1,5,7-三氮杂双环[4.4.0]癸-5-烯

Triazabicyclodecene (1,5,7-Triazabicyclo[4.4.0]dec-5-ene or TBD) is a commercially available bicyclic strong guanidine base (pKa = 25.98 in CH3CN and pKa = 21.00 in THF). TBD is an organic soluble base which has been used effectively for a variety of base-mediated organic transformations. It is also known in deprotonated form (at the 7-position), often as a ligand, for instance in Ditungsten tetra(hpp)