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尿嘧啶核苷

尿嘧啶核苷

CAS号：58-96-8

英文名：uridine

分子式

C9H12N2O6

熔点

163-167°C(lit.)

密度

1.674 g/cm3

分子量

244.201

沸点

溶解度

信号词

危险品标志

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化合物简介

尿苷（Uridine）是一种属于核苷的化合物，由尿嘧啶与核糖（呋喃核糖）环组成，两者由β-N1-配糖键相连。

基本信息

中文名称

尿嘧啶核苷

英文名称

uridine

中文别名

1-β-D-Ribofuranosyluracil、尿核苷、尿苷、尿苷,尿核苷

英文别名

NFDB2、Uridine、URD、D-URIDINE、Uridin

CAS号

58-96-8

分子式

C9H12N2O6

分子量

244.201

精确质量

244.07

PSA

124.78

LOGP

-2.8519

编号系统

MDL号

MFCD00006526

物化性质

外观与性状

白色至灰白色结晶粉末

密度

1.674 g/cm3

熔点

163-167°C(lit.)

折射率

9 ° (C=2, H2O)

储存条件

Keep Cold

安全信息

RTECS号

YR1450000

安全说明

S24/25

WGK Germany

3

危险类别码

R36/37/38

海关编码

2934999090

危险类别

6.1

包装等级

I; II; III

危险品标志

Xi

生产方法及用途

生产方法

1.可以用2,4-二氯(三甲基硅氧基)嘧啶制取。

用途

尿苷是一种药物,如抗巨型红血球贫血,治疗肝、脑血管、心血管等疾病,也是制造氟尿嘧啶(S-FC)、脱氧核苷、碘苷(IDUR)、溴苷(BUDR)、氟苷(FUDR)等药物的主要原料。

合成路线

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3'-amino-3'-deoxyuridylyl-3',5'-uridine

3'-amino-3'-deoxyuridylyl-3',5'-uridine

尿苷5-单磷酸

尿苷5-单磷酸

1-((2R,3R,4S,5S)-4-amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3R,4S,5S)-4-amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

尿嘧啶核苷

尿嘧啶核苷

3'-amino-3'-deoxyuridine 2'-phosphate

3'-amino-3'-deoxyuridine 2'-phosphate

海关数据

共找到8个国家海关数据 >

国家/地区名称	海关编码	更新时间	操作
中国	2934999090	2019-03	查看
美国	2934999000	2019-03	查看
印度	29349900	2019-03	查看
欧盟	29349990	2019-03	查看
英国	2934999090	2019-03	查看
日本	293499090	2019-03	查看
韩国	2934999000	2019-03	查看
加拿大	2934990090	2019-03	查看

上游原料

共找到128个上游原料 >

[5-(6-氨基嘌呤-9-基)-4-羟基-2-(羟基甲基)四氢呋喃-3-基][5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲基磷酸氢酯

[5-(6-氨基嘌呤-9-基)-4-羟基-2-(羟基甲基)四氢呋喃-3-基][5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲基磷酸氢酯

3',5'-di(t-butyldimethylsilyl)-β-uridine

3',5'-di(t-butyldimethylsilyl)-β-uridine

1-(2'-O-acetamidomercaptocarbonyl-3',5'-di-O-benzoyl-β-D-ribo-furanosyl)uracil

1-(2'-O-acetamidomercaptocarbonyl-3',5'-di-O-benzoyl-β-D-ribo-furanosyl)uracil

1-[(2R,3S,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione

1-[(2R,3S,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione

1-[2,2-dibutyl-6-(hydroxymethyl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxastannol-4-yl]pyrimidine-2,4-dione

1-[2,2-dibutyl-6-(hydroxymethyl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxastannol-4-yl]pyrimidine-2,4-dione

2'-O-[5-(dimethylamino)naphthalene-1-sulfonamidyl-N-oxymethyl]uridine

2'-O-[5-(dimethylamino)naphthalene-1-sulfonamidyl-N-oxymethyl]uridine

下游产品

共找到141个下游商品 >

(5R,6S)-1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-6-hydroxy-dihydro-pyrimidine-2,4-dione

(5R,6S)-1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-6-hydroxy-dihydro-pyrimidine-2,4-dione

Uridine, 2'-carbamate

Uridine, 2'-carbamate

2’-C-甲基胞嘧啶核苷

2’-C-甲基胞嘧啶核苷

1-[(2R,3R,4S,5S)-5-(bromomethyl)-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione

1-[(2R,3R,4S,5S)-5-(bromomethyl)-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione

尿苷-5'-三磷酸

尿苷-5'-三磷酸

1-[(2R,3R,4S,5R)-3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]-3-(2-氧代-2-苯基乙基)嘧啶-2,4-二酮

1-[(2R,3R,4S,5R)-3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]-3-(2-氧代-2-苯基乙基)嘧啶-2,4-二酮

上游原料

[5-(6-氨基嘌呤-9-基)-4-羟基-2-(羟基甲基)四氢呋喃-3-基][5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲基磷酸氢酯 3',5'-di(t-butyldimethylsilyl)-β-uridine 1-(2'-O-acetamidomercaptocarbonyl-3',5'-di-O-benzoyl-β-D-ribo-furanosyl)uracil 1-[(2R,3S,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione 1-[2,2-dibutyl-6-(hydroxymethyl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxastannol-4-yl]pyrimidine-2,4-dione 2'-O-[5-(dimethylamino)naphthalene-1-sulfonamidyl-N-oxymethyl]uridine 1-(2,3-O-ethoxymethylidene-β-D-ribofuranosyl)uracil 2’,3’邻异亚丙基尿苷 2'-O-[2-(methoxycarbonyl)ethyl]uridine 尿嘧啶 5’-O-(4,4’-二甲氧基三苯甲基)尿苷 N-(2-(((((2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)methoxy)imino)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide N3,2',3'-O-tris-(benzyloxycarbonyl)uridine 3',5'-O-(1,1,3,3-四异丙基-1,3-二硅氧烷)尿苷 2′,3′-O-bis-(benzyloxycarbonyl)uridine 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(pyridin-3-yloxy)pyrimidin-2(1H)-one 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-[(4-methoxyphenyl)methoxy]oxolan-2-yl]pyrimidine-2,4-dione 1-((6aR,8R,9R,9aR)-2,2,4,4-tetraisopropyl-9-((trimethylsilyl)oxy)tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]oxolan-2-yl]pyrimidine-2,4-dione 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-((6-methylpyridin-3-yl)oxy)pyrimidin-2(1H)-one 2,3,5-三苯甲酰尿苷 3'-O-(tert-butyldimethylsilyl)uridine 1-{(2R,3R,4R,5R)-3,4-Bis-(2-methoxy-ethoxymethoxy)-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-3-(2-methoxy-ethoxymethyl)-1H-pyrimidine-2,4-dione 5'-O-tert-butyldimethylsilyl-2',3'-O-bis(benzyloxycarbonyl)uridine 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(2-oxopyridin-1(2H)-yl)pyrimidin-2(1H)-one 2'-O-叔丁基二甲基硅烷基尿苷 2'-O-allyluridine 3-N-(2-nitrobenzene)sulfenyluridine 2',5'-bis-O-(tert-butyldimethylsilyl)uridine uridine-5'-monothiophosphate uridylyl(2',5')uridine 尿苷酰基-(3',5')-尿苷 N3,O2',O3'-tris((methoxyethoxy)methyl)uridine 烯丙基三甲基硅烷 3'-amino-3'-deoxyuridylyl-3',5'-uridine 1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖 2'-O-{[(triisopropylsilyl)oxy]methyl}uridine 5’-O-三苯甲基尿苷 2',3'-O-Isopropylidene uridine 5'-O-tosylate 2',3',5'-三乙酰尿苷 R1P 5-(dimethylamino)-N-(4-(((((2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)methoxy)imino)butyl)naphthalene-1-sulfonamide Uridine, 3-[(2-methoxyethoxy)methyl]- 胞苷 [3,4-bis(benzoyloxy)-5-chlorooxolan-2-yl]methyl benzoate 5-(dimethylamino)-N-(2-(((((2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)methoxy)imino)ethyl)naphthalene-1-sulfonamide 5-碘尿苷 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-((6-methylpyridin-2-yl)oxy)pyrimidin-2(1H)-one 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(pyridin-2-ylthio)pyrimidin-2(1H)-one

下游产品

(5R,6S)-1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-6-hydroxy-dihydro-pyrimidine-2,4-dione Uridine, 2'-carbamate 2’-C-甲基胞嘧啶核苷 1-[(2R,3R,4S,5S)-5-(bromomethyl)-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione 尿苷-5'-三磷酸 1-[(2R,3R,4S,5R)-3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]-3-(2-氧代-2-苯基乙基)嘧啶-2,4-二酮 6-O-甲基-鸟苷 5'-O-(5''-amino-5''-deoxy-β-D-ribosyl)uridine 2’,3’邻异亚丙基尿苷 2,2'-Anhydrouridine 3'-carbamate N(3)-苄基尿苷 [5-(6-aminopurin-9-yl)-3-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate 3-O-甲基尿苷 5-氟尿嘧啶核苷尿嘧啶尿苷-5’-二磷酸尿苷酰基-(2'-5')-腺苷 [(2R,3S,4R,5R)-5-(6-氨基嘌呤-9-基)-3,4-二羟基四氢呋喃-2-基]甲基[(2R,3S,4R,5R)-5-(2,4-二氧代嘧啶-1-基)-4-羟基-2-(羟基甲基)四氢呋喃-3-基]磷酸氢酯 5'-O-levulinoyl-β-L-uridine 5-羟甲基尿苷 5'-O,6-Cyclo-5,5-dibromo-5,6-dihydrouridine [3,4-dibenzoyloxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methyl benzoate 5'-脱氧-5'-碘尿苷 (4R,5S)-3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoro-2,6-dioxohexahydropyrimidin-4-yl acetate 尿苷酸二钠尿嘧啶核苷 D-核糖 uridine-5'-monothiophosphate 腺苷 5-溴尿苷 Uridine, 3'-carbamate 5'-O-levulinoyl-β-D-uridine 5'-chloro-5'-deoxyuridine 阿糖尿苷 6-苄基腺苷 2',3',5'-三乙酰尿苷 2,2'-脱水尿苷 R1P 6-氯嘌呤核苷 α-D-ribofuranosyl phosphate, free acid 2'-甲氧基尿苷 2-deoxy-α-D-ribofuranose 1-phosphate 胞苷 Uridine 2',3'-carbonate 利巴韦林 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-3-methylpyrimidine-2,4-dione 1-[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]-1,3-diazinane-2,4-dione 尿苷5-单磷酸 2-(hydroxymethyl)-5-(6-iodopurin-9-yl)oxolane-3,4-diol