百科

长春胺

长春胺

CAS号：1617-90-9

英文名：vincamine

分子式

C21H26N2O3

熔点

232ºC (dec.)

密度

1.36 g/cm3

分子量

354.443

沸点

508.9ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It can be synthesized from related alkaloids.

基本信息

中文名称

长春胺

英文名称

vincamine

中文别名

太司尼克酸、长春花素

英文别名

Pervone、Vraap、Angiopac、Perval、Equipur、Vinca、Minorin、methyl 14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate、Vincamine、Decincan、Novicet、Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3α,14β,16α)-、Monorin

CAS号

1617-90-9

分子式

C21H26N2O3

分子量

354.443

精确质量

354.194

PSA

54.7

LOGP

2.8904

编号系统

RTECS号

YY8575000

MDL号

MFCD00078054

PubChem号

24851332

EINECS号

216-576-3

物化性质

外观与性状

白色至近乎于白色细结晶粉末

密度

1.36 g/cm3

沸点

508.9ºC at 760 mmHg

熔点

232ºC (dec.)

闪点

261.6ºC

稳定性

Stable under normal temperatures and pressures.

储存条件

2-8ºC

蒸汽压

0mmHg at 25°C

安全信息

RTECS号

YY8575000

安全说明

S36

危险类别码

R22

WGK Germany

3

危险品标志

Xn

生产方法及用途

用途

可用于治疗脑动脉硬化、脑梗死。

合成路线

共找到6条合成路线 >

hydroxy-16 dehydro-1 vincadifformine

hydroxy-16 dehydro-1 vincadifformine

长春胺

(-)-象牙(洪达木)酮宁

(-)-象牙(洪达木)酮宁

上游原料

共找到61个上游原料 >

ethyl 3-((2-(1H-indol-3-yl)ethyl)amino)propanoate

ethyl 3-((2-(1H-indol-3-yl)ethyl)amino)propanoate

(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo(2,3-a)quinolizine(1β-yl) pyruvate oxime

(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo(2,3-a)quinolizine(1β-yl) pyruvate oxime

(+/-)-ethyl-(1,2,3,4,6,7,12,12bα-octahydro-indolo(2,3-a)quinolizin-1β-yl)pyruvate oxime

(+/-)-ethyl-(1,2,3,4,6,7,12,12bα-octahydro-indolo(2,3-a)quinolizin-1β-yl)pyruvate oxime

(+)-(1α-Ethyl-1,2,3,4,6,7,12,12bα-octahydro-indolo[2,3-a]quinolizin-1β-yl)-propionic acid

(+)-(1α-Ethyl-1,2,3,4,6,7,12,12bα-octahydro-indolo[2,3-a]quinolizin-1β-yl)-propionic acid

(S)-3-ethyl-1-{2-[1-(tert-butoxycarbonyl)-1H-indol-3-yl]ethyl}-3-(3-hydroxypropyl)-2-piperidinone

(S)-3-ethyl-1-{2-[1-(tert-butoxycarbonyl)-1H-indol-3-yl]ethyl}-3-(3-hydroxypropyl)-2-piperidinone

methyl (E)-3-((1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl)-2-(hydroxyimino)propanoate

methyl (E)-3-((1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl)-2-(hydroxyimino)propanoate

下游产品

共找到5个下游商品 >

(3alpha,14beta,16alpha)-14,15-二氢-14-羟基埃那美宁-14-甲醇

(3alpha,14beta,16alpha)-14,15-二氢-14-羟基埃那美宁-14-甲醇

(-)-象牙(洪达木)酮宁

(-)-象牙(洪达木)酮宁

3α-epivincamine

3α-epivincamine

长春西汀

长春胺

上游原料

ethyl 3-((2-(1H-indol-3-yl)ethyl)amino)propanoate (-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo(2,3-a)quinolizine(1β-yl) pyruvate oxime (+/-)-ethyl-(1,2,3,4,6,7,12,12bα-octahydro-indolo(2,3-a)quinolizin-1β-yl)pyruvate oxime (+)-(1α-Ethyl-1,2,3,4,6,7,12,12bα-octahydro-indolo[2,3-a]quinolizin-1β-yl)-propionic acid (S)-3-ethyl-1-{2-[1-(tert-butoxycarbonyl)-1H-indol-3-yl]ethyl}-3-(3-hydroxypropyl)-2-piperidinone methyl (E)-3-((1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl)-2-(hydroxyimino)propanoate α-tert-butyl β-methyl (2S,3R)-3-ethyl-1-[2-(3-indolyl)ethyl]hexahydroquinolate (+/-)-ethyl-(1,2,3,4,6,7,12,12bα-octahydro-indolo(2,3-a)quinolizin-1β-yl)pyruvate oxime Alpneumine G (3R)-3-ethyl-1-([2-(1H-indol-3-yl)ethyl]-3-{[3-(1,1-dimethylethyl)diphenylsilyl]oxy}propyl)-4-hydroxy-2-piperidinone 17-bromo-o-méthylvincamineLEWIN (1R,12bS)-1-ethyl-1-(methoxycarbonyl)-1,2,3,4,6,7,12,12b-octahydroindolo<2,3-a>quinolizine (-)-1β-methoxycarbonylethyl-1α-ethyl-1,2,3,4,6,7,12,12bα-octahydroindolo[2,3-a]quinolizine 色胺 (S)-3-ethyl-4-[(1-phenylethyl)amino]-1-[2-(1H-indol-3-yl)ethyl]-5,6-dihydro-2(1H)-pyridinone (-)-(7R,20S,21S)-vincadifformine (-)-criocerine (3a<sup>1</sup>S,12aS)-11-(2-(2,4-dinitrophenyl)hydrazono)-12a-ethyl-2,3,3a<sup>1</sup>,4,5,11,12,12a-octahydro-1H,10H-3a,9b-diazabenzo[a]naphtho[2,1,8-cde]azulen-10-one (S)-3-ethyl-1-<2-(1H-indol-3-yl)ethyl>-2-oxo-3-piperidine propanoic acid methyl ester 3-(2-溴乙基)吲哚 (+/-)-1α-ethyl-1β-(2'-carboxy-2'-ethoxycarbonylethyl)-1,2,3,4,6,7,12,12bα-octahydro-indolo[2,3-a]quinolizine tert-butyl (S)-3-(2-(3-(3-((tert-butyldiphenylsilyl)oxy)propyl)-3-ethyl-2-oxopiperidin-1-yl)ethyl)-1H-indole-1-carboxylate Eburnamenine-14-carboxylic acid,17,18-didehydro-14,15-dihydro-14-hydroxy-,methyl ester,(3alpha,14beta,16alpha) (3α,16α)-D-homoeburnamonine-14,15-dione 2-({[3-(ethoxycarbonyl)propyl][2-(1H-indol-3-yl)ethyl]amino}carbonyl)butanoic acid ethyl ester 5-ethyl-1-[2-(1H-indol-3-yl)ethyl]-4-hydroxy-6-oxo-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid ethyl ester (3R)-1-(2-(1H-indol-3-yl)ethyl)-3-ethyl-4-hydroxy-3-(3-hydroxypropyl)piperidin-2-one O-((3R)-1-(2-(1H-indol-3-yl)ethyl)-3-(3-((tert-butyldiphenylsilyl)oxy)propyl)-3-ethyl-2-oxopiperidin-4-yl) S-methyl carbonodithioate dimethyl (2S,3R)-3-ethylhexahydroquinolinate (+)-(3S,17S)-14-oxo-E-homo-eburnane methyl (1α,12bα,E)-α-[(2,4-dinitrophenyl)hydrazono]-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine-1-propanoate (2S,3R)-1-(2-(1H-indol-3-yl)ethyl)-3-ethyl-3-(methoxycarbonyl)piperidine-2-carboxylic acid hydroxy-16 dehydro-1 vincadifformine (S)-3-ethyl-1-[2-(1H-indol-3-yl)ethyl]-3-(3-{[(1,1-dimethylethyl)diphenylsilyl]oxy}propyl)-2-piperidinone O-methyl vincamine dimethyl (2S,3R)-3-ethyl-1-[2-(3-indolyl)ethyl]hexahydroquinolate perchlorate d'apovincamine 3α-epivincamine (+/-)-1α-ethyl-1β-(2',2'-diethoxycarbonylethyl)-1,2,3,4,6,7,12,12bα-octahydro-indolo[2,3-a]quinolizine 14,15-dihydro-1,14-seco-21-nor-eburnamenin-20-ol (R)-3-ethyl-1-[2-(1H-indol-3-yl)ethyl]-2,4-dioxo-3-piperidinepropanoic acid methyl ester 3-ethyl-1-[2-(1H-indol-3-yl)ethyl]-2,4-piperidinedione dimethyl (2S,3R)-3-ethyl-1-(9-phenylfluoren-9-yl)hexahydroquinolinate 1-(2-(2-(2,4-dinitrophenyl)hydrazono)-3-methoxy-3-oxopropyl)-1-ethyl-2,3,4,6,7,12-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium bromide 甲醇 15a-homo-eburnamenine-14,15-dione 15-oxime

下游产品

(3alpha,14beta,16alpha)-14,15-二氢-14-羟基埃那美宁-14-甲醇 (-)-象牙(洪达木)酮宁 3α-epivincamine 长春西汀长春胺