化合物简介
Zoxazolamine (INN, USAN, BAN) (brand name Contrazole, Deflexol, Flexin, Miazol, Uri-Boi, Zoxamine, Zoxine) is a muscle relaxant that is no longer marketed. It was synthesized in 1953 and introduced clinically in 1955 but was withdrawn due to hepatotoxicity. One of its active metabolites, chlorzoxazone, was found to show less toxicity, and was subsequently marketed in place of zoxazolamine. These drugs activate IKCa channels.
基本信息
中文名称
2-氨基-5-氯苯并噁唑
英文名称
2-Amino-5-chlorobenzoxazole
中文别名
苯并恶唑胺、氯苯唑胺
英文别名
2-Benzoxazolamine, 5-chloro-、5-chloro-1,3-benzoxazol-2-amine
CAS号
61-80-3
分子式
C7H5ClN2O
分子量
168.58
精确质量
168.009
PSA
52.05
LOGP
2.6446
编号系统
MDL号
MFCD00005770
物化性质
密度
1.481 g/cm3
沸点
316.8ºC at 760 mmHg
熔点
181-184°C(lit.)
闪点
145.4ºC
折射率
1.692
储存条件
库房通风低温干燥
安全信息
RTECS号
DM4550000
安全说明
S26-S36
WGK Germany
3
危险类别码
R20/21/22; R36/37/38
海关编码
2934999090
危险品标志
Xn
危险性描述
H302; H312; H315; H319; H332; H335
信号词
Warning
危险性防范说明
P261; P280; P305 + P351 + P338
危险标志
GHS07
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