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Inhoffen Lythgoe diol

Inhoffen Lythgoe diol

CAS号：64190-52-9

英文名：Inhoffen-Lythgoe diol

分子式

C13H24O2

熔点

108-110 °C

密度

分子量

212.328

沸点

溶解度

信号词

危险品标志

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化合物简介

A key intermediate for the preparation of Vitamin D metabolites and analogs.

基本信息

中文名称

Inhoffen Lythgoe diol

英文名称

Inhoffen-Lythgoe diol

中文别名

英文别名

Lythgoe-inhoffendiol、1-(2-HYDROXY-1-METHYL-ETHYL)-7A-METHYL-OCTAHYDRO-INDEN-4-OL、LYTHGOE DIOL、Inhoffen Lythgoe diol、(S)-C(OH)D(OH)、(4S,7AR)-1-[(2S)-1-HYDROXYPROPAN-2-YL]-7A-METHYL-OCTAHYDRO-1H-INDEN-4-OL、Lythgoe-inhoffen diol、1H-INDENE-1-ETHANOL,OCTAHYDRO-4-HYDROXY-B,7A-DIMETHYL-, (BS,1R,3AR,4S,7AR)-、(1R,3AR,4S,7AR)-1-[(1S)-2-HYDROXY-1-METHYL-ETHYL]-7A-METHYL-1,2,3,3A,4,5,6,7-OCTAHYDROINDEN-4-OL

CAS号

64190-52-9

分子式

C13H24O2

分子量

212.328

精确质量

212.178

PSA

40.46

LOGP

2.1921

编号系统

MDL号

MFCD00144484

物化性质

熔点

108-110 °C

安全信息

海关编码

2906199090

合成路线

共找到14条合成路线 >

维生素D2

Inhoffen Lythgoe diol

Inhoffen Lythgoe diol

上游原料

共找到28个上游原料 >

(1S-cis)-(1,1-dimethylethoxy)-2,3,5,6,7,7a-hexahydro-7a-methyl-5-oxo-1H-indene-4-carboxylic acid

(1S-cis)-(1,1-dimethylethoxy)-2,3,5,6,7,7a-hexahydro-7a-methyl-5-oxo-1H-indene-4-carboxylic acid

(3beta,5Z,7R,8alpha,22E)-9,10-开环麦角甾-5,10(19),22-三烯-3,7,8-三醇

(3beta,5Z,7R,8alpha,22E)-9,10-开环麦角甾-5,10(19),22-三烯-3,7,8-三醇

(3aR,4S,7aS)-7a-Methyl-1-vinylidene-octahydro-inden-4-ol

(3aR,4S,7aS)-7a-Methyl-1-vinylidene-octahydro-inden-4-ol

methyl 5-methyl-11-triethylsilylundec-5-en-9-ynoate

methyl 5-methyl-11-triethylsilylundec-5-en-9-ynoate

<3aR-(3aα,4β,7aβ)>-7a-methyl-4-acetyloxy-octahydro-1H-inden-1-one

<3aR-(3aα,4β,7aβ)>-7a-methyl-4-acetyloxy-octahydro-1H-inden-1-one

(E)-(9-bromo-7-methylnon-6-en-2-yn-1-yl)triethylsilane

(E)-(9-bromo-7-methylnon-6-en-2-yn-1-yl)triethylsilane

下游产品

共找到12个下游商品 >

骨化三醇

(1R,1’S)-八氢-1-(2’-碘-1’-甲基乙基)-7a-甲基-茚-4-酮

(1R,1’S)-八氢-1-(2’-碘-1’-甲基乙基)-7a-甲基-茚-4-酮

(2S)-2-[(4S,7aR)-4-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-7A-甲基八氢-1H-茚-1-基]丙基4-甲基苯磺酸酯

(2S)-2-[(4S,7aR)-4-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-7A-甲基八氢-1H-茚-1-基]丙基4-甲基苯磺酸酯

1α-((tert-butyldimethylsilyl)-oxy)-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D3 tert-butyldimethylsilyl ether

1α-((tert-butyldimethylsilyl)-oxy)-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D3 tert-butyldimethylsilyl ether

(1R,4S,7aR)-1-[(2S)-1-羟基-2-丙基]-7a-甲基八氢-1H-茚-4-基苯甲酸酯

(1R,4S,7aR)-1-[(2S)-1-羟基-2-丙基]-7a-甲基八氢-1H-茚-4-基苯甲酸酯

2,3,3a,6,7,7a-六氢-5’,7a-二甲基-4-羟基-茚-(1R)-1’-戊酸甲酯4-O-三氟甲烷磺酸酯

2,3,3a,6,7,7a-六氢-5’,7a-二甲基-4-羟基-茚-(1R)-1’-戊酸甲酯4-O-三氟甲烷磺酸酯

上游原料

(1S-cis)-(1,1-dimethylethoxy)-2,3,5,6,7,7a-hexahydro-7a-methyl-5-oxo-1H-indene-4-carboxylic acid (3beta,5Z,7R,8alpha,22E)-9,10-开环麦角甾-5,10(19),22-三烯-3,7,8-三醇 (3aR,4S,7aS)-7a-Methyl-1-vinylidene-octahydro-inden-4-ol methyl 5-methyl-11-triethylsilylundec-5-en-9-ynoate <3aR-(3aα,4β,7aβ)>-7a-methyl-4-acetyloxy-octahydro-1H-inden-1-one (E)-(9-bromo-7-methylnon-6-en-2-yn-1-yl)triethylsilane (2S,4S)-4-(((3aR,4S,7aS)-7a-methyl-1-vinylideneoctahydro-1H-inden-4-yl)oxy)pentan-2-ol (1S-(1β,3aα,4β,7aβ))-1-((1,1-dimethylethyl)oxy)-7a-methyl-octahydro-1H-inden-4-ol acetate ((E)-10-((4S,6S)-4,6-dimethyl-1,3-dioxan-2-yl)-7-methyldec-6-en-2-yn-1-yl)triethylsilane 维生素D2 (1S-(1β,3aα,4β,7aβ))-1-(octahydro-7a-methyl-1-((1,1-dimethylethyl)-oxy)-1H-inden-4-yl)ethanone De-A,B-8-Oxo-23,24-dinorcholan-22-ol 2-(4-羟基-7a-甲基八氢-1H-茚-1-基)丙基4-甲基苯磺酸酯 (1R,4S,7aR)-1-[(2R,3E,5R)-5,6-二甲基-3-庚烯-2-基]-7A-甲基八氢-1H-茚-4-醇 (3aR,4S,7aS)-(Z)-1-ethylidene-7a-methyloctahydro-1H-4-indenol [1R-(3aβ(S*),7β,7aα)]-β,3a-dimethyl-4-hydroxy-(3a,4,5,6,7,7a)hexahydro-1H-indene-1-ethanol 5-methyl-11-triethylsilylundec-5-en-9-ynal (1'S,3aR,4S,7aS)-1'-(1'-methyl-2'-hydroxyethyl)-1-octahydro-7a-methyl-22-hydroxy-1H-inden-4-ol acetate (24R,22E)-de-A,B-8β-<(tert-butyldimethylsilyl)oxy>ergost-22-ene (3aR-(1Z,3aα,4β,7aβ))-1-ethylideneoctahydro-7a-methyl-1H-inden-4-ol acetate (3aR,4S,7aS)-7a-methyl-1-vinylideneoctahydro-1H-inden-4-yl acetate (3S,5Z,7E,14Xi,22E)-3-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-9,10-开环麦角甾-5,7,10,22-四烯 (S)-2-((1R,3aR,4S,7aR)-4-(tert-butyldimethylsilyloxy)-7a-methyloctahydro-1H-inden-1-yl)propan-1-ol [1S-(1β,3aα,4β,7aβ)]-7a-methyl-octahydro-1H-indene-1,4-diol 4-acetate 3β-O-(triisopropylsilyl)-7,8-dihydroxy-7,8-dihydrovitamin D2

下游产品

骨化三醇 (1R,1’S)-八氢-1-(2’-碘-1’-甲基乙基)-7a-甲基-茚-4-酮 (2S)-2-[(4S,7aR)-4-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-7A-甲基八氢-1H-茚-1-基]丙基4-甲基苯磺酸酯 1α-((tert-butyldimethylsilyl)-oxy)-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D3 tert-butyldimethylsilyl ether (1R,4S,7aR)-1-[(2S)-1-羟基-2-丙基]-7a-甲基八氢-1H-茚-4-基苯甲酸酯 2,3,3a,6,7,7a-六氢-5’,7a-二甲基-4-羟基-茚-(1R)-1’-戊酸甲酯4-O-三氟甲烷磺酸酯 2-(4-羟基-7a-甲基八氢-1H-茚-1-基)丙基4-甲基苯磺酸酯 26,27-二去甲基-1,3-(叔-丁基二甲基硅烷基)(5Z)-骨化三醇24-羧酸甲酯 (1R,3aR,4S,7aR)-八氢-1-[(1S)-2-碘-1-甲基乙基]-7a-甲基-1H-茚-4-醇 2,3,3a,6,7,7a-六氢-2S,7a-二甲基-4-羟基-茚-1R-(1’-碘)乙烷4-O-三氟甲基磺酸酯 (S)-2-[(1R,3aR,4S,7aR)-octahydro-4-[(1,1-dimethylethyl)dimethylsilyloxy]-7a-methyl-1H-inden-1-yl]propanal [1R-[1β(R*),3aα,4β,7aβ]]-octahydro-4-hydroxy-β,7a-dimethyl-1H-indene-1-propanenitrile