亮氨酸脑啡肽

亮氨酸脑啡肽

CAS号：58822-25-6

英文名：[LEU5]-ENKEPHALIN

分子式

C28H37N5O7

熔点

密度

1.274 g/cm3

分子量

555.623

沸点

998.8ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine. Leu-enkephalin has agonistic actions at both the μ- and δ-opioid receptors, with significantly greater preference for the latter. It has little to no effect on the κ-opioid receptor.

基本信息

中文名称

亮氨酸脑啡肽

英文名称

[LEU5]-ENKEPHALIN

中文别名

N-[N-[N-(N-L-酪氨酰甘氨酰)甘氨酰]-L-苯丙氨酰]-L-亮氨酸

英文别名

ENKEPHALIN L、Leu-Enkelphalin、LEUCINE-ENKEPHALIN、L-TYR-GLY-GLY-PHE-LEU、L-leucine enkephalin、LEU-ENKEPHALIN、enkephalin,leucine、TYR-GLY-GLY-PHE-LEU、H-TyrGlyGlyPheLeu-OH、YGGFL、SGS 518 oxalate、H2N-Tyr-Gly-Gly-Phe-Leu-COOH

CAS号

58822-25-6

分子式

C28H37N5O7

分子量

555.623

精确质量

555.269

PSA

199.95

LOGP

2.1013

编号系统

UNII

RI01R707R6

物化性质

外观与性状

白色冻干的粉末

密度

1.274 g/cm3

沸点

998.8ºC at 760 mmHg

闪点

557.8ºC

折射率

1.586

储存条件

-20ºC

安全信息

安全说明

S22-S24/25

WGK Germany

3

合成路线

共找到4条合成路线 >

4-nitrobenzyl glycyl-L-phenylalanyl-L-leucinate hydrobromide

4-nitrobenzyl glycyl-L-phenylalanyl-L-leucinate hydrobromide

亮氨酸脑啡肽

亮氨酸脑啡肽

上游原料

共找到122个上游原料 >

Boc-Tyr (Bn)-Gly-Gly-Phe-Leu-OBn

Boc-Tyr (Bn)-Gly-Gly-Phe-Leu-OBn

BOC-L-苯丙氨酸

BOC-L-苯丙氨酸

(S)-4-Methyl-2-{(S)-2-[2-(2-methyl-propane-2-sulfonyl)-allyloxycarbonylamino]-3-phenyl-propionylamino}-pentanoic acid benzyl ester

(S)-4-Methyl-2-{(S)-2-[2-(2-methyl-propane-2-sulfonyl)-allyloxycarbonylamino]-3-phenyl-propionylamino}-pentanoic acid benzyl ester

Boc-Tyr(2,6-Cl2Bzl)-Gly-Gly-Phe-OMe

Boc-Tyr(2,6-Cl2Bzl)-Gly-Gly-Phe-OMe

(BOC)2Phe-F

BOC-LEU-ENKEPHALIN

BOC-LEU-ENKEPHALIN

下游产品

共找到7个下游商品 >

甘氨酰甘氨酰-L-苯丙氨酸

甘氨酰甘氨酰-L-苯丙氨酸

L-亮氨酸

对硝基苯酚

对硝基苯酚

DL-亮氨酸

L-酪氨酸

H-TYR-GLY-GLY-PHE-OH

H-TYR-GLY-GLY-PHE-OH

上游原料

Boc-Tyr (Bn)-Gly-Gly-Phe-Leu-OBn BOC-L-苯丙氨酸 (S)-4-Methyl-2-{(S)-2-[2-(2-methyl-propane-2-sulfonyl)-allyloxycarbonylamino]-3-phenyl-propionylamino}-pentanoic acid benzyl ester Boc-Tyr(2,6-Cl2Bzl)-Gly-Gly-Phe-OMe (BOC)2Phe-F BOC-LEU-ENKEPHALIN L-phenylalanyl-L-leucine tert-butyl ester Boc2-Gly-Phe-Leu-OBzl Gly-Phe-Leu(t-Bu) N-[N-[glycyl]glycyl]-L-3-phenylalanine methyl ester hydrochloride Boc2-Phe-Leu-OBzl 9H-芴-9-基甲基{(2S)-3-[4-(苄氧基)苯基]-1-氯-1-氧代-2-丙基}氨基甲酸酯 Dts-Tyr(t-Bu)-Gly-Gly-Phe-Leu-OH benzyl ester of N-benzyloxycarbonyl-O-benzyltyrosylglycylglycylphenylalanylleucine DC-FM-bar-Gly-Phe-Leu-O-t-Bu L-苯基丙氨酸叔丁酯 DC-FM-bar-Tyr(t-Bu)-Gly-Gly-Phe-Leu-O-t-Bu 2-(tert-butylsulfonyl)-2-propenyloxycarbonylphenylalanyl chloride 4-nitrobenzyl glycyl-L-phenylalanyl-L-leucinate hydrobromide Trt-Tyr-Gly-Gly-Phe-Leu-ODpm Boc-Gly-Gly-Phe-OMe Z(OMe)-Phe-Leu-OBzl Gly-Gly-Phe-Leu-OBn 4-nitrobenzyl ester of N-t-butyloxycarbonylglycylglycyl-L-phenylalanyl-L-leucine (BOC)2Tyr(Bn)-F Z(OMe)-Gly-Gly-Phe-Leu-OBzl (BOC)2Tyr(Bn)-OH Boc-Tyr(2,6-Cl2Bzl)-Gly-Gly-Phe-OH (2S)-2-[(4-methoxyphenyl)methoxycarbonylamino]-3-phenylpropanoic acid leucine-enkephalin methyl ester L-亮氨酸苄基酯 (BOC)2Phe-OH Boc-Tyr-Gly-Gly-Phe-Leu-OBut hydrochloride of 4-nitrobenzyl ester of glycyl-glycyl-L-phenylalanyl-L-leucine tert-butyl 2-(tert-butylsulfonyl)-2-(propenyloxycarbonyl)-L-phenylalaninate DC-FM-bar-Phe-Leu-O-t-Bu DC-FM-bar-Phe-OH Fmoc-Tyr(Bzl)-Gly-Gly-Phe-Leu-OBzl Boc2-Gly-Gly-Phe-Leu-OBzl L-苯丙氨酸 Boc-Phe-Leu-OBn Dts-Tyr-Gly-Gly-Phe-Leu-OH 2-(t-Butylsulfonyl)-2-propenyloxycarbonyl-L-phenylalanine DC-FM-bar-Gly-Gly-Phe-Leu-O-t-Bu L-phenylalanyl-L-leucine benzyl ester Boc-Tyr(CLz)-Gly-Gly-Phe-Leu-OH Z(OMe)-Gly-Phe-Leu-OBzl Boc-Tyr(2,6-Cl2Bzl)-Gly-Gly-Phe-Leu-OMe Z(OMe)-Phe-OTAP

下游产品

甘氨酰甘氨酰-L-苯丙氨酸 L-亮氨酸对硝基苯酚 DL-亮氨酸 L-酪氨酸 H-TYR-GLY-GLY-PHE-OH 亮氨酰-脑啡肽硫酸酯