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4'-去甲氧基表鬼臼毒素

4'-去甲氧基表鬼臼毒素

CAS号：6559-91-7

英文名：4'-demethylepipodophyllotoxin

分子式

C21H20O8

熔点

246-248ºC

密度

1.446 g/cm3

分子量

400.379

沸点

626.5ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

A potent inhibitor of microtubule assembly.

基本信息

中文名称

4'-去甲氧基表鬼臼毒素

英文名称

4'-demethylepipodophyllotoxin

中文别名

4’-去甲表鬼臼毒素

英文别名

4-DEMETHYL EIPODOPHYLLOTOXIN、4\'-demethyl-9-epipodophyllotoxin、4-Domethylpodophyllotoxin,4\'-demethyl-epi-Podophyllotoxin、4\'-demethyl-epipodophyllotoxin、4\'-demethyl-4-epipodophyllotoxin、4\'-DEMETHYLEPIPODOPHYLLOTOXINE、4\'-Demethylepipodophyllotoxin、4\'-O-demethylepipodophyllotoxin、4\'-DMEP

CAS号

6559-91-7

分子式

C21H20O8

分子量

400.379

精确质量

400.116

PSA

103.68

LOGP

2.1062

编号系统

EINECS号

613-823-0

物化性质

外观与性状

白色结晶粉末

密度

1.446 g/cm3

沸点

626.5ºC at 760 mmHg

熔点

246-248ºC

闪点

224.4ºC

折射率

1.616

储存条件

-20ºC Freezer

合成路线

共找到11条合成路线 >

鬼臼毒素

4'-去甲氧基表鬼臼毒素

4'-去甲氧基表鬼臼毒素

上游原料

共找到8个上游原料 >

4-bromo-4'-demethyl-epipodophyllotoxin

4-bromo-4'-demethyl-epipodophyllotoxin

4,4'-bis(tert-butyldimethylsilyl)-4'-O-demethylepipodophyllol

4,4'-bis(tert-butyldimethylsilyl)-4'-O-demethylepipodophyllol

(5R,5aR,8aR,9S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-iodo-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one

(5R,5aR,8aR,9S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-iodo-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one

7-chlorodeoxypodophyllotoxin

7-chlorodeoxypodophyllotoxin

4'-O-demethyl-4β-bromo-4-desoxypodophyllotoxin

4'-O-demethyl-4β-bromo-4-desoxypodophyllotoxin

4β-bromo-4-desoxypodophyllotoxin

4β-bromo-4-desoxypodophyllotoxin

下游产品

共找到11个下游商品 >

4 ’-去甲去氧鬼臼毒素

4 ’-去甲去氧鬼臼毒素

ethyl 4-[[(3aS,4S,9R,9aR)-9-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-1-oxo-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-4-yl]amino]benzoate

ethyl 4-[[(3aS,4S,9R,9aR)-9-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-1-oxo-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-4-yl]amino]benzoate

(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(4-hydroxyphenyl)sulfanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(4-hydroxyphenyl)sulfanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

(3aS,4S,9R,9aR)-4-[(4-氟苯基)氨基]-9-(4-羟基-3,5-二甲氧基苯基)-6,7-二甲氧基-3a,4,9,9a-四氢-3H-萘并[3,2-c]呋喃-1-酮

(3aS,4S,9R,9aR)-4-[(4-氟苯基)氨基]-9-(4-羟基-3,5-二甲氧基苯基)-6,7-二甲氧基-3a,4,9,9a-四氢-3H-萘并[3,2-c]呋喃-1-酮

依托泊甙

4’-去甲基表鬼臼毒素-Β-D-葡萄糖甙

4’-去甲基表鬼臼毒素-Β-D-葡萄糖甙

上游原料

4-bromo-4'-demethyl-epipodophyllotoxin 4,4'-bis(tert-butyldimethylsilyl)-4'-O-demethylepipodophyllol (5R,5aR,8aR,9S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-iodo-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one 7-chlorodeoxypodophyllotoxin 4'-O-demethyl-4β-bromo-4-desoxypodophyllotoxin 4β-bromo-4-desoxypodophyllotoxin 醋酸鬼臼毒素

下游产品

4 ’-去甲去氧鬼臼毒素 ethyl 4-[[(3aS,4S,9R,9aR)-9-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-1-oxo-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-4-yl]amino]benzoate (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(4-hydroxyphenyl)sulfanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one (3aS,4S,9R,9aR)-4-[(4-氟苯基)氨基]-9-(4-羟基-3,5-二甲氧基苯基)-6,7-二甲氧基-3a,4,9,9a-四氢-3H-萘并[3,2-c]呋喃-1-酮依托泊甙 4’-去甲基表鬼臼毒素-Β-D-葡萄糖甙 (5S,5aS,8aR,9R)-5-[(4-氟苯基)氨基]-9-(4-羟基-3,5-二甲氧基-苯基)-5a,6,8a,9-四氢-5H-异苯并呋喃并[5,6-f][1,3]苯并二氧戊环-8-酮 (3aS,4S,9R,9aR)-9-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-4-(4-nitroanilino)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one (3aR,4S,9R,9aR)-4,6,7-trihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one (3aS,4S,9R,9aR)-4-(4-fluoroanilino)-6,7-dimethoxy-9-(3,4,5-trimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one ethyl 4-[[(5R,9S)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]benzoate