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醋酸去氧皮质酮

CAS号：56-47-3

英文名：21-(acetyloxy)-pregn-4-ene-3,20-dione

分子式

C23H32O4

熔点

157°C

密度

1.14 g/cm3

分子量

372.498

沸点

504.1ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Adrenocortical/mineralocorticoid Steroid.

基本信息

中文名称

醋酸去氧皮质酮

英文名称

21-(acetyloxy)-pregn-4-ene-3,20-dione

中文别名

乙酸脱氧皮质甾酮、醋酸脱氧皮质酮、乙酸-11-脱氧皮质甾酮、21-乙酸羟基孕酮

英文别名

[2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

CAS号

56-47-3

分子式

C23H32O4

分子量

372.498

精确质量

372.23

PSA

60.44

LOGP

4.2667

编号系统

MDL号

MFCD00003660

物化性质

外观与性状

白色固体

密度

1.14 g/cm3

沸点

504.1ºC at 760 mmHg

熔点

157°C

闪点

218ºC

折射率

175 ° (C=1, Dioxane)

稳定性

Stable at normal temperatures and pressures.

储存条件

Keep tightly closed.

安全信息

RTECS号

HG0525000

安全说明

S22-S24/25

WGK Germany

危险品运输编码

UN 2811

危险类别

6.1

包装等级

生产方法及用途

生产方法

黄体酮在四氢呋喃和甲醇混合溶液中与氧化钙和碘发生碘代反应，再与醋酸钾在无水丙酮中反应成酯，最后精制而得。

用途

羟孕酮琥酯钠的中间体。生化研究，肾上腺皮质激素类药物，具有抗炎、抗过敏等作用。

合成路线

上游原料

21-acetoxy-3β-formyloxy-pregn-5-en-20-one

104203-44-3

21-Benzoyloxy-4-pregnen-3,20-dion-3-ethylendithioacetal

33439-96-2

3β.5.14.21-tetrahydroxy-3β.14β-pregnanone-(20)

104203-45-4

21-Benzoyloxy-4-pregnen-3,20-dion

7726-95-6

溴

25312-77-0

3,20,23-trioxo-21-nor-chol-4-en-24-oic acid

下游产品

共找到7个下游商品 >

111464-71-2

4,5-epoxy-21-hydroxypregnane-3,20-dione

302-97-6

3-氧代-雄甾-4-烯-17beta-羧酸

567-02-2

3alpha,21-二羟基-5alpha-孕甾-20-酮

21-羟基-5Alpha-孕甾(烷)-3,20-二酮

上游原料

21-acetoxy-3β-formyloxy-pregn-5-en-20-one 21-Benzoyloxy-4-pregnen-3,20-dion-3-ethylendithioacetal 3β.5.14.21-tetrahydroxy-3β.14β-pregnanone-(20) 21-Benzoyloxy-4-pregnen-3,20-dion 溴 3,20,23-trioxo-21-nor-chol-4-en-24-oic acid 21-乙酰氧基孕烯醇酮 3β-acetoxy-Δ5-etiocholenic acid chloride 盐酸 3,20,23-trioxo-21-nor-chol-4-en-24-oic acid ethyl ester 20-acetoxy-3β-formyloxy-pregna-5,16,20-triene 20ξ-hydroxy-3-oxo-pregnen-(4)-al-(21) (3S,8S,9S,10R,13R,14S,17S)-3-acetyloxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid 乙酸钾吡啶乙酸铅(IV) 21-acetoxy-3β-formyloxy-pregna-5,16-dien-20-one 乙酸钠 21-chloro-5β-pregnane-3,20-dione 21-diazo-3β-hydroxy-pregn-5-en-20-one 醋酸 3β-formyloxy-21-iodo-pregna-5,16-dien-20-one 乙醇醋酸乙烯酯乙酸酐 20ξ-cyano-20ξ-hydroxy-4-pregnen-3-one 21-氯黄体酮 (8S,9S,10R,13S,14S,17R)-17-(5,5-diphenylpenta-2,4-dien-2-yl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one 3β-hydroxypregn-5-ene-16,20-dione 黄体酮 16-dehydropregnenoloneformate 四氯化碳去氧皮质酮 [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate N-溴代丁二酰亚胺乙烯酮 3,3-ethanediyldioxy-20-hydroxy-23,24-dinor-20ξH-chol-5-ene-21-nitrile 2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde 1-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-yl)ethanone 21-重氮基孕甾-4-烯-3,20-二酮 11-deoxy-21-iodocorticosterone (5beta)-21-(乙酰氧基)孕甾烷-3,20-二酮

下游产品

4,5-epoxy-21-hydroxypregnane-3,20-dione 3-氧代-雄甾-4-烯-17beta-羧酸 3alpha,21-二羟基-5alpha-孕甾-20-酮去氧皮质酮孕甾二醇 21-羟基-5Alpha-孕甾(烷)-3,20-二酮 (5R,8R,9S,10S,13S,14S,17S)-17-(2-羟基乙酰基)-10,13-二甲基-1,2,4,5,6,7,8,9,11,12,14,15,16,17-十四氢环戊烯并[a]菲-3-酮