化合物简介
Adrenosterone is a steroid hormone with weak androgenic effect. It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of Basel. Originally, adrenosterone was called Reichstein's substance G. Adrenosterone occurs in trace amounts in humans as well as most mammals and in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone.
基本信息
中文名称
肾上腺甾酮
英文名称
Adrenosterone
中文别名
雄甾-4-烯-3,11,17-三酮、4-雄烯-3,11,17-三酮、ADRENOSTERONE (11-OXO)
英文别名
Reichstein’s substance G、androst-4-ene-3,11,17-trione、Androst-4-ene-3,11,17-trione、11-KETOANDROSTENEDIONE、4-androsten-11-keto-3,17-dione、Reichstein\'s Substance G、Andrenosterone、11-Ketoandrostenedione、Androsten-(4)-trion-(3.11.17)、Androst-4-en-3,11,17-trion、REICHSTEIN\'S \'G\'、4-androsten-11,3,17-trione、11-Oxy-4-androstenedione、4-androstene-3,11,17-trione、4-ANDROSTEN-3,11,17-TRIONE、REICHSTEIN\'S SUBSTANCE G、4-Androstene-3,11,17-trione
CAS号
382-45-6
分子式
C19H24O3
分子量
300.392
精确质量
300.173
PSA
51.21
LOGP
3.2664
编号系统
MDL号
MFCD00003606
物化性质
外观与性状
灰白色至淡黄色固体
密度
1.18g/cm3
沸点
476.1ºC at 760mmHg
熔点
219-222°C(lit.)
闪点
206ºC
折射率
290 ° (C=0.2, EtOH)
安全信息
WGK Germany
3
海关编码
2942000000
生产方法及用途
用途
优质医药原料。
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