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N-去甲基加兰它敏氢溴酸盐

N-去甲基加兰它敏氢溴酸盐

CAS号：41303-74-6

英文名：N-Desmethyl Galanthamine

分子式

C16H19NO3

熔点

142-145ºC

密度

1.309g/cm3

分子量

273.327

沸点

457.923ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor.

基本信息

中文名称

N-去甲基加兰它敏氢溴酸盐

英文名称

N-Desmethyl Galanthamine

中文别名

氮位N-脱甲基加兰他敏、N-去甲基加兰他敏

英文别名

N-Norgalanthamine、N-Demethylgalantamine、Norgalantamine、N-desmethyl galantamine、UNII-2BPQ4IVQ21

CAS号

41303-74-6

分子式

C16H19NO3

分子量

273.327

精确质量

273.136

PSA

50.72

LOGP

1.8369

物化性质

密度

1.309g/cm3

沸点

457.923ºC at 760 mmHg

熔点

142-145ºC

闪点

230.744ºC

折射率

1.642

储存条件

-20ºC Freezer

合成路线

共找到1条合成路线 >

(4aS,6R,8aS)-3-methoxy-5,6,9,10-tetrahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol

(4aS,6R,8aS)-3-methoxy-5,6,9,10-tetrahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol

N-去甲基加兰它敏氢溴酸盐

N-去甲基加兰它敏氢溴酸盐

上游原料

共找到17个上游原料 >

加兰他敏

(2R,11bR)-2-benzyl-8,10-bis(benzyloxy)-9-methoxy-1-(2,2,2-trifluoroacetyl)-1,5,6,11b-tetrahydrospiro[benzo[c]imidazo[1,2-a]azepine-7,1'-cyclohexane]-2',5'-diene-3,4'(2H)-dione

(2R,11bR)-2-benzyl-8,10-bis(benzyloxy)-9-methoxy-1-(2,2,2-trifluoroacetyl)-1,5,6,11b-tetrahydrospiro[benzo[c]imidazo[1,2-a]azepine-7,1'-cyclohexane]-2',5'-diene-3,4'(2H)-dione

(4aS,8aS,13R,14aR)-13-benzyl-2-hydroxy-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepine-6,12(13H)-dione

(4aS,8aS,13R,14aR)-13-benzyl-2-hydroxy-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepine-6,12(13H)-dione

galanthamine N-oxide

galanthamine N-oxide

(4aS,8aS,13R,14aR)-13-benzyl-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepine-6,12(13H)-dione

(4aS,8aS,13R,14aR)-13-benzyl-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepine-6,12(13H)-dione

4-methoxy-3,5-bis(phenylmethoxy)benzaldehyde

4-methoxy-3,5-bis(phenylmethoxy)benzaldehyde

下游产品

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加兰他敏

上游原料

加兰他敏 (2R,11bR)-2-benzyl-8,10-bis(benzyloxy)-9-methoxy-1-(2,2,2-trifluoroacetyl)-1,5,6,11b-tetrahydrospiro[benzo[c]imidazo[1,2-a]azepine-7,1'-cyclohexane]-2',5'-diene-3,4'(2H)-dione (4aS,8aS,13R,14aR)-13-benzyl-2-hydroxy-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepine-6,12(13H)-dione galanthamine N-oxide (4aS,8aS,13R,14aR)-13-benzyl-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepine-6,12(13H)-dione 4-methoxy-3,5-bis(phenylmethoxy)benzaldehyde 没食子酸甲酯氢溴酸加兰他敏 3,5-bis(benzyloxy)-4-methoxybenzyl alcohol Methyl 3,5-dihydroxy-4-methoxybenzoate (4aS,6R,8aS)-3-methoxy-5,6,9,10-tetrahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol methyl 4-methoxy-3,5-bis(phenylmethoxy)benzoate (4aS,6R,8aS)-3-甲氧基-11-甲基-5,6,9,10,11,12-六氢-4ah-[1]苯并呋喃并[3a,3,2-ef][2]苯并氮杂卓-6-醇 11-氧化物 (2S,5R)-5-benzyl-2-(3,5-dibenzyloxy-4-methoxyphenyl)-3-[2-(4-hydroxyphenyl)ethyl]imidazolidin-4-one (4aS,8aS,13R,14aR)-13-benzyl-3-methoxy-6,12-dioxo-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,12,13,14,14a-octahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepin-2-yl trifluoromethanesulfonate (2S,5R)-5-benzyl-2-(3,5-dibenzyloxy-4-methoxyphenyl)-3-[2-(4-hydroxyphenyl)ethyl]-1-(2,2,2-trifluoroacetyl)imidazolidin-4-one (4aS,6R,8aS,13R,14aR)-13-benzyl-6-hydroxy-3-methoxy-14-(2,2,2-trifluoroacetyl)-4a,5,9,10,14,14a-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]imidazo[1,2-a]azepin-12(13H)-one

下游产品