百科

21-羟基-5Alpha-孕甾(烷)-3,20-二酮

CAS号：298-36-2

英文名：(5S,8R,9S,10S,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

分子式

C21H32O3

熔点

密度

1.11g/cm3

分子量

332.477

沸点

468.6ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

5α-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5α-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects.

基本信息

中文名称

21-羟基-5Alpha-孕甾(烷)-3,20-二酮

英文名称

(5S,8R,9S,10S,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

中文别名

英文别名

5alpha-Pregnan-21-ol-3,20-dione、5alpha-Dihydro-11-deoxycorticosterone、Pregnane-3,20-dione,21-hydroxy-,(5alpha)、Allopregnane-21-ol-3,20-dione、21-Hydroxy-5alpha-pregnane-3,20-dione、5alpha-Dihydrodeoxycorticosterone、5alpha-Pregnane-3,20-dione,21-hydroxy

CAS号

298-36-2

分子式

C21H32O3

分子量

332.477

精确质量

332.235

PSA

54.37

LOGP

3.7758