百科

骨化三醇

骨化三醇

CAS号：32222-06-3

英文名：calcitriol

分子式：C27H44O3

分子量：416.636

合成路线

(1R,6R,7R)-7-[(R)-6-(methoxymethoxy)-6-methylheptan-2-yl]-6-methylbicyclo[4.3.0]nonan-2-one

(1R,6R,7R)-7-[(R)-6-(methoxymethoxy)-6-methylheptan-2-yl]-6-methylbicyclo[4.3.0]nonan-2-one

骨化三醇

[S-(1α,3α,5α)]-(1,1-dimethylethyl)[(1-ethynyl-2-methylenebicyclo[3.1.0]hexan-3-yl)oxy]diphenylsilane

[S-(1α,3α,5α)]-(1,1-dimethylethyl)[(1-ethynyl-2-methylenebicyclo[3.1.0]hexan-3-yl)oxy]diphenylsilane

骨化三醇

<1R-<1α(R*),3aβ,4α(1S*,3S*,5S*),7aα>>-4-<<3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-2-methylenebicyclo<3.1.0>hexan-1-yl>ethynyl>octahydro-7a-methyl-1-<1,5,5-trimethyl-5-((trimethylsilyl)oxy)pentyl>-1H-inden-4-ol

<1R-<1α(R*),3aβ,4α(1S*,3S*,5S*),7aα>>-4-<<3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-2-methylenebicyclo<3.1.0>hexan-1-yl>ethynyl>octahydro-7a-methyl-1-<1,5,5-trimethyl-5-((trimethylsilyl)oxy)pentyl>-1H-inden-4-ol

骨化三醇

<1R-<1α(R*),3aβ,4α<(E)-(1S*,3S*,5R*)>,7aα>>-1-<1,5-dimethyl-5-<(trimethylsilyl)oxy>hexyl>-4-<2-<3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-2-methylenebicyclo<3.1.0>hexan-1-yl>ethenyl>octahydro-7a-methyl-1H-inden-4-ol

<1R-<1α(R*),3aβ,4α<(E)-(1S*,3S*,5R*)>,7aα>>-1-<1,5-dimethyl-5-<(trimethylsilyl)oxy>hexyl>-4-<2-<3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-2-methylenebicyclo<3.1.0>hexan-1-yl>ethenyl>octahydro-7a-methyl-1H-inden-4-ol

骨化三醇

(1S,3S,5S)-1-乙炔基-2-亚甲基双环[3.1.0]己烷-3-醇

(1S,3S,5S)-1-乙炔基-2-亚甲基双环[3.1.0]己烷-3-醇

骨化三醇

(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-20(S)-(hydroxymethyl)-9,10-secopregna-5(E),7(E),10(19)-triene

(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-20(S)-(hydroxymethyl)-9,10-secopregna-5(E),7(E),10(19)-triene

骨化三醇

1(S),3(R)-bis[(tert-butyldimethylsilyl)oxy]-20(S)-(iodomethyl)-9,10-seco-27-norcholesta-5(E),7(E),10(19)triene

1(S),3(R)-bis[(tert-butyldimethylsilyl)oxy]-20(S)-(iodomethyl)-9,10-seco-27-norcholesta-5(E),7(E),10(19)triene

骨化三醇

ethyl (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-seco-26,27-bisnorcholesta-5(E),7(E),10(19)-trien-25-oate

ethyl (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-seco-26,27-bisnorcholesta-5(E),7(E),10(19)-trien-25-oate

骨化三醇

(2S)-2-((1R,3aS,7aR,E)-4-(((6S)-2,2-dioxido-6-((triethylsilyl)oxy)-1,3,4,5,6,7-hexahydrobenzo[c]thiophen-1-yl)methylene)-7a-methyloctahydro-1H-inden-1-yl)propanal

(2S)-2-((1R,3aS,7aR,E)-4-(((6S)-2,2-dioxido-6-((triethylsilyl)oxy)-1,3,4,5,6,7-hexahydrobenzo[c]thiophen-1-yl)methylene)-7a-methyloctahydro-1H-inden-1-yl)propanal

骨化三醇

(6S)-1-(((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)methyl)-6-((triethylsilyl)oxy)-1,3,4,5,6,7-hexahydrobenzo[c]thiophene 2,2-dioxide

(6S)-1-(((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)methyl)-6-((triethylsilyl)oxy)-1,3,4,5,6,7-hexahydrobenzo[c]thiophene 2,2-dioxide

骨化三醇

查看更多

上游原料

25-hydroxy-de-A,B-cholest-8-en-8-yl trifluoromethanesulfonate (1S-cis)-(1,1-dimethylethoxy)-2,3,5,6,7,7a-hexahydro-7a-methyl-5-oxo-1H-indene-4-carboxylic acid (3S,5R)-3,5-bis[((tert-butyldiphenyl)silyl)oxy]-1-ethynyl-2-methylcyclohex-1-ene [2S-(1E,2α,3β,5α)]-(2,3,5-trihydroxy-2-methylcyclohexylidene)acetic acid ethyl ester [S-(1α,2β,5α)]-1-[(trimethylsilyl)ethynyl]bicyclo[3.1.0]hexan-2-ol α-Phenyl-β-(methanesulfonyl)ethanesulfonyl chloride 1-((1S,3aR,7aS)-1-(tert-butoxy)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl)ethan-1-one (3S,5R)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene [1R-(1α,2E,4α,6α)]-[1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]hept-2-ylidene]acetic acid ethyl ester [3S-(1Z,3α,5β)]-2-[3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]-1-chloroethane (1S,2R,4S,6S)-2,4-diacetoxy-2-ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane (1S-cis)-1-<(trimethylsilyl)ethynyl>bicyclo<3.1.0>hexan-2-one (1S,3aR,4R,7aS)-1-(tert-butoxy)-7a-methyloctahydro-1H-inden-4-yl acetate 1α-<((tert-butyldiphenyl)silyl)oxy>-6,7-dehydro-25-hydroxyprevitamin D3 (tert-butyldiphenyl)silyl ether 骨化三醇杂质 [2S-(1E,2α,3β,5α)]-[2,3-bis(acetyloxy)-2-methyl-5-(1-methylethenyl)cyclohexylidene]acetic acid ethyl ester ethyl (R,E)-4-((3aS,7R,7aR)-7-acetoxy-3a-methyl-3a,4,5,6,7,7a-hexahydro-1H-inden-3-yl)pent-2-enoate (1S,3R,5E,7E,14Xi)-1,3-二{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-9,10-开链胆甾-5,7,10-三烯-25-醇 (3aR,4R,7aS)-7a-methyl-1-oxooctahydro-1H-inden-4-yl acetate [3aR-((E), 3aα,4β,7aβ)]-1-ethylidene-octahydro-7a-methyl-1H-4-indenol [1R-[1α(R*),3aβ,7aα]]-octahydro-1-[5-[(trimethylsilyl)oxy]-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-one [2S-(1E,2α,3β,5α)]-[3,5-bis[[(1,1dimethylethyl)dimethylsilyl]oxy]-2-hydroxy-2-methylcyclohexylidene]acetic acid ethyl ester 1,1-dimethoxy-3-(tert-diphenylsiloxy)-5-hexyne de-A,B-25-cholesta-8,25-dien-8-yl trifluromethanesulfonate 1-((1S,3aS,4S,5S,7aS)-1-(tert-butoxy)-5-hydroxy-7a-methyloctahydro-1H-inden-4-yl)ethan-1-one 3-((tert-butyldiphenylsilyl)oxy)hex-5-ynal 甲基锂 (3S,5R)-3,5-bis<((tert-butyldiphenyl)silyl)oxy>-1-ethenyl-2-methylcyclohex-1-ene (1S,6R)-1-hydroxy-6-(1,3-benzodithiol-2-yloxy)-25-tetrahydropyranyloxy-3,5-cyclovitamin D3 (R)-2-[(trimethylsilyl)ethynyl]-2-cyclopenten-1-ol (1S,3aS,4S,5S,7aS)-1-(tert-butoxy)-5-hydroxy-7a-methyloctahydro-1H-indene-4-carboxylic acid (1R-cis)-trimethyl((2-methylenebicyclo(3.1.0)hexyl)ethynyl)silane (+/-)-1β-tert.-Butoxy-3aα,4β,5,6,7,7a-hexahydro-7aβ-methyl-5-oxo-4-indancarbonsaeure (((1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-(methoxymethoxy)-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diyl)bis(oxy))bis(triisopropylsilane) (2S-(1E,2α,3β,5α))-(2,3,5-tris(acetyloxy)-2-methylcyclohexylidene)acetic acid ethyl ester 1,1-diethoxy-3-(tert-butyldiphenylsiloxy)-5-hexyne 1-((1S,3aS,4R,7aS)-1-(tert-butoxy)-7a-methyloctahydro-1H-inden-4-yl)ethan-1-one (3S,5R)-3,5-bis[((tert-butyldiphenyl)silyl)oxy]-1-(2,2-dibromoethenyl)-2-2-methylcyclohex-1-ene 1,1-diethoxy-3-hydroxy-5-hexyne 7,8-cis-1α,25-dihydroxyvitamin D3 (3aR,4R,7aS,Z)-1-ethylidene-7a-methyloctahydro-1H-inden-4-yl acetate [2S-(1E,2α,3β,5α)]-[5-acetyl-2,3-bis(acetyloxy)-2-methyl-cyclohexylidene]acetic acid ethyl ester 25-oxo-27-nor-1α(OH)D3 [1S-(1β,3aα,4β,7aβ)]-7a-methyl-octahydro-1H-indene-1,4-diol 4-acetate

下游产品

骨化三醇杂质