化合物简介
Chloropyramine is a classical (\"old\" or first generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.
基本信息
中文名称
氯吡拉敏
英文名称
N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
中文别名
氯吡胺、2-[(4-氯苄基)[2-(二甲基氨基)乙基]氨基]吡啶
英文别名
Chlorpyramine、Chloropyramine、Halopyramine、N-(4-Chlor-benzyl)-N\',N\'-dimethyl-N-[2]pyridyl-aethylendiamin、Anaphylline、Avapena、Chlorpyraminum、Synpen、Suprastin、N-[(4-chlorophenyl)methyl]-N\',N\'-dimethyl-N-2-pyridinyl-1,2-ethanediamine、N-[(4-chlorophenyl)methyl]-N-[2-(dimethylamino)ethyl]pyridin-2-amine、N-(4-chloro-benzyl)-N\',N\'-dimethyl-N-[2]pyridyl-ethylenediamine、Chlorneoantergan、Synopen、N-(4-Chlor-benzyl)-N\',N\'-dimethyl-N-<2>pyridyl-ethylendiamin
CAS号
59-32-5
分子式
C16H20ClN3
分子量
289.803
精确质量
289.135
PSA
19.37
LOGP
3.3032
编号系统
UNII
2K3L8O9SOV
物化性质
密度
1.158g/cm3
沸点
413.5ºC at 760 mmHg
闪点
203.9ºC
折射率
1.6
合成路线
上游原料
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