

折射率

1.565

合成路线

5'-O-三苯甲基-3'-O-甲磺酰基胸苷

5'-O-三苯甲基-3'-O-甲磺酰基胸苷

司他夫定

3’-脱氧-3-氟胸苷

3’-脱氧-3-氟胸苷

上游原料

共找到54个上游原料 >

(2R,3R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-methoxytetrahydrofuran-3-yl trifluoromethanesulfonate

(2R,3R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-methoxytetrahydrofuran-3-yl trifluoromethanesulfonate

((2S,3R)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl pivalate

((2S,3R)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl pivalate

Methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-arabinofuranoside

Methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-arabinofuranoside

methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-ribofuranoside

methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-ribofuranoside

methyl 5-O-benzyl-3-fluoro-3-deoxy-β-D-arabino-furanoside

methyl 5-O-benzyl-3-fluoro-3-deoxy-β-D-arabino-furanoside

[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl methanesulfonate

[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl methanesulfonate

上游原料

(2R,3R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-methoxytetrahydrofuran-3-yl trifluoromethanesulfonate ((2S,3R)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl pivalate Methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-arabinofuranoside methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-ribofuranoside methyl 5-O-benzyl-3-fluoro-3-deoxy-β-D-arabino-furanoside [(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl methanesulfonate methyl 2,3-dideoxy-3-fluoro-α-D-erythro-pentafuranoside methyl 5-O-benzyl-2-O-tosyl-3-fluoro-3-deoxy-β-D-arabino-furanoside Methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-α-D-arabinofuranoside methyl 5-O-tert-butyldiphenylsilyl-2,3-dideoxy-3-fluoro-α-D-erythro-pentafuranoside (2S，3R，4S，5R)-5-((苄氧基)甲基)-4-氟-2-甲氧基四氢呋喃-3-醇 3',5'-二-O-甲磺酰基胸苷 2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-β-D-THREO-PENTOFURANOSYL)-THYMINE ((2R,3R,4S,5R)-4-chloro-3-fluoro-5-methoxytetrahydrofuran-2-yl)methanol 2-Chloro-4-methoxy-5-methylpyrimidine 1-(2,3-二脱氧-3-氟-5-O-三苯甲基呋喃戊糖基)-5-甲基-2,4(1H,3H)-嘧啶二酮 1,5-Di-O-benzoyl-2,3-dideoxy-3-fluoro-β-D-erythro-pentofuranose 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-threo-pentofuranosyl)thymine methyl 5-O-benzyl-2-chloro-2,3-dideoxy-3-fluoro-β-D-ribofuranoside 1-((2R,4R,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮 5-O-(4,4-二甲氧基三苯甲游基)-2,3-脱水胸腺嘧啶脱氧核苷甲基2,3-二脱氧-3-氟-5-O-(4-苯基苯甲酰基)-α-D-赤型-呋喃戊糖苷 5’-O-三苯甲基胸苷 methyl 3-fluoro-α-D-3-deoxy-arabinofuranoside 1-(5-O-tert-butyldiphenylsilyl-2-deoxy-3-O-methylsulfonyl-α,β-D-erythro-pentofuranosyl)thymine methyl 2,5-di-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside 1,5-Di-O-benzoyl-2,3-dideoxy-3-fluoro-α-D-erythro-pentofuranose Benzoic acid (2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 2,3’-脱水胸苷 ((2R,3R,4S)-4-(benzoyloxy)-5-bromo-3-fluorotetrahydrofuran-2-yl)methyl benzoate 5’-三苯甲基-2’-脱氧-2,3’-双脱氢胸苷 methyl 3-deoxy-5-O-benzoyl-3-fluoro-2-O-tosyl-β-D-arabinofuranoside 1-(2-chloro-2,3-dideoxy-3-fluoro-β-D-ribofuranosyl)thymine Methyl 2-deoxy-5-O-(4-phenylbenzoyl)-β-D-threo-pentofuranoside [(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate ((2R,3R,4R)-4-(benzoyloxy)-5-bromo-3-fluorotetrahydrofuran-2-yl)methyl benzoate Methyl 3-deoxy-3-fluoro-β-D-arabinofuranoside methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-threo-pentofuranoside methyl 5-O-benzoyl-2-chloro-2,3-dideoxy-3-fluoro-β-D-ribofuranoside (2R,3S)-5,5-bis(benzyloxy)-3-fluoro-2-hydroxypentyl acetate 2,2-Dimethyl-propionic acid (2R,3S,5R)-3-fluoro-5-phenylsulfanyl-tetrahydro-furan-2-ylmethyl ester ((2R,3R,4S)-4-chloro-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate 2-((2R,3S,5R)-3-Fluoro-5-phenylsulfanyl-tetrahydro-furan-2-ylmethoxy)-4-methoxy-5-methyl-pyrimidine 5'-O-TBDPS-dT 5’-O-Trityl-3’-β-hydroxythymidine O,O′-二(三甲基甲硅烷基)胸苷 3'-Tosyl-5'-O-trityl thymidine 胸苷