化合物简介
2-Benzamido-1,4-naphthoquinone belongs to a novel class of small molecule inhibitors of histone deacetylase (HDAC6), a family of enzymes that play significant role in numerous biological processes and diseases. 2-Benzamido-1,4-naphthoquinone was also shown to be an activation blocker of nuclear factor-kB (NF-kB).
基本信息
中文名称
2-苯甲酰氨基-1,4-萘醌
英文名称
N-(1,4-dioxonaphthalen-2-yl)benzamide
中文别名
英文别名
2-benzoylamino-1,4-naphthoquinone、ppm-18、2-Benzamino-1,4-naphthochinon
CAS号
65240-86-0
分子式
C17H11NO3
分子量
277.274
精确质量
277.074
PSA
63.24
LOGP
2.7704
编号系统
MDL号
MFCD18427708
物化性质
密度
1.35g/cm3
沸点
517.5ºC at 760 mmHg
闪点
208.2ºC
折射率
1.666