化合物简介
Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent, related to moracizine. It is used in Russia and some other CIS countries for the treatment of severe and/or refractory ventricular and supraventricular arrhythmias, especially those accompanied by organic heart disease. It is also indicated as a treatment of refractory tachycardia associated with Wolff–Parkinson–White syndrome.
基本信息
中文名称
N-[10-(3-二乙基氨基丙酰基)吩噻嗪-2-基]氨基甲酸乙酯
英文名称
ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate
中文别名
英文别名
Ethacizin、Ethmozine DAA、Etmozine DAA、Ethacizine、ethyl[10-(n,n-diethyl-|A-alanyl)-10h-phenothiazin-2-yl]carbamate、Ethacyzin、EZ 55、Etacizin
CAS号
33414-33-4
分子式
C22H27N3O3S
分子量
413.533
精确质量
413.177
PSA
87.18
LOGP
5.2542
编号系统
UNII
FE5SPV1Z6G
物化性质
密度
1.239g/cm3
沸点
576.7ºC at 760mmHg
闪点
302.6ºC
折射率
1.623
合成路线