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2',3',5'-三乙酰尿苷

2',3',5'-三乙酰尿苷

CAS号：4105-38-8

英文名：2',3',5'-Tri-O-acetyluridine

分子式

C15H18N2O9

熔点

124-134ºC

密度

1.43g/cm3

分子量

370.311

沸点

溶解度

信号词

危险品标志

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化合物简介

2’,3’,5’-Triacetyluridine is used in the treatment of Alzheimer’s disease in mice and provide neuroprotective effects. Shown to also decrease depressive symptoms and increases in brain pH bipolar patients.

基本信息

中文名称

2',3',5'-三乙酰尿苷

英文名称

2',3',5'-Tri-O-acetyluridine

中文别名

2’,3’,5’-三乙酰尿苷、2,3,5-三乙酰尿苷

英文别名

Uridine, 2‘,3‘,5‘-triacetate、2\',3\',5\'-Tri-O-acetyl-rU、2’,3’,5’-Triacetyluridine、2`,3`,5`-Tracetyluridine、Uridine 2\',3\',5\'-Triacetate、TAU、2\',3\',5\'-Tri-O-acety、Tri-O-acetyl uridine、2\',3\',5\'-Tri0acetyluridine、(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate、Uridine triacetate、O2\',O3\',O5\'-triacetyl-uridine、2\',3\',5\'-O-triacetyluridine、2`,3`,5`-Triacetyluridine、2\',3\',5\'-trioacetyluridine、Vistonuridine

CAS号

4105-38-8

分子式

C15H18N2O9

分子量

370.311

精确质量

370.101

PSA

142.99

LOGP

-1.1395

编号系统

UNII

2WP61F175M

物化性质

外观与性状

白色或近乎于白色结晶粉末

密度

1.43g/cm3

熔点

124-134ºC

折射率

1.552

储存条件

-20ºC

合成路线

共找到19条合成路线 >

乙酸酐

尿嘧啶核苷

尿嘧啶核苷

2',3',5'-三乙酰尿苷

2',3',5'-三乙酰尿苷

上游原料

共找到24个上游原料 >

乙酰氯

乙酸酐

2,3,5-tri-O-acetyl-D-ribofuranosyl 1-(N-phenyl)-2,2,2-trifluoroacetimidate

2,3,5-tri-O-acetyl-D-ribofuranosyl 1-(N-phenyl)-2,2,2-trifluoroacetimidate

cytidine tetraacetate

cytidine tetraacetate

3',5'-O-(1,1,3,3-四异丙基-1,3-二硅氧烷)尿苷

3',5'-O-(1,1,3,3-四异丙基-1,3-二硅氧烷)尿苷

下游产品

共找到20个下游商品 >

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(dimethylamino)pyrimidin-2-one

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(dimethylamino)pyrimidin-2-one

5-乙炔基尿苷

5-乙炔基尿苷

2’-C-甲基胞嘧啶核苷

2’-C-甲基胞嘧啶核苷

5-溴尿苷

5-氯尿嘧啶核苷

5-氯尿嘧啶核苷

上游原料

乙酰氯乙酸酐 2,3,5-tri-O-acetyl-D-ribofuranosyl 1-(N-phenyl)-2,2,2-trifluoroacetimidate 胞苷 cytidine tetraacetate 3',5'-O-(1,1,3,3-四异丙基-1,3-二硅氧烷)尿苷 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(pyridin-3-yloxy)pyrimidin-2(1H)-one 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-((6-methylpyridin-2-yl)oxy)pyrimidin-2(1H)-one 1,2,3,5-四-O-乙酰基-β-D-呋喃核糖 1-((6aR,8R,9R,9aR)-2,2,4,4-tetraisopropyl-9-((trimethylsilyl)oxy)tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(pyridin-2-ylthio)pyrimidin-2(1H)-one 甲醇 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-((6-methylpyridin-3-yl)oxy)pyrimidin-2(1H)-one 2,3,5-tri-O-acetyl-β-D-ribofuranosyl ortho-hexynylbenzoate 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(2-oxopyridin-1(2H)-yl)pyrimidin-2(1H)-one 2,3,5-tri-O-acetylribofuranose (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2,4-dioxo-3-(tritylthio)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate 4-硫代尿苷2’,3’,5’-三乙酸酯 1-trimethylsilylpyrimidine-2,4-dione 尿嘧啶核苷 N3-benzyloxymethyl-2',3',5'-tri-O-acetyl uridine 2',3',5'-tri-O-acetyl-3-nitrouridine 尿嘧啶

下游产品

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(dimethylamino)pyrimidin-2-one 5-乙炔基尿苷 2’-C-甲基胞嘧啶核苷 5-溴尿苷胞苷 5-氯尿嘧啶核苷 5-碘尿苷阿糖尿苷胞苷-5’-三磷酸 5-nitro-2,4(1H,3H)-pyrimidinedione 2-氨基-1-beta-D-呋喃阿拉伯糖基-4(1H)-嘧啶酮 (3aξ,3bξ)-4-(tri-O-acetyl-β-D-ribofuranosyl)-(3ar,3br',7ac',7bc)-tetrahydro-[1,3]dioxolo[4',5':3,4]cyclobuta[1,2-d]pyrimidine-2,5,7-trione 2,2'-脱水尿苷 4-硫代尿苷 5-氟胞嘧啶核苷 1-甲基-5-硝基尿嘧啶 2’,3’-O-异亚丙基-5-氯尿苷 N4-甲基胞苷尿嘧啶核苷 2',3',5'-tri-O-acetyl-3-nitrouridine