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(-)-象牙(洪达木)酮宁

(-)-象牙(洪达木)酮宁

CAS号：4880-88-0

英文名：(-)-Eburnamonine

分子式

C19H22N2O

熔点

174-177°C(lit.)

密度

1.34 g/cm3

分子量

294.391

沸点

441.9ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Vinburnine (or eburnamonine, Vincamone) is a vasodilator. Vincamone is a vinca alkaloid and a metabolite of vincamine.

基本信息

中文名称

(-)-象牙(洪达木)酮宁

英文名称

(-)-Eburnamonine

中文别名

长春布宁

英文别名

(-)-EBURNAMONINE

CAS号

4880-88-0

分子式

C19H22N2O

分子量

294.391

精确质量

294.173

PSA

25.24

LOGP

3.7125

编号系统

UNII

G54D0HMY25

物化性质

外观与性状

白色粉末

密度

1.34 g/cm3

沸点

441.9ºC at 760 mmHg

熔点

174-177°C(lit.)

闪点

221ºC

安全信息

RTECS号

YY8575570

安全说明

S22-S24/25

WGK Germany

2

海关编码

2933990090

合成路线

14,15-dihydro-1,14-seco-eburnamenin-14-ol

14,15-dihydro-1,14-seco-eburnamenin-14-ol

(-)-象牙(洪达木)酮宁

(-)-象牙(洪达木)酮宁

上游原料

共找到74个上游原料 >

(4R,5S)‐4‐methyl‐3‐pent‐4‐enoyl‐5‐phenyloxazolidin‐2‐one

(4R,5S)‐4‐methyl‐3‐pent‐4‐enoyl‐5‐phenyloxazolidin‐2‐one

(2S)-(2-ethyl-5-hydroxypentyl)-α-(methoxycarbonyl)acetate

(2S)-(2-ethyl-5-hydroxypentyl)-α-(methoxycarbonyl)acetate

(R)-4-Ethyl-4-((S)-2-methoxymethyl-pyrrolidine-1-carbonyl)-3-trimethylsilanyl-cyclohexa-2,5-dienone

(R)-4-Ethyl-4-((S)-2-methoxymethyl-pyrrolidine-1-carbonyl)-3-trimethylsilanyl-cyclohexa-2,5-dienone

(4S)-N-[2-(indol-3-yl)-ethyl]-4-ethyl-4-hydroxymethyl-6-hydroxyhexamide

(4S)-N-[2-(indol-3-yl)-ethyl]-4-ethyl-4-hydroxymethyl-6-hydroxyhexamide

(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo(2,3-a)quinolizine(1β-yl) pyruvate oxime

(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo(2,3-a)quinolizine(1β-yl) pyruvate oxime

(1S,12bS)-1-ethyl-1-(2-tert-butyldiphenylsilyloxyethyl)-4-oxo-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine

(1S,12bS)-1-ethyl-1-(2-tert-butyldiphenylsilyloxyethyl)-4-oxo-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine

上游原料

(4R,5S)‐4‐methyl‐3‐pent‐4‐enoyl‐5‐phenyloxazolidin‐2‐one (2S)-(2-ethyl-5-hydroxypentyl)-α-(methoxycarbonyl)acetate (R)-4-Ethyl-4-((S)-2-methoxymethyl-pyrrolidine-1-carbonyl)-3-trimethylsilanyl-cyclohexa-2,5-dienone (4S)-N-[2-(indol-3-yl)-ethyl]-4-ethyl-4-hydroxymethyl-6-hydroxyhexamide (-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo(2,3-a)quinolizine(1β-yl) pyruvate oxime (1S,12bS)-1-ethyl-1-(2-tert-butyldiphenylsilyloxyethyl)-4-oxo-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine 色胺 3-((S)-3-Ethyl-5-oxo-tetrahydro-furan-3-yl)-N-[2-(1H-indol-3-yl)-ethyl]-propionamide 长春胺 (S,E)-3-ethyl-3-(2-nitrovinyl)tetrahydro-2H-pyran-2-one (S)-2-ethylpent-4-enoic acid (2S)-[5-(t-butyldiphenylsilyloxy)-2-ethylpentyl]-α-(methoxycarbonyl)acetate (2S)-2-ethyl-4-penten-1-ol (4R,5S)-3[(2R)-2-((1R*)-1-hydroxyethyl)-1-oxo-4-pentenyl]-4-methyl-5-phenyl-2-oxazolidinone 3-(3-ethyl-2-methoxy-3-tetrahydrofuryl)propionic acid (4R,5S)-3-[(2S)-1-oxo-2-ethyl-4-pentenyl]-4-methyl-5-phenyl-2-oxazolidinone 埃那胺 2-ethyl-2-(3-hydroxypropyl)-4-butanolide (2S)-[5-(tert-butyldiphenylsilyloxy)-2-ethylpentyl]-α-diazo-α-(methoxycarbonyl)acetate (S)-N-(2-(1H-indol-3-yl)ethyl)-4-ethyl-4-(hydroxymethyl)hex-5-enamide (41'S,13a'R)-13a'-ethyl-3',41',5',6',13',13a'-hexahydrospiro[[1,3]dithiane-2,2'-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin]-12'(1'H)-one N-(2-(1H-indol-3-yl)ethyl)-3-((3R)-3-ethyl-2-oxo-4-(trimethylsilyl)tetrahydrofuran-3-yl)propanamide 3-(3-ethyl-2-oxotetrahydrofuran-3-yl)propanoic acid (1S,12bS)-1-ethyl-1-(2-hydroxyethyl)-4-oxo-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine 13a-ethyl-2,3,5,6,13,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-12(4<sup>1</sup>H)-imine methyl (S)-(2-ethyl-4-pentenyl)malonate (4S)-4-[3-(tert-butyldiphenylsilyloxypropyl)]-4-ethyldihydro-2(3H)-furanone (3aS,3a1S,10bR)-3a-ethyl-5-nitro-2,3,3a,3a1,4,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole Δ14-vincanol (S)-4-Ethyl-4-formyl-hex-5-enoic acid [2-(1H-indol-3-yl)-ethyl]-amide hydroxy-16 dehydro-1 vincadifformine (4R)-4-ethyl-4-((S)-2-(methoxymethyl)pyrrolidine-1-carbonyl)-3-(trimethylsilyl)cyclohexan-1-one 3-((3R)-3-ethyl-2-oxo-4-(trimethylsilyl)tetrahydrofuran-3-yl)propanoic acid (4S)-N-[2-(3-indolyl)-ethyl]-4-ethyl-4-hydroxymethyl-6-tert-butyldiphenylsiloxyhexamide 14,15-dihydro-1,14-seco-eburnamenin-14-ol 3α-epivincamine (4S)-4-[3-(tert-butyldiphenylsilyloxypropyl)]-4-ethyl-3-(methoxycarbonyl)dihydro-2(3H)-furanone (4S)-4-ethyl-4-(3-hydroxypropyl)dihydro-2(3H)-furanone (4R,5S)-3-[(2R)-2((1R*)-1-(phenoxythiocarbonyloxy)ethyl)-1-oxo-4-pentenyl]-4-methyl-5-phenyl-2-oxazolidinone (1S,12bR)-1-ethyl-1-(2-hydroxyethyl)-4-oxo-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine (1S,12bR)-1-ethyl-1-(2-tert-butyldiphenylsilyloxyethyl)-4-oxo-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine (S)-3-(3-ethyl-2-oxotetrahydrofuran-3-yl)propanoic acid (4R)-N-(2-(1H-indol-3-yl)ethyl)-4-ethyl-6-hydroxy-4-(hydroxymethyl)-5-(trimethylsilyl)hexanamide (3S)-3-ethyl-5-hydroxy-3-(3-hydroxypropyl)dihydrofuran-2(3H)-one (4S)-4-ethyl-4-[2-(hydroxycarbonyl)ethyl]dihydro-2(3H)-furanone (5R)-5-ethyl-5-((S)-2-(methoxymethyl)pyrrolidine-1-carbonyl)-6-(trimethylsilyl)oxepan-2-one (1S,12bS)-1-ethyl-1-vinyl-1,2,3,6,7,12b-hexahydroindolo[2,3-a]quinolizin-4(12H)-one eburnamonine-17α-xanthogenate