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7-乙基喜树碱

7-乙基喜树碱

CAS号：78287-27-1

英文名：7-Ethylcamptothecin

分子式

C22H20N2O4

熔点

236-241ºC

密度

1.43 g/cm3

分子量

376.405

沸点

752.9ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors.

基本信息

中文名称

7-乙基喜树碱

英文名称

7-Ethylcamptothecin

中文别名

7 - 乙基喜树碱

英文别名

(4s)-4,11-diethyl-4-hydroxy-1h-pyrano[3\',4\':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione、(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3\',4\':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione、7-ethyl-20(S)-camptothecin、SN 22、20(S)-7-ethylcamptothecin

CAS号

78287-27-1

分子式

C22H20N2O4

分子量

376.405

精确质量

376.142

PSA

81.42

LOGP

2.642

物化性质

外观与性状

淡粉红色固体

密度

1.43 g/cm3

沸点

752.9ºC at 760 mmHg

熔点

236-241ºC

闪点

409.1ºC

折射率

1.712

储存条件

-20ºC Freezer

安全信息

海关编码

2942000000

合成路线

共找到2条合成路线 >

7-ethyl-18,19-dehydrocamptothecin

7-ethyl-18,19-dehydrocamptothecin

7-乙基喜树碱

7-乙基喜树碱

上游原料

共找到12个上游原料 >

特戊基过氧化氢

特戊基过氧化氢

喜树碱

(S)-(7-(1-((2-(dimethylamino)ethyl)amino)-2-hydroxy-1-oxobutan-2-yl)-12-ethyl-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-8-yl)methyl benzoate

(S)-(7-(1-((2-(dimethylamino)ethyl)amino)-2-hydroxy-1-oxobutan-2-yl)-12-ethyl-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-8-yl)methyl benzoate

Acetic acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester

Acetic acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester

下游产品

共找到2个下游商品 >

7-乙基-10-羟基喜树碱

7-乙基-10-羟基喜树碱

伊立替康

上游原料

特戊基过氧化氢乙醛喜树碱 (S)-(7-(1-((2-(dimethylamino)ethyl)amino)-2-hydroxy-1-oxobutan-2-yl)-12-ethyl-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-8-yl)methyl benzoate 丙醛 Acetic acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester 二乙基酮丙醇 (S)-(7-(1-((2-(dimethylamino)ethyl)amino)-2-hydroxy-1-oxobutan-2-yl)-12-ethyl-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-8-yl)methyl 4-methoxybenzoate Isobutyric acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester 7-ethyl-18,19-dehydrocamptothecin

下游产品

7-乙基-10-羟基喜树碱伊立替康