百科

胆固醇

胆固醇

CAS号：57-88-5

英文名：cholesterol

分子式

C27H46O

熔点

148-150°C

密度

1.06

分子量

386.654

沸点

360 °C

溶解度

negligible

信号词

危险品标志

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化合物简介

Vat Yellow 1 is sort of vat dye. Molecular structure of Vat Yellow 1 is anthraquinone.

基本信息

中文名称

胆固醇

英文名称

cholesterol

中文别名

左旋倍他洛尔、胆固、3β-Hydroxy-5-cholestene、胆脂醇

英文别名

20-Dihydro-11-deoxycortisol、cholesterin、Cholest-5-en-3-ol (3β)-、20-Dihydro Cortexolone、Cholesterol

CAS号

57-88-5

分子式

C27H46O

分子量

386.654

精确质量

386.355

PSA

20.23

LOGP

7.3887

编号系统

MDL号

MFCD00003646

物化性质

外观与性状

白色结晶固体

密度

1.06

沸点

360 °C

熔点

148-150°C

闪点

250 °C

折射率

1.525

水溶解性

negligible

稳定性

Stable under normal shipping and handling conditions.

储存条件

2-8ºC

安全信息

RTECS号

FZ8400000

安全说明

S24/25-S22-S36/37

危险类别码

R10

WGK Germany

1

危险品运输编码

UN 1170 3/PG 3

海关编码

2906131000

危险品标志

Xn

生产方法及用途

生产方法

1.以牲畜脑组织为原料干脑粉的制备取新鲜动物脑及脊髓(除去脂肪和脊髓膜),绞碎,40-50℃烘干,得干脑粉。脑(猪、牛、羊)[40-50℃]→干脑粉粗胆固醇结晶的制备干脑粉加1.2倍量丙酮浸渍,不断搅拌,提取4.5h,反复提取6次,过滤,合并提取液,蒸馏回收丙酮,得黄色固体物。加 10倍量乙醇,加热回流1h,得胆固醇乙醇溶液,过滤,滤液在0-5℃冷却,静置,析出晶体,过滤,得粗胆固醇结晶。干脑粉[丙酮]→黄色固体[乙醇]→胆固醇乙醇溶液[0-5℃]→粗胆固醇结晶精制胆固醇的制备取粗胆固醇结晶加5倍量乙醇,加5%-6%硫酸,加热回流8h,得水解液,0-5℃冷却,析出晶体,过滤,得晶体,加乙醇洗至中性。将洗至中性的晶体加10倍量95%乙醇,加3%活性炭,加热回流脱色1h,保温过滤,滤液0-5℃冷却结晶,反复3次,过滤,收集结晶,压干,挥去乙醇,70-80℃真空干燥,得精制胆固醇。粗胆固醇结晶[乙醇,H2SO4]→ 水解液[0-5℃]→晶体[乙醇,活性炭]→ 精制胆固醇。
2. 烟草:FC,8, 32, 41, 43。

用途

是制造激素的重要原料，并可用作乳化剂。

合成路线

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(24E)-(28-(2)H)ergosta-5,24(28)-dien-3β-ol

(24E)-(28-(2)H)ergosta-5,24(28)-dien-3β-ol

植物甾醇

胆固醇

菜油甾醇

isofucosterol

海关数据

共找到1个国家海关数据 >

国家/地区名称	海关编码	更新时间	操作
中国	2906131000	2019-03	查看

上游原料

共找到136个上游原料 >

N,N-二甲基甲酰胺

N,N-二甲基甲酰胺

1-((2aR,3aR,5aR,5bS,7aS,7bS,8aR,9aS,9bR)-2-methoxy-5a,7a-dimethyltetradecahydrocyclopropa[1',7a']indeno[5',4':4,5]indeno[1,2-b]oxiren-7b(2H)-yl)ethan-1-one

1-((2aR,3aR,5aR,5bS,7aS,7bS,8aR,9aS,9bR)-2-methoxy-5a,7a-dimethyltetradecahydrocyclopropa[1',7a']indeno[5',4':4,5]indeno[1,2-b]oxiren-7b(2H)-yl)ethan-1-one

5-胆甾烯-3-酮

5-胆甾烯-3-酮

O-allylcholesterol

O-allylcholesterol

(17Z)-6β-methoxy-3α,5-cyclo-5α-pregn-17(20)-ene

(17Z)-6β-methoxy-3α,5-cyclo-5α-pregn-17(20)-ene

cholester-3β-yl thiobenzoate

cholester-3β-yl thiobenzoate

下游产品

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4-胆甾烯-3-酮

4-胆甾烯-3-酮

2,3-丁二酮

胆固醇醋酸酯

胆固醇醋酸酯

5-孕烯-3beta,20Beta-二醇

5-孕烯-3beta,20Beta-二醇

5-胆甾烯-3-酮

5-胆甾烯-3-酮

胆固醇棕榈酸酯

胆固醇棕榈酸酯

上游原料

N,N-二甲基甲酰胺 1-((2aR,3aR,5aR,5bS,7aS,7bS,8aR,9aS,9bR)-2-methoxy-5a,7a-dimethyltetradecahydrocyclopropa[1',7a']indeno[5',4':4,5]indeno[1,2-b]oxiren-7b(2H)-yl)ethan-1-one 5-胆甾烯-3-酮 O-allylcholesterol (17Z)-6β-methoxy-3α,5-cyclo-5α-pregn-17(20)-ene cholester-3β-yl thiobenzoate [10,13-二甲基-17-(6-甲基庚烷-2-基)-2,3,4,7,8,9,11,12,14,15,16,17-十二氢-1H-环戊并[a]菲-3-基] 4-甲基苯磺酸酯氯乙酸胆固醇 Cholest-5-en-3-ol, 20-fluoro-, (3β)- 3-O-叔-丁基二甲基硅烷基胆固醇 5α,6β-dibromocholestan-3β-ol cholest-5-en-3β-yl diazoacetate 1-((cholesteryloxy)methyl)-4-methoxybenzene 2-(((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-1,4-dioxane (5α)-cholestane-3β,5,6β-triol 双丙酮半乳糖二甲胺 2-((3S,10R,13R,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[α]phenanthren-3-yloxy)tetrahydro-2H-pyran 乙酸酐 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (perylen-3-ylmethyl) carbonate 4-methylpentyllithium 乙酸汞 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate 24ξ-flourocholesterol (3S,5R,8S,9S,10R,13R,14S,17R)-5,6-Dibromo-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol (3S)-10,13-二甲基-17-(6-甲基庚烷-2-基)-1,2,3,4,6,7,8,9,11,12,14,15,16,17-十四氢环戊烯并[a]菲-3,5-二醇胆固醇-5Alpha,6Alpha-环氧化物胆固醇醋酸酯 (2R)-2-((1aR,3aR,3bS,5aS,8aS,8bR,10aR)-10-methoxy-3a,5a-dimethyl-1,1a,2,3,3a,3b,4,5,5a,8,8a,8b,9,10-tetradecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-6-methylheptan-4-one (1aR,3aR,3bS,5aS,7R,8aS,8bR,10aR,E)-6-ethylidene-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-7-yl 5-methyl-3-oxohexanoate (17E)-6β-methoxy-3α,5-cyclo-5α-pregn-17(20)-en-16α-ol 胆固醇硫酸酯钠盐 (3A,5R,6B)-6-甲氧基-3,5-环胆甾烷 (24E)-(28-(2)H)ergosta-5,24(28)-dien-3β-ol 6β-phenylsulfanyl-3α,5α-cyclo-cholestane 16,17-alpha环氧孕烯醇酮 cholesteryl-2-tetrahydrofuran cholester-3β-yl benzyl ether 25-氟胆固醇 6β-Chlor-3,5-cyclocholestan monovinylacetylene-d4 cholesterol triethylsilyl ether 乙酸锂 3β-(1-Ethoxyethoxy)-5-cholestene 环己烷 Cholest-5-en-3-ol, 22-fluoro-, (3β,22S)- 甲醇 5-胆甾烯

下游产品

4-胆甾烯-3-酮 2,3-丁二酮胆固醇醋酸酯 5-孕烯-3beta,20Beta-二醇 5-胆甾烯-3-酮胆固醇棕榈酸酯 cholest-4-ene-3β,6β-diol diacetate α-(3β)-cholest-5-en-3-yl-2,3,4,6-tetra-O-acetyl-D-glucopyranoside 5α-cholestane-3β,6β-diol 6β-acetoxy-3β-hydroxycholest-4-ene cholesteryl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside 胆固醇硬脂酸酯 Olesoxime [(E)-[10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ylidene]amino]urea 胆甾烯基甲酸酯 cholesteryl α- and β-2,3,4,6-tetra-O-acetyl-D-glucosides β-(3Beta)-cholest-5-en-3-yl-2,3,4,6-tetra-O-acetyl-D-glucopyranoside 7-去氢胆固醇 (3b)-(3'b)-3,3'-氧基二-胆甾-5-烯 3,4,6-Tri-O-acetyl-1,2-cholesterylorthoacetyl-α-D-glucopyranose 5-胆甾烯 cholest-5-3-β-yl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 氯化胆固醇 ethyl 2-(4-thieno<2,3-b>pyridyl)-2-cyanoacetate 4,6-胆固醇二烯-3-酮 6-硝基胆固醇乙酸酯 2-pyridyl 1,1-diethylpropyl disulphide 反-肉桂酸胆固醇酯 ethyl 2-cyano-2-(quinolin-4(1H)-ylidene)acetate 20Alpha-羟基胆固醇胆甾-3,5-二烯胆甾醇溴