化合物简介
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
基本信息
中文名称
异秋水仙胺
英文名称
(7S)-1,2,3,9-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-10-one
中文别名
英文别名
(S)-6,7-Dihydro-1,2,3,9-tetramethoxy-7-(methylamino)-benzo[a]heptalen-10(5H)-one、Isodemecolcine
CAS号
4702-33-4
分子式
C21H25NO5
分子量
371.427
精确质量
371.173
PSA
66.02
LOGP
3.3458